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A Rush Of Blood To The Head - Anger Increases Blood Flow
Mental stress causes carotid artery dilation and increases brain blood flow. A series of ultrasound experiments, described in BioMed Central"s open access journal Cardiovascular Ultrasound, also found that this dilatory reflex was absent in people with high blood pressure.

National Cancer Institute Research Identifies Unique Mechanism Of Brostallicin's Anti-Tumor Effectiveness
Cell Therapeutics (CTI) (Nasdaq and MTA: CTIC) announced that researchers from the Laboratory of Molecular Pharmacology at the National Cancer Institute presented new preclinical research identifying unique anti-tumor mechanisms of brostallicin that sets this agent apart from other currently used chemotherapy agents. CTI acquired worldwide rights to brostallicin when it acquired privately-held Systems Medicine LLC in 2007. Published in the journal Molecular Cancer Therapy (Mol Cancer Ther 2009;8(7) July 2009; 1985-94), the researchers utilized preclinical studies to provide clues into tumor susceptibility mechanisms for brostallicin, a synthetic DNA minor grove binder, and to identify differences between brostallicin and trabectedin (Yondelis(R); ET-743), which is a natural marine product approved in Europe. Unlike other chemotherapy agents, including trabectedin, the NCI research indicates that the tumor cell DNA damaging effects of brostallicin are enhanced by high tumor glutathione levels, a hallmark of drug-resistant tumors. Brostallicin was shown to affect DNA in both dividing and quiescent cells. Its actions can be followed by induction of a specific DNA binding protein foci that can be detected in circulating blood cells. Importantly, brostallicin was active in a trabectedin-resistant cell line.
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Controling Concurrent Hepatitis B Infection By Focusing HIV Treatment
Prolonged use of highly active antiretroviral therapy (HAART) to treat people infected with both HIV and hepatitis B (HBV) helps to better control the hepatitis B infection and could delay or prevent liver complications, according to a new study by researchers at Wake Forest University School of Medicine.
Medical Devices

President Obama Releases Statement, Video Urging U.S. Residents To Get Tested For HIV

President Obama on Saturday released a statement marking National HIV Testing Day that urged U.S. residents to get tested for HIV and work toward reducing the spread of the virus, Bloomberg/Arizona Daily Star reports (Bloomberg/Arizona Daily Star, 6/28). Obama said in the statement, "Each of us must take responsibility for reducing our risk of acquiring or transmitting HIV and for supporting affected individuals and communities. This means getting tested for HIV and working to end the stigma and discrimination people living with HIV face." The White House also released a video message with Obama"s statement (White House release, 6/27). This information was reprinted from dailyreports.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily U.S. HIV/AIDS Report, search the archives and sign up for email delivery at dailyreports.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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