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Ex-Child Soldiers: From Victims Of War To Protagonists Of Peace
Two young people, former child soldiers, who have transformed their brutal life experiences toward helping the more than one billion children whose lives are currently touched by war today told the international community, including Franco Frattini, the Italian Minister of Foreign Affairs, and Giovanni Alemanno, Mayor of Rome, what must be done to ensure that children are fully protected even in the heat of war.
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Health Care Overhaul Could Include Changes To Doctor Payments
The Wall Street Journal reports that "Democratic centrists said they won a tentative commitment from the White House to back a proposal to curb the growth of Medicare costs. ... One proposal pushed both by President Barack Obama and some centrists is to give the executive branch the authority to implement cuts to Medicare spending that would be recommended by independent experts. Congress could stop the cuts, but only if it acted swiftly. Fiscal conservatives say that under the current system, which gives Congress more power, lawmakers shy away from politically tough votes to restrain Medicare costs."
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Cell Self Digestion Pathway Is Mechanism Behind Cancer Tumor Suppression
"Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.
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Quintiles Consulting Outlines Methods For Re-Balancing Drug Development Risks

Quintiles Consulting released the first in a three-part series of white papers addressing how best to navigate risk in drug development. The first paper, "On the Re-Balancing of Risk to Transform Cost and Productivity in Drug Development," focuses on operational risk. It is available for download at http://www.quintiles.com/consulting. Biopharmaceutical companies are facing unprecedented challenges in their efforts to bring new medicines to market to meet the needs of patients. Drug development costs are soaring - requiring on average nearly $1 billion and 17 years to bring a compound to market. It is well recognized in the industry that traditional cost-cutting and methods to improve productivity have been exhausted. "This new environment calls for novel risk-based solutions," said Adrian McKemey, Quintiles Consulting practice leader for product development and commercialization. "We are applying new business models to help companies rebalance, share and hedge their risk - transforming the traditional approach to development. The new risk-based approaches focus on ways to circumscribe, share, rebalance and hedge drug development risk to transform cost and productivity. "We are seeing risk being evaluated through three distinct lenses - operational risk, portfolio risk and re risk," McKemey said. The models outlined in the paper challenge and redistribute the traditional boundaries of the pharmaceutical business model, i.e., what a pharmaceutical company must own to capture competitive advantage and to grow, and what can be factored out and hedged by partnering with external s. The next paper in this series will focus on portfolio risk mitigation. To receive this paper or to learn more about Quintiles Consulting visit our website at http://www.quintiles.com/consulting. The authors: Adrian McKemey is a Managing Director with Quintiles Global Consulting (QGC) and leads the Product Development and Commercialization Practice. Badhri Srinivasan leads the Enterprise Transformation Unit - an organization dedicated to mining the experiences accumulated over 10,000 clinical trials to identify systematic issues and solutions increased speed and reduce cost and variance in clinical development. Peter Payne leads efforts on assessing, mitigating and pricing asset and clinical development risk to support risk sharing initiatives at the portfolio, operational and re level. About Quintiles Consulting Quintiles Consulting works with pharmaceutical, biotech and medical device companies to maximize potential and minimize risk, from discovery through development and commercialization by providing expert strategic, operational, and technical advice. Building on the global reach and expertise of Quintiles Transnational, Quintiles Consulting practice areas include Product Development and Commercialization, Regulatory and Quality, and Market Access, and Eidetics. Quintiles Consulting has full-time consultants based across the U.S. and Europe to serve its global clients. For more information, please visit http://www.quintiles.com/consulting. Quintiles


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