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Phase III Trial Shows Addition Of A New Agent Causes Big Reduction In Nausea And Vomiting After Chemotherapy
Chemotherapy-induced nausea and vomiting (CINV) remains a clinical management problem after treatment with highly emetogenic chemotherapy (HEC)*. A study has shown that the addition of a third drug (casopitant mesylate/CM) to a conventional two-drug regimen (dexamethasone and ondansetron) causes a big reduction in CINV events. The findings are reported in an Article published Online First and in the June edition of The Lancet Oncology, written by Professor Steven Grunberg, University of Vermont, Burlington, VT, USA, and colleagues.

Alzheimer's Disease: Disclosing Genetic Risk Does Not Cause Psychological Distress
Researchers from Boston University School of Medicine (BUSM) have shown that disclosing genetic risk information to adult children of patients with Alzheimer"s disease (AD) who request this information does not result in significant short-term psychological distress. The report from the REVEAL Study*, which appears in the July 16 issue of the New England Journal of Medicine, is the first randomized trial to disclose to participants whether or not they carried the íµ4 variant of the APOE gene, a variant that has been found to increase the risk of developing AD. The study demonstrated that test-related distress was reduced among those who learned that they were APOE íµ4 negative, and was only transiently increased among those who learned they were APOE íµ4 positive. The study also showed that persons with high levels of emotional distress before undergoing genetic testing were more likely to have emotional difficulties after disclosure.
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Scientists Bring TB Treatment Into The 21st Century, Scotland
A blueprint for a much-needed new generation of tuberculosis (TB) treatment has been developed by a team of scientists led at the University of Strathclyde in Glasgow.
Medical Devices

COAG Should Maintain Focus On Improving Indigenous Health, Australia

Tomorrow"s Council of Australian Governments (COAG) meeting is a crucial opportunity to focus on achieving concrete long-term health improvements for Indigenous people, the AMA said. The Council of Australian Governments (COAG) will meet in Darwin tomorrow (Thursday) to discuss a strategic national plan for closing the life expectancy gap between Indigenous and non-Indigenous Australians. AMA Federal President, Dr Andrew Pesce, said it is important that governments develop a national plan for Indigenous health in genuine partnership with Indigenous people and health organisations that know what is needed and what will work. "The Prime Minister has acknowledged that closing the 17-year life expectancy gap between Indigenous and non-indigenous Australians is one of the most significant challenges facing Australia," Dr Pesce said. "The recent commitment of $1.6 billion through COAG to Indigenous health is a very promising start to tackling this challenge. "COAG has a responsibility to ensure that this money is used to achieve real and concrete health outcomes for Indigenous people, and isn"t simply soaked up by Commonwealth and State bureaucracies at the expense of services on the ground." Dr Pesce said a priority for a strategic national plan for Indigenous health should be to improve workforce capacity by training more Indigenous doctors and health care workers. "It should also strengthen the capacity of mainstream health services to provide culturally appropriate primary care for Indigenous people. "COAG"s strategic national plan should contain clear targets and benchmarks for concrete action and health outcomes, and all governments should make a commitment to achieving them," he said. Australian Medical Association


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