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New Strategy May Be Valid Alternative To Traditional Antibiotics
Certainly there is strength in numbers, but only if those numbers can effectively communicate with one another. Now, a new study finds that administration of a novel small molecule which effectively disrupts a key bacterial communication process protects an animal host from infection. The research, published by Cell Press in the July 31st issue of the journal Molecular Cell, may lead to more effective treatments for bacterial infection that won"t encourage growth of treatment resistant bacteria.
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Radiant Research, Inc. Prepares For Upcoming H1N1 Vaccine Trials
Radiant Research, Inc. announced that it is actively recruiting subjects and establishing operational plans for upcoming H1N1 vaccine trials. The World Health Organization declared the H1N1 influenza outbreak a pandemic, and the CDC has shipped virus samples to several manufacturers with the hope of having vaccine available to the general public by the fall. Manufacturers will need to complete clinical trials prior to release of vaccine to the public.
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Discovery Of Neural Stem Cell Differentiation Factor
Neural stem cells represent the cellular backup of our brain. These cells are capable of self-renewal to form new stem cells or differentiate into neurons, astrocytes or oligodendrocytes. Astrocytes have supportive functions in the environment of neurons, while oligodendrocytes form the myelin layer around axons in order to accelerate neuronal signal transmission. But how does a neural stem cell "know" which way it is supposed to develop? On the molecular level receptors of the Notch family play a significant role in this process. So far, only stimulating extracellular ligands of Notch receptors had been described. Biochemists of Goethe University Medical School now describe a long time assumed but not yet identified soluble Notch inhibitor.
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ASH And EHA Jointly Announce Translational Research Training In Hematology Program

In an effort to foster global biomedical research that will ultimately lead to new and improved treatments for patients with blood diseases, the American Society of Hematology (ASH) and the European Hematology Association (EHA) have collaborated to create the Translational Research Training in Hematology (TRTH) program. This program will provide promising translational investigators an opportunity to undertake intensive training in the causes, diagnosis, and experimental treatment of hematologic disorders from some of the most recognized names in the field. "The next generation of translational researchers will need to understand how to direct research in both the European and U.S. systems," said TRTH co-director and past ASH president Kenneth Kaushansky, MD. "This unique cross-cultural program provides participants with ongoing mentoring, a supportive peer network, and a depth of knowledge and experience that will help position them as global leaders in the field of translational research." The inaugural TRTH will bring 20 early-career scientists to Marbella, Spain, during the week of March 20-26, 2010. Practical sessions will focus on career development, featuring career retrospectives from leaders in the field of hematology and panel discussions on grant preparation and funding s; while instructional sessions will prepare participants to conduct hypothesis-driven research, design phase I and II clinical trials, and utilize animal models, diagnostics, and biomarkers in translational research. "This rigorous one-week training course will allow participants to work with faculty in small groups to review and refine their individual research proposals," said program co-director and EHA president Willem Fibbe, MD. "The goal is for each of them to leave here with a competitive proposal so that they are ready to take the next step in applying for funding. We look forward to hearing about their progress when the group reconvenes at the ASH and EHA annual meetings." Medical trainees, biomedical trainees, and pharmaceutical doctorate trainees generally within 12 years of MD graduation or with less than eight years of post-doctoral experience are encouraged to apply; trainees must be an EHA or ASH member. Applications will be available on the ASH and EHA Web sites starting June 15, 2009. The American Society of Hematology is the world"s largest professional society concerned with the causes and treatment of blood disorders. Its mission is to further the understanding, diagnosis, treatment, and prevention of disorders affecting blood, bone marrow, and the immunologic, hemostatic, and vascular systems, by promoting research, clinical care, education, training, and advocacy in hematology. In September, ASH launched Blood: The Vital Connection , a credible online re addressing bleeding and clotting disorders, anemia, and cancer. It provides hematologist-approved information about these common blood conditions including risk factors, preventive measures, and treatment options. The European Hematology Association aims to promote excellence in clinical practice, research, and education in European hematology. Today, EHA - with over 3,000 active members from 95 countries - is a consolidated organization that pursues a large and growing number of projects and programs. European Hematology Association


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