Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Rogaine 3 pack Regular Strength
Popular Articles

Four New Targets For Breast Cancer Identified By Researchers
Four suspects often found at the scene of the crime in cancer are guilty of the initiation and progression of breast cancer in mice that are resistant to the disease, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the June edition of Cancer Cell.

New Study Shows Coaching To Patient Activation Levels Improves Disease Management Outcomes
People with chronic health conditions who receive coaching tailored to their level of health activation showed significant improvements in clinical outcomes, and experienced fewer hospitalizations and visits to the emergency room than those coached using traditional methods, according to a study published in the June issue of The American Journal of Managed Care.
News of the day
More Intensive Glucose Control In Type 2 Diabetes Reduces Heart Attacks And Heart Disease Events
A meta-analysis of five trials has shown that more intensive glucose control in type 2 diabetes leads to fewer heart attacks and heart disease events - but has no significant effect on stroke or mortality from all causes. The findings are reported in an Article in this week"s diabetes special issue of The Lancet, written by Dr Kausik Ray, University of Cambridge, UK, and colleagues.
Cardiovascular

Deet, The Popular Insect Repellent, Found To Be Neurotoxic

The active ingredient in many insect repellents, deet, has been found to be toxic to the central nervous system. Researchers writing in the open access journal BMC Biology say that more investigations are urgently needed to confirm or dismiss any potential neurotoxicity to humans, especially when deet-based repellents are used in combination with other neurotoxic insecticides. Vincent Corbel from the Institut de Recherche pour le Dē©veloppement in Montpellier, and Bruno Lapied from the University of Angers, France, led a team of researchers who investigated the mode of action and toxicity of deet (N,N-Diethyl-3-methylbenzamide). Corbel said, "We"ve found that deet is not simply a behavior-modifying chemical but also inhibits the activity of a key central nervous system enzyme, acetycholinesterase, in both insects and mammals". Discovered in 1953, deet is still the most common ingredient in insect repellent preparations. It is effective against a broad spectrum of medically important pests, including mosquitoes. Despite its widespread use, controversies remain concerning both the identification of its target sites at the molecular level and its mechanism of action in insects. In a series of experiments, Corbel and his colleagues found that deet inhibits the acetylcholinesterase enzyme - the same mode of action used by organophosphate and carbamate insecticides. These insecticides are often used in combination with deet, and the researchers also found that deet interacts with carbamate insecticides to increase their toxicity. Corbel concludes, "These findings question the safety of deet, particularly in combination with other chemicals, and they highlight the importance of a multidisciplinary approach to the development of safer insect repellents for use in public health". Notes: Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet Vincent Corbel, Maria Stankiewicz, Cedric Pennetier, Didier Fournier, Jure Stojan, Emmanuelle Girard, Mitko Dimitrov, Jordi Molgo, Jean Marc Hougard and Bruno Lapied BMC Biology (in press) Article available at journal website: http://www.biomedcentral.com/bmcbiol/ Graeme Baldwin BioMed Central


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009