Popular Articles

Indiana University School Of Medicine Researchers Develop Promising New Cancer Diagnostic Marker
Indiana University School of Medicine researchers have developed a new breast cancer diagnostic marker that could enable physicians to more easily determine which patients have a less aggressive form of the disease that may not require chemotherapy treatment.

Researchers Looking At Climate Change, Culture To Predict Land Abandonment In Russia
Kirsten de Beurs, an assistant geography professor in Virginia Tech"s College of Natural Res, has received a NASA grant to direct a large international land abandonment study in Russia with Grigory Ioffe of Radford University, Geoffrey Henebry of South Dakota State University, and in-country collaborator Tatyana Nefedova.
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Georgia Receives More Than $60M In Ryan White Funding
Georgia has received $63.9 million in Ryan White Program grants to fund treatment and other services for people living with HIV, the Atlanta Journal-Constitution reports. Grant recipients include county health departments and community organizations. The funding will be used to provide outpatient health services, health insurance coverage and support services, such as transportation and housing. According to the Journal-Constitution, more than $1.79 billion in Ryan White funding was allocated nationwide. Several HIV/AIDS organizations said that the funding is necessary to continue providing services for people living with the disease. Tracy Elliot, executive director of AID Atlanta, said that the funding is "critical," noting that more than 18,000 HIV/AIDS cases have been reported in Georgia. He continued, "We would have a lot of deaths without [the funding]. There would be significantly more illnesses without it and significantly more transmission of the disease without it." According to Elliot, "[m]edical treatment and medications are of no value if people cannot have access to them" (Poole, Atlanta Journal-Constitution, 5/19).
Cardiovascular

Alzheimer's Comment On Research That Genes In Early Onset Are Associated With Memory, Published In Nature, 28 July 2009

Memory is a fundamental function of nerve cells in the brain, and loss of memory is a key symptom in many people with Alzheimer"s disease. In order for memory to function correctly, nerve cells must be able to communicate effectively with each other. Many important proteins in the brain ensure that this communication is maintained between healthy nerve cells by monitoring the junctions, or synapses, between cells. This is also the location of production of amyloid-beta, which accumulates as plaques in Alzheimer"s disease. The gene PSEN1 is responsible for the protein presenilin1. Faulty versions of this gene are known to be linked to early onset Alzheimer"s disease. This new study shows that presenilin1 plays an important role in the functioning of synapses between nerve cells and suggests that the faulty protein disrupts communication between cells, thus affecting memory. The work also suggests that presenilin1 is linked with amyloid-beta and production of toxic plaques in the brain during Alzheimer"s disease. Alzheimer"s Society comment: "This study shows that a gene linked with early onset Alzheimer"s plays an important role in storing memory. This is an interesting finding which could lead to new research into how we can develop drug treatments that target this area. One million people will develop dementia in the next 10 years. We must act now. We need a national plan for dementia research and a tripling of investment to see research translated into better treatments for millions of people. Dementia is not a natural part of ageing; it is caused by diseases of the brain. 15,000 people under 65 live with dementia in the UK." Professor Clive Ballard Director of Research Alzheimer"s Society Reference Presenilins are essential for regulating neurotransmitter release. Chen Zhang1,2, Bei Wu1, Vassilios Beglopoulos1, Mary Wines-Samuelson1, Dawei Zhang1, Ioannis Dragatsis3, Thomas C. Su֬dhof2 & Jie Shen. Vol 460|30 July 2009| doi:10.1038/nature08177 Alzheimer"s Society


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