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U.S. Food And Drug Administration Approves ONGLYZA™ (saxagliptin) For The Treatment Of Type 2 Diabetes Mellitus In Adults
Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) announced that the U.S. Food and Drug Administration (FDA) approved ONGLYZA™ (saxagliptin), a dipeptidyl peptidase-4 (DPP4) inhibitor. ONGLYZA is indicated as an adjunct to diet and exercise to improve blood sugar (glycemic) control in adults for the treatment of type 2 diabetes mellitus. ONGLYZA once daily can be used in combination with commonly prescribed oral anti-diabetic medications metformin, sulfonylureas or thiazolidinediones (TZD) or as a monotherapy to significantly reduce glycosylated hemoglobin (A1C) levels. ONGLYZA should not be used for the treatment of type 1 diabetes or for the treatment of diabetic ketoacidosis (high levels of certain acids, known as ketones, in the blood or urine). ONGLYZA has not been studied in combination with insulin.

Salon Opinion Piece Questions Obama's Pick To Head Office Of Faith-Based And Community Partnerships
President Obama"s appointment of Alexia Kelley, founder of Catholics in Alliance for the Common Good, as director of the Office of Faith-Based and Community Partnerships at HHS "took the pro-choice movement by surprise," Salon contributor Frances Kissling, a former president of Catholics for Choice, writes in an opinion piece. According to Kissling, abortion-rights supporters "want to know ... why the post, which includes oversight of the department"s faith-based grant-making in family planning, HIV and AIDS and in small-scale research into the effect of religion and spirituality on early sexual behavior, has gone to someone who both believes abortion should be illegal and opposes contraception." She adds that Kelley and CACG have "sought to narrow the interpretation of common ground on abortion to efforts to reduce the number of abortions by providing women who are already pregnant with economic support for continuing the pregnancy and making adoption easier."Kissling notes that the "HHS budget for family-planning services grants to faith-based and community groups is more than $20 million." She asks, "Can pro-family-planning religious groups expect a fair deal from a director who believes that birth control, even for married couples, is immoral? Will programs that provide contraception to adolescents get funded?" Kissling continues that Obama"s February executive order on the office directed it to work to prevent teen pregnancy and reduce the need for abortion. She says of Kelley, "How can an opponent of the single most effective way to do both -- contraception -- lead that effort in HHS enthusiastically and effectively?"Kissling also notes Kelley"s accomplishments, writing that she "has much to offer in government -- but not at HHS." There are "10 other government agencies that have faith-based offices," and a "far less controversial placement could have been found at Labor, Housing and Urban Development, or the Department of Education," according to Kissling.Kissling continues that some leaders in the abortion-rights movement "have not yet commented on the Kelley appointment; most are still reeling from Dr. Tiller"s murder." However, "One hopes they will turn their attention to this appointment and demand a review of Kelley"s qualifications for this post," Kissling writes. She continues, "Pro-choice groups also contributed to the president"s election. They deserve appointees who agree with the platform on which the president ran. The pro-choice movement"s recommendations for pro-choice appointees to the faith-based office"s advisory council were ignored."Kissling adds that the "mission going forward must be to ensure that any additional staff members appointed to faith-based centers in Cabinet-level agencies reflect the pro-choice, pro-family-planning values of the administration." She concludes that as abortion-rights supporters "try to get to the bottom of the Kelley appointment, greater oversight of, and consultation on, future appointments need to be secured" (Kissling, Salon, 6/7).
News of the day
DxS And Exiqon Diagnostics To Host A Joint Personalized Cancer Therapy Workshop During The ASCO Annual Meeting
DxS Ltd, a personalized medicine company and leader in the field of companion diagnostics is working in partnership with Exiqon Diagnostics, a company on the forefront of individualizing cancer care through its novel molecular and cell-based oncology clinical laboratory services, to present a timely and relevant workshop on personalized cancer therapy.
Endocrinology

CBO: Health Reform Bills Bend Cost Curve In Wrong Direction

"Congress"s chief budget analyst delivered a devastating assessment yesterday of the health-care proposals drafted by congressional Democrats, fueling an insurrection among fiscal conservatives in the House and pushing negotiators in the Senate to redouble efforts to draw up a new plan that more effectively restrains federal spending," the Washington Post reports. President Obama and congressional Democrats have said bending the "cost curve" of health care spending is a priority in health reform, to ensure soaring costs don"t become unsustainable. Douglas Elmendorf, the director of the Congressional Budget Office, told lawmakers yesterday that bills proposed by the Senate health committee and the House leadership do the opposite: "The curve is being raised" (Montgomery and Murray, 7/17). "In the legislation that has been reported, we do not see the sort of fundamental changes that would be necessary to reduce the trajectory of federal health spending by a significant amount and, on the contrary, the legislation significantly expands the federal responsibility for health care costs," Elmendorf said, according to CQ Politics. Ways to reduce the rate of growth could include taxing employer-provided health benefits and reforming Medicare payments to reward cost effectiveness, rather than volume (Clarke and Epstein, 7/16). The Senate"s No. 2 Democrat, Richard Durbin, D-Ill., retorted that Elmendorf has "taken unrealistic positions" on the health care debate, and has failed to score important cost savings from measures for things like preventive care, the Wall Street Journal reports. "It"s been really hard to work with them." Meanwhile, the Republican leadership embraced Elmendorf"s comments. "The director of the Congressional Budget Office confirmed today what we have been saying for weeks: The health-care-spending plan that some are trying to rush through Congress would actually make things worse," said Senate Minority Leader Mitch McConnell (Boles, 7/16). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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