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Phase III Trial Shows Addition Of A New Agent Causes Big Reduction In Nausea And Vomiting After Chemotherapy
Chemotherapy-induced nausea and vomiting (CINV) remains a clinical management problem after treatment with highly emetogenic chemotherapy (HEC)*. A study has shown that the addition of a third drug (casopitant mesylate/CM) to a conventional two-drug regimen (dexamethasone and ondansetron) causes a big reduction in CINV events. The findings are reported in an Article published Online First and in the June edition of The Lancet Oncology, written by Professor Steven Grunberg, University of Vermont, Burlington, VT, USA, and colleagues.

First Genetic Evidence For Why Placebos Work Presented By UCLA Scientists
Placebos are a sham - usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.
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Genomic Health's Oncotype DX(R) Colon Cancer Test Predicts Individualized Recurrence Risk For Stage II Colon Cancer Patients
Genomic Health, Inc. (Nasdaq: GHDX) announced positive results from the landmark QUASAR validation study, which demonstrated that the Oncotype DX(R) colon cancer test can independently predict individual recurrence risk in stage II colon cancer patients following surgery. Importantly, the Oncotype DX colon cancer Recurrence Score(R) provided additional independent clinical value beyond standard measures. The study showed that the colon cancer Recurrence Score maintained significance (p=0.008), independent of mismatch repair (MMR), also known as MSI (Microsatellite Instability), T-stage, nodes examined, grade and lymphovascular invasion.
Cardiovascular

Governments Should Increase Efforts To Reduce Stigma, Improve Access To HIV Services Among MSM, UNAIDS Executive Director Sidibe Says

Governments worldwide should take action to eliminate stigma and discrimination against men who have sex with men, women who have sex with women and transgender people and improve their access to HIV services, UNAIDS Executive Director Michel Sidibe said recently, the Stabroek News reports. Sidibe added that governments also should create social and legal environments that respect human rights and ensure universal access to HIV prevention and treatment.According to the News, Sidibe in the statement said that the "failure to respond effectively has allowed HIV to reach crisis levels in many communities of men who have sex with men and transgender people." Efforts to reverse the spread of the virus among vulnerable populations must be evidence-based, grounded in human rights and support efforts to decriminalize same-sex sexual contact, he added, noting that more than 80 countries prohibit same-sex behavior. According to the News, UNAIDS and the United Nations Development Program have launched a campaign that aims to increase access to HIV services among MSM and transgender populations. UNAIDS estimates that in some regions HIV prevalence among MSM is more than 20 times higher than among the general population. In addition, HIV prevention services only reach 10% to 30% of MSM, the News reports. The UNAIDS plan outlines several factors that hinder access to HIV services for MSM, including an unwillingness of governments and donors to invest in services for MSM and fear of stigma and discrimination. Paul De Lay, deputy executive director of UNAIDS, said, "Countries must be rigorous in monitoring the evolution of their epidemics and recalibrate their HIV programming to respond to the needs of those most at risk," adding that programs targeting MSM "must be based on local epidemiological and social realities to be effective" (Stabroek News, 5/17). Reprinted with kind permission from http://www.kaisernetwork.org. You can view the entire Kaiser Daily Health Policy Report, search the archives, or sign up for email delivery at http://www.kaisernetwork.org/dailyreports/healthpolicy. The Kaiser Daily Health Policy Report is published for kaisernetwork.org, a free service of The Henry J. Kaiser Family Foundation. © 2009 Advisory Board Company and Kaiser Family Foundation. All rights reserved.


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