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Alzheimer's Disease: Disclosing Genetic Risk Does Not Cause Psychological Distress
Researchers from Boston University School of Medicine (BUSM) have shown that disclosing genetic risk information to adult children of patients with Alzheimer"s disease (AD) who request this information does not result in significant short-term psychological distress. The report from the REVEAL Study*, which appears in the July 16 issue of the New England Journal of Medicine, is the first randomized trial to disclose to participants whether or not they carried the íµ4 variant of the APOE gene, a variant that has been found to increase the risk of developing AD. The study demonstrated that test-related distress was reduced among those who learned that they were APOE íµ4 negative, and was only transiently increased among those who learned they were APOE íµ4 positive. The study also showed that persons with high levels of emotional distress before undergoing genetic testing were more likely to have emotional difficulties after disclosure.

MU Public Health Program Receives Grant To Combat Human Trafficking
After drug dealing, trafficking of humans is tied with arms dealing as the second largest criminal industry in the world, and it is the fastest growing, according to the U.S. Department of Health and Human Services (HHS). Recently, HHS awarded more than $2 million in grants to state and local organizations, including the University of Missouri, to identify and help victims of human trafficking.
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Discovery Of Breast Cancer Gene That's Blocked By Blood Pressure Drug
Researchers have identified a gene that is overexpressed in up to 20 percent of breast cancers and that could be blocked in the lab by a currently available blood pressure drug, according to a new study from the University of Michigan Comprehensive Cancer Center.
Mental Health

Parkinson's Disease As A Risk Factor For Compulsive Gambling And Impulse Control Disorders

There is also increasing knowledge about higher frequency of compulsive behavior in patients with PD compared to the general population. "These impulse control disorders such as pathological gambling, hyper-sexuality, compulsive shopping, compulsive eating or compulsive overuse of dopaminergic drugs can lead to monetary losses or worsen social handicap of PD patients," Professor Bassetti explains. A current study from the Czech Republic being presented at the ENS meeting in Milan compared 20 patients with PD manifested before age 45 with 20 control subjects. A computer version of the Iowa Gambling Task (IGT) was used for testing. Patients with PD showed a significantly lower IGT-score - defined as the difference between a number of advantageous and disadvantageous choices - compared with the control group. "It is necessary to consider pathological gambling in young Parkinson patients with regards to their treatment and possible clinical and sociological outcomes", the researchers concluded. European Neurological Society


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