Popular Articles

Toronto Star Columnist Examines Polio Eradication In India
According a Toronto Star column, it is an "enormous challenge" for India"s government to try to get all of its citizens immunized against polio. "It has used everything from elephants and camels to rickety boats and bikes to ferry the vaccine to remote regions where temperatures have topped 40C the past three months. The polio serum needs to be kept at a temperature below 8C. Its efforts have not all been in vain: the number of new cases in the country last year was 559, down from 200,000 in the early 1980s," writes columnist Rick Westhead.

Video Can Help Patients Make End-Of-Life Decisions
Viewing a video showing a patient with advanced dementia interacting with family and caregivers may help elderly patients plan for end-of-life care, according to a study led by Massachusetts General Hospital (MGH) researchers. In their report in the journal BMJ, released online, the investigators find that participants who watched such a video in addition to listening to a verbal description of the condition were more likely to indicate they would choose only comfort care if they developed advanced dementia and also said they felt the video was helpful to their decision-making process.
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Chronic Kidney Disease Profoundly Impacts Quality Of Life
Chronic kidney disease (CKD) can significantly lessen patients" quality of life, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Certain types of patients women, diabetics, and those with a history of heart complications are most affected. These findings indicate that medical care for CKD patients should include strategies to lessen the negative impact of CKD on quality of life.
Cardiovascular

Hormone Levels Contribute To Stress Resilience

It is important to understand what biological mechanisms contribute to an individual"s capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters. Dr. Charles A. Morgan III and his colleagues from Yale University and the VA National Center for PTSD have worked closely with collaborators at the Special Forces Underwater Warfare Operations Center to study special operations soldiers enrolled in the military Combat Diver Qualification Course (CDQC). Dehydroepiandrosterone, or "DHEA" as it is commonly known, is a hormone that is secreted by the adrenal gland in response to stress. Although medical scientists have known for over a decade that DHEA provides beneficial, anti-stress effects in animals, they did not know until now whether this was also true for humans. The scientists completed psychological and hormone assessments on a group of soldiers the day before they began the month-long CDQC, and immediately after their final pass/fail exam - a highly stressful, nocturnal, underwater navigation exercise. They found that soldiers with more DHEA performed better during the final underwater navigation exam than those with less DHEA. These findings are being published by Elsevier in the August 15th issue of Biological Psychiatry. Underwater navigation is a task that relies on an area of the brain called the hippocampus that is very sensitive to the negative effects of stress. "Animal studies have shown that DHEA buffers against stress, in part, by modulating receptors in this region of the brain," explained Dr. Morgan. "These findings are important in understanding why and how soldiers may differ in their ability to tolerate stress and also raise the possibility that, in the future, compounds like DHEA might be used to protect military personnel from the negative impact of operational stress." Clearly, additional research is still needed but these findings are a step forward in the quest to help prevent or better treat the symptoms of stress-related disorders that these high-risk individuals experience. Notes: The article is "Relationships Among Plasma Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate, Cortisol, Symptoms of Dissociation, and Objective Performance in Humans Exposed to Underwater Navigation Stress" by Charles A. Morgan III, Ann Rasmusson, Robert H. Pietrzak, Vladimir Coric, and Steven M. Southwick. Authors Morgan, Pietrzak, Coric, and Southwick are affiliated with the Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut. Morgan, Pietrzak, and Southwick are also with the National Center for PTSD, VA CT Healthcare System, West Haven, Connecticut. Rasmusson is from the Department of Psychiatry, Boston University, and the National Center for PTSD, VA Boston Healthcare System, in Boston, Massachusetts. The article appears in Biological Psychiatry, Volume 66, Issue 4 (August 15, 2009), published by Elsevier. Jayne Dawkins Elsevier


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