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Antibodies That May Prevent Disease
Antibodies to a wide range of substances that can aggregate to form plaques, such as those found in Alzheimer"s patients, have been identified in the blood and cerebrospinal fluid of healthy people. Levels of these antibodies decline with age and, in Alzheimer"s patients, with increasing progression of the disease.

QRISK® - New Heart Disease Risk Score Outperforms Existing Test
An independent external validation of QRISK® (http://www.qrisk.org) - a new score for predicting a person"s risk of heart disease - has shown that it performs better than the existing test and should be recommended for use in the United Kingdom by the National Institute for Health and Clinical Excellence (NICE).
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Adopting Low-Risk Dietary And Lifestyle Factors Related To Lower Incidence Of High Blood Pressure
Adherence to modifiable lifestyle and dietary factors including maintaining normal weight, daily vigorous exercise, eating a diet high in fruits, vegetables, low-fat dairy products and low in sodium and taking a folic acid supplement was associated with a significantly lower incidence of self-reported hypertension among women, according to a study in the July 22/29 issue of JAMA.
Nutrition

Linus Pauling Prize For Health Research Won By Vitamin D Expert Dr. Michael Holick

Dr. Michael Holick, a professor of medicine, physiology and biophysics at the Boston University School of Medicine who has revolutionized the understanding of vitamin D and its role in disease prevention, has received the $50,000 Linus Pauling Institute Prize for Health Research. The prize was presented at a biennial conference, Diet and Optimum Health, sponsored by the Linus Pauling Institute at Oregon State University. It recognizes international leaders in research on the role of diet and nutrition in health promotion and disease prevention, as well as efforts to disseminate knowledge on diet, lifestyle and health to enhance public health and reduce suffering from disease. Holick is responsible for redefining vitamin D deficiency, a concern that"s now seen as a national epidemic, and has been strongly criticized in the past 20 years when warning that abstinence from direct sun exposure through sunblock use was leading to increasing vitamin D deficiency - with serious implications for cancer and other diseases. "I well remember Linus Pauling standing up to criticism and skepticism, a trait of Holick as well," said Nevin Scrimshaw, president of the International Nutrition Foundation, in nominating him for this award. "Today, Holick is recognized as a world renowned nutritional biochemist/physician whose research has had a global impact on the health of both children and adults." Holick"s work opened a wide field of investigation that has now demonstrated how vitamin D deficiency increases the risk of cancer, autoimmune diseases, infectious and cardiovascular disease, Scrimshaw said. And studies have concluded that more than 50 percent of the children and adults in the United States are vitamin D deficient - a growing crisis, due in part to successful campaigns to always wear sun protection outdoors and reduce natural production of what"s known as the "sunshine vitamin." Holick was the first scientist to isolate the active forms of vitamin D, and in the past three decades has become the world authority on photobiology of vitamin D through synthesis in the skin. He"s determined that anyone living north of 35 degrees latitude can"t make enough vitamin D in the skin during winter exposure to sunlight. His work has helped lead to vitamin D fortification in various foods. In more recent work, Holick has shown links between vitamin D deficiency and the development of preeclampsia in pregnancy. An understanding of the health benefits of vitamin D was cited by Time magazine as one of the top 10 medical advances in 2007. The prize is named after Linus Pauling, a two-time Nobel laureate, OSU alumnus, founder of the Linus Pauling Institute and pioneer in the role of vitamins and micronutrients in promoting health and preventing disease. Balz Frei Oregon State University


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