Cardiovascular
In today"s health environment, harmful cold and flu strains can travel the globe and pose serious risk to young children. And, at the same time, the FDA has issued warnings about administering over-the-counter cough and cold medications to children under the age of four. Parents of young children are in a quandary as to how to keep their kids safe and healthy. Many are embracing preventative measures to improve their child"s immune system and ward off illness.
When doctors are managing care for women with breast cancer, the information available to them profoundly influences the type of care they recommend. Knowing whether a woman"s cancer has metastasized, for instance, directly affects how her doctors will approach treatment -- which may in turn influence the outcome of that treatment.
The Medical Protection Society (MPS) welcomes the Court of Appeal decision that NHS hospital doctors have the right to legal representation at disciplinary hearings, where serious charges are raised. The ruling gives doctors a contractual right to legal representation by a lawyer instructed by a medical defence organisation (MDO).
As part of its continuing efforts to help physicians learn about and adopt new technology, the American Medical Association (AMA) announced a new, free webinar series that will help physicians understand the health information technology (HIT) provisions laid out in the recently passed economic stimulus bill. The three-part series will lay out what these provisions mean for physicians and how they can take advantage of the $19 billion in funds allocated for the purchase and use of HIT. The first webinar is Thursday, May 21.
The following summarizes selected women"s health-related blog entries. ~ "Mainstream Media Reinforces Unexamined Arguments Against Public Funding for Abortion," Amanda Marcotte, RH Reality Check: It "seems that mainstream media s ... believe that abortion is an effective cudgel to beat health care reform to death," Marcotte writes. According to Marcotte, the "unvarnished truth" is that there is "no way that any kind of public health care plan will have elective abortion coverage. Nor is there any real chance of abortion becoming mandated coverage." However, "you wouldn"t know it to read the media coverage of this issue," she writes, continuing that "we"ve got the toxic mixture of pants-on-fire lying anti-choicers and cowardly media outlets that give the opponents of health care reform an opportunity to lie about the potential for taxpayer-funded abortions." Those who defend health care reform are "so busy trying to shut down the misinformation about abortion coverage that we"re not having the more interesting discussion about whether or not abortion should be covered," Marcotte says. She adds, "And by not having that discussion, we"re allowing the belief that some people"s moral objections to abortion should dictate federal policy lay unchallenged," she continues. She writes that she "suspect[s] that anti-choicers latched onto taxpayer-funded abortions because they can count on a lot of the public to imagine the government funding female licentiousness." Marcotte concludes that the "good news is that this contempt for female sexuality has receded enough that the media debate hasn"t -- yet -- turned to whether or not health care reform should cover contraception" (Marcotte, RH Reality Check, 7/28).~ "Privileging Opposition to Abortion," Jamison Foser, Media Matters for America: Some reporters "have skewed their reports in favor of those who oppose" coverage of abortion in federally subsidized insurance plans, according to Foser. For example, Foser writes that on a recent episode of MSNBC"s "Hardball," host Chris Matthews asked Sens. Richard Durbin (D-Ill.) and Orrin Hatch (R-Utah) "leading questions that encouraged them to state their opposition to insurance coverage of abortion" but never asked them "one simple question: Why shouldn"t abortion be covered, given that the procedure is legal?" Foser adds, "Nor has he asked if there are any other legal procedures that shouldn"t be covered." The "premise that taxpayers who oppose abortion shouldn"t have to pay for them with their tax money carries obvious implications the media ignores," Foser writes. He adds that the "idea that taxpayers shouldn"t pay for insurance that covers medical services they don"t support is fundamentally incompatible with the very concept of insurance." He continues, "If every interest group wields veto power over the medical care insurance can cover, insurance simply can"t work." However, this is not the "only logical inconsistency on the part of abortion foes that the media fail to examine" in their coverage of abortion issues in the health reform debate, he writes. "Many of those who are most adamant that the government not allow abortion to be paid for by health insurance plans are the same conservatives who argue against health care reform by warning of the prospect of a government bureaucrat getting between you and your doctor," according to Foser. He continues that the "same people who want a government ban on insurance coverage for a legal medical procedure turn around and demagogue about government bureaucrats making medical decisions," which is "a pretty obvious inconsistency, the kind any reporter should be able to spot easily." However, the "tension between those two positions has gone unexplored in news reports about the abortion controversy," Foser concludes (Foser, Media Matters for America, 7/24).~ "Obama Abortion Backtrack Shows He"s All Rhetoric, No Fight," Bonnie Erbe, U.S. News & World Report"s "Thomas Jefferson Street": "[O]ne thing we know will not be incl
Lawmakers are considering two new taxes to help pay for a health care overhaul: a tax on fatty foods and taxing insurers on so-called Cadillac plans. Both proposals were scrutinized in news articles.
The Washington Post tells the story of Danny Watt, who drowned in April 2008 after a lifelong struggle with mental health. Watt had a dual diagnosis: a serious mental illness along with abuse of drugs or alcohol.
Small business and medical groups are debating the health care overhaul proposals that could change their business models.
The nation"s struggles with physician and nurse shortages are evident as health care reform takes shape.
Ventana Biotech Inc ("Ventana")(PINK SHEETS:VNTA), a biotechnology company that is developing a appetite-suppressing chewing gum, released detailed information about its innovative Anti-Obesity Chewing Gum.
The Illinois attorney general on Thursday filed a lawsuit against the Center for AIDS Prevention for unlawful fundraising and falsifying official documents, ProPublica reports (Weaver, 7/27). Attorney General Lisa Madigan said the state revoked the organization"s registration 20 years ago, but its director, Steve Neely, also known as Morrell Neely, has continued to solicit donations in the state. "The state says the group tried to reregister as a nonprofit using a phony Chicago address, though its boss, ò€¦ lives in Riverside, Calif.," Courthouse News Service reports (Freeland, 7/27). "If the suit is successful, Illinois could seize money illegally raised there, bar Neely and others involved with the center from future charitable work in the state, freeze their assets, force them to pay back donations they may have "misused and/or wasted" with interest, and attempt to shut the group down for good by revoking its corporate status," ProPublica reports (7/27).
E-mail, search engines, smart phones and other new technologies that can disseminate new medical information quickly led to an almost immediate change in clinical practice for drug-eluting stents, according to a study reported in Circulation: Cardiovascular Quality and Outcomes.
Georgia has received $63.9 million in Ryan White Program grants to fund treatment and other services for people living with HIV, the Atlanta Journal-Constitution reports. Grant recipients include county health departments and community organizations. The funding will be used to provide outpatient health services, health insurance coverage and support services, such as transportation and housing. According to the Journal-Constitution, more than $1.79 billion in Ryan White funding was allocated nationwide. Several HIV/AIDS organizations said that the funding is necessary to continue providing services for people living with the disease. Tracy Elliot, executive director of AID Atlanta, said that the funding is "critical," noting that more than 18,000 HIV/AIDS cases have been reported in Georgia. He continued, "We would have a lot of deaths without [the funding]. There would be significantly more illnesses without it and significantly more transmission of the disease without it." According to Elliot, "[m]edical treatment and medications are of no value if people cannot have access to them" (Poole, Atlanta Journal-Constitution, 5/19).
Researchers at The University of Queensland have helped identify genes that could hold the key to treating a common and deadly type of breast cancer.
Hoag Memorial Hospital Presbyterian announced promising data from a clinical study showing patient-specific cancer vaccines derived from patients" own cancer cells and immune cells were well tolerated and resulted in impressive long-term survival rates in patients with metastatic melanoma whose disease had been minimized by other therapies.
Governments worldwide should take action to eliminate stigma and discrimination against men who have sex with men, women who have sex with women and transgender people and improve their access to HIV services, UNAIDS Executive Director Michel Sidibe said recently, the Stabroek News reports. Sidibe added that governments also should create social and legal environments that respect human rights and ensure universal access to HIV prevention and treatment.According to the News, Sidibe in the statement said that the "failure to respond effectively has allowed HIV to reach crisis levels in many communities of men who have sex with men and transgender people." Efforts to reverse the spread of the virus among vulnerable populations must be evidence-based, grounded in human rights and support efforts to decriminalize same-sex sexual contact, he added, noting that more than 80 countries prohibit same-sex behavior. According to the News, UNAIDS and the United Nations Development Program have launched a campaign that aims to increase access to HIV services among MSM and transgender populations. UNAIDS estimates that in some regions HIV prevalence among MSM is more than 20 times higher than among the general population. In addition, HIV prevention services only reach 10% to 30% of MSM, the News reports. The UNAIDS plan outlines several factors that hinder access to HIV services for MSM, including an unwillingness of governments and donors to invest in services for MSM and fear of stigma and discrimination. Paul De Lay, deputy executive director of UNAIDS, said, "Countries must be rigorous in monitoring the evolution of their epidemics and recalibrate their HIV programming to respond to the needs of those most at risk," adding that programs targeting MSM "must be based on local epidemiological and social realities to be effective" (Stabroek News, 5/17).
The Cambodian Ministry of Health has begun training primary education teachers in 12 provinces on HIV/AIDS prevention education, the Phnom Penh Post reports. Health officials said that although children in primary school are not seen as a high-risk population, they need to be educated on the disease. Mean Chhi Vun -- director of the National Center for HIV/AIDS, Dermatology and STDs -- said the students "are a group of people we have to pay attention to because they ... will be the backbone of the nation." Secondary-school aged students currently are receiving HIV/AIDS education, and the programs are being used as a model for the new primary school initiative, according to Pen Saroeun, director of the Ministry of Education"s School Health Department. Some health officials have said that young people are becoming increasingly at risk for HIV, and most outreach efforts target commercial sex workers and their clients and not young people, the Post reports. Saroeun noted that the HIV/AIDS prevention education program has been successful in secondary schools and is the reason the ministry decided to launch the program in primary schools, adding that many students drop out before reaching secondary school. He said, "We will teach them basic knowledge about HIV/AIDS and life skills, such as negotiation skills, how to say "no," goal setting, and how to provide care and support to people living with HIV/AIDS." The ministry plans to double the $100,000 it allocated to HIV/AIDS education spending last year with additional funding from the United Nations Population Fund, according to Saroeun. He added, "If we are successful in those 12 provinces, then we will do it in the other provinces" (Kunthear, Phnom Penh Post, 5/19).
Concerns are being raised by a growing number of British academics that bureaucratic overload is stifling their ability to undertake clinical research, compromising the future of this activity in the UK, and ultimately doing patients a disservice. The issues are discussed in a Special Report in the August edition of The Lancet Oncology, written by freelance journalist Adrian Burton.
QuatRx Pharmaceuticals Company, a privately-held biopharmaceutical company, announced positive top-line efficacy results from the first of two patient cohorts in its second pivotal Phase 3 trial of the investigational compound, Ophena(TM) (ospemifene tablets), for the treatment of postmenopausal vulvovaginal atrophy (VVA). The Company has also successfully completed two long term safety extension studies from its first pivotal Phase 3 studies. QuatRx intends to use these results in support of a New Drug Application (NDA) with the U.S. Food and Drug Administration (FDA) in early 2010 seeking approval for Ophena(TM), a new SERM (selective estrogen receptor modulator) for the treatment of the symptoms of vulvovaginal atrophy. Ophena(TM) is the only non-estrogen therapy currently in late-stage development for the treatment of vaginal symptoms associated with menopause.
Inhibiting an enzyme in the brains of newborns suffering from oxygen and blood flow deprivation stops a type of brain damage that is a leading cause of cerebral palsy, mental retardation and death, according to researchers at Cincinnati Children"s Hospital Medical Center.
A US study published online ahead of print in a leading medical journal suggests that complications from H1N1 swine flu could hit pregnant
"You can think of Congress"s efforts to pay for health reform as being a little bit like a battle to slay a many-headed Hydra," writes the New York Times" economic columnist, David Leonhardt. Congress has floated idea after idea for paying for comprehensive health reform, but their proposals have failed to make ends meet because they "do not raise revenue as quickly as health costs rise." Most new taxes - such as a surtax on the rich proposed in the House - increase only as quickly as the economy, while health costs have inflated much more quickly over the last decade.
"Three internationally known organizations based in St. Louis - the Donald Danforth Plant Science Center, the Washington University School of Medicine and St. Louis Children"s Hospital" - have entered into a partnership, known as the Global Harvest Alliance (GHA), which aims to "create inexpensive, nutritionally complete food to help the world"s hungry and undernourished," the AP/Google.com reports. Alliance researchers will focus on several of the most successful approaches used to combat malnutrition and attempt to further enrich foods already used to fight it. "In addition, the alliance aims to help testing and distribution of crops genetically modified to boost nutritional content. They hope to provide the crops cheaply to farmers to produce more nutritious foods," writes the AP/Google.com (Taylor, 7/29).
China Daily explores how a new anti-smoking initiative in China targets the country"s medical professionals. According to the newspaper, "China is the world"s largest tobacco producer and consumer," with "350 million smokers, plus 450 million people exposed to second-hand smoke." Annually, 1 million deaths are smoking-related, according to China"s Ministry of Health.
The Government of Japan will sign a new agreement with UNICEF tomorrow, making available $5.6 million (÷¥ 533 million or SDG 13.5 million) in support of health programmes that will benefit up to 5 million people in the coming year.
The Pittsburgh Post-Gazette profiled the Girlfriends Project, a domestic violence and HIV/AIDS education program implemented by the Pittsburgh AIDS Task Force that targets at-risk black women in three Allegheny County, Pa., cities. Blacks "comprise just 7 percent of the total population in southwestern Pennsylvania but 41 percent of those living with HIV/AIDS, according to Allegheny County Health Department statistics provided by the task force," the Post-Gazette reports. "The Girlfriends Project was designed for Braddock, Clairton and Duquesne "because we knew nobody was doing outreach there," project coordinator, Lisa Dukes, said. As part of the project, Dukes hosts Tupperware party-style gatherings in homes of residents where she provides HIV testing and education, sexual health information, safe sex products and cash gift cards. The project is an outgrowth of the CDC"s prevention program Sisters Informing Sisters About Topics on AIDS, or SISTA, and has been so successful that CDC "has asked the task force to introduce it at the CDC"s 2009 National HIV Prevention Conference in Atlanta Aug. 23," the article states (Smith, 7/29).
Although Hispanic women tend to develop breast cancer less than Caucasian women, it is usually more aggressive and advanced when it does develop.
The Royal Pharmaceutical Society has called for clarification of the responsible pharmacist requirements but will not be asking the Department of Health to amend the commencement date of the regulations.
Recycling is a critical component in the process of transmitting information from one neuron to the next, and a large protein called Tweek plays a critical role, said an international consortium of researchers led by Baylor College of Medicine in a report in the current issue of the journal Neuron.
Vystar Corporation and Alatech Healthcare, LLC announced 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market and sell the first exam gloves manufactured with Vytex® Natural Rubber Latex (NRL). Alatech plans to introduce exam gloves made with Vytex NRL in the near future.
Helicobacter pylori, nonsteroidal anti-inflammatory drug use and smoking are the most important risk factors for peptic ulcer. Alcohol intake may also play a role in the development of gastric ulcers. Psychological stress may also have an impact on the onset and course of ulcer disease. However, very little is known as to whether childhood adversities involving financial problems, conflicts in the family, problems with alcohol, and matters of personal security are associated with peptic ulcer.
A systematic literature review of mothers" experiences with bottle-feeding found that while mothers recognize the benefits of breastfeeding, those who bottle-feed with infant formula do not receive adequate information and support from their healthcare providers and thus, ultimately put their baby"s health at risk. "While it is important to promote breastfeeding," the authors conclude, "it is also necessary to ensure that the needs of bottle-feeding mothers are not overlooked."
[Why Great Britain"s success in Beijing could have been anticipated and why it should continue beyond 2012
Osteoarthritis (OA), the most common joint disorder throughout the world and a leading cause of disability, is characterized by pain, impaired joint mobility, reduction of muscular strength and loss of joint function. Unlike most other common diseases, little is known about its origins, and factors predicting a severe disease course have not been identified. A new study, the first to establish a laboratory marker for the risk of severe OA, found that vascular cell adhesion molecule 1 (VCAM-1), was a strong predictor of hip and knee joint replacement due to severe OA. The study was published in the August issue of Arthritis & Rheumatism .
Patients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of infection, due to both disturbances in their immune responses and treatment with immunosuppressive drugs. Because morbidity and mortality related to influenza are increased in immunocompromised patients, it is recommended that patients with SLE get annual flu shots, which are safe and do not increase disease activity. Both antibody and cell-mediated responses are involved in the immune response to influenza; in SLE, antibody responses to the vaccine are diminished, but it is not known if the same effect is seen in cell-mediated responses. A new study was the first to examine cell-mediated responses in SLE patients prior to and following influenza vaccination. The study was published in the August issue of Arthritis & Rheumatism .
Molecular Insight Pharmaceuticals, Inc. (NASDAQ: MIPI) announced that the European Medicines Agency (EMEA) has approved its Phase 3 protocol for Onalta (Yttrium-90 edotreotide). Onalta is the Company"s lead radiotherapeutic product candidate under development for the treatment of metastatic carcinoid and pancreatic neuroendocrine tumors in patients whose symptoms are not controlled by conventional therapy. The compound has shown the potential to selectively deliver lethal radiation to cancer cells. The proposed Phase 3 trial will confirm that administration of Onalta results in stabilization, regression or complete remission of the carcinoid tumor, and improves carcinoid-related symptoms when compared to a high-dose regimen of the current standard therapy for this disease, Sandostatin®. With EMEA"s approval of its proposed Phase 3 protocol in hand, Molecular Insight can proceed with the final clinical trial that will position Onalta for marketing authorization in the EU.
Registration is underway for the 10th International Conference on Systems Biology (ICSB). The conference will be held at Stanford University from August 30th - September 4th.
Memory is a fundamental function of nerve cells in the brain, and loss of memory is a key symptom in many people with Alzheimer"s disease.
U.S. Senators Mel Martinez (R-FL) and Herb Kohl (D-WI) of the Special Committee on Aging held a hearing to address the issue of transparency in physician-industry financial relationships. Among the hearing"s topics were the industry"s involvement in continuing medical education and its potential use as a method for promoting "off-label" prescribing. The senators heard from witnesses about different ways to achieve balance between appropriate industry involvement in continuing medical education while mitigating unethical and illegal promotion.
With an estimated 57 million Americans with pre-diabetes, the American Diabetes Association today launches My Health Advisor, an online tool that helps people understand their personal risk for developing type 2 diabetes, heart disease and stroke. My Health Advisor is available at http://www.CheckUpAmerica.org/MHA.
Stem Cell Therapeutics Corp. ("SCT" or the "Company") (TSX VENTURE:SSS) is pleased to announce the acceptance and publication of the paper entitled "Open labeled, uncontrolled pharmacokinetic study of single intramuscular hCG dose in healthy male volunteers" by the International Journal of Clinical Pharmacology and Therapeutics, Vol. 47, August 2009. This paper was authored by Drs. Alan Moore, President & CEO, Allen Davidoff, VP Product Development and Yan Yang, Clinical Research Associate, all of SCT; Dr. Michael D. Hill of Foothills Hospital at the University of Calgary, and Dr. Steven C. Cramer, from the University of California, Irvine.
AstraZeneca (NYSE: AZN) announced the company has submitted a New Drug Application to the U.S. Food and Drug Administration (FDA) and a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMEA) for an investigational drug, vandetanib 100 mg for use in combination with chemotherapy for the treatment of advanced non-small cell lung cancer in patients previously treated with one prior anti-cancer therapy. The U.S. and European submissions are supported by data from Phase III clinical studies evaluating the safety and efficacy of vandetanib 100 mg in combination with chemotherapy. Pending approval, the treatment will be marketed as ZACTIMA(TM).
An estimated 428,000 residents in New Mexico could lose their private, employer-based coverage if Congress passes a House health reform bill, according to state-specific analysis of The American Affordable Health Choices Act of 2009 released this week by The Heritage Foundation.
Chronic kidney disease (CKD) can significantly lessen patients" quality of life, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Certain types of patients women, diabetics, and those with a history of heart complications are most affected. These findings indicate that medical care for CKD patients should include strategies to lessen the negative impact of CKD on quality of life.
A researcher at The University of Western Ontario has received over $603,000 from the Canadian Institutes of Health Research (CIHR) to investigate how and why a group of bacterial toxins leads to the development of toxic shock syndrome and other serious diseases. John McCormick is an associate professor in the Department of Microbiology and Immunology at the Schulich School of Medicine & Dentistry, and a scientist with the Lawson Health Research Institute. His research is one of 18 projects at Western and Lawson to receive new CIHR operating grants totaling more than $9.55 million.
Thousands of scientists and hundreds of software programmers studying the process by which RNA inside cells normally degrades may soon broaden their focus significantly.
A new education programme has been developed to provide enhanced training in genetic technologies and clinical applications for healthcare scientists working in laboratory genetics, Health Minister Ann Keen announced.
Congress Needs To Think Big About Medicare Fix Politico
Prescribers treating patients who have had total hip or knee replacement surgery can access an independent review of the oral anticoagulant rivaroxaban (Xarelto) in the August issue of NPS RADAR.
Certainly there is strength in numbers, but only if those numbers can effectively communicate with one another. Now, a new study finds that administration of a novel small molecule which effectively disrupts a key bacterial communication process protects an animal host from infection. The research, published by Cell Press in the July 31st issue of the journal Molecular Cell, may lead to more effective treatments for bacterial infection that won"t encourage growth of treatment resistant bacteria.
Physicians can and should play a leading role in achieving health care reform by working towards comprehensive reform of the way health care is paid for and delivered, helping achieve a guaranteed 1.5 percent annual savings in health care costs that would pay for covering all Americans, according to a New England Journal of Medicine Perspective piece published online.
Scientists at Washington University School of Medicine in St. Louis have identified a substance in the liver that helps process fat and glucose. That substance is a component of the common food additive lecithin, and researchers speculate it may one day be possible to use lecithin products to control blood lipids and reduce risk for diabetes, hypertension or cardiovascular disease using treatments delivered in food rather than medication.
Pregnant women have a higher incidence of insufficient amniotic fluid levels (oligohydramnios) in the summer months due to dehydration, according to a study conducted by researchers at Ben-Gurion University of the Negev (BGU).
NHS staff will be vaccinated first in the Government"s swine flu vaccination campaign, followed by pregnant women, young children and adults with chronic illnesses, Pulse can exclusively reveal. Pulse has learned from a senior Government adviser that a "pecking order" has been drawn up for vaccination.
Patients with developmental disabilities such as Down syndrome or cerebral palsy will benefit from a new online learning activity launched today by The Royal Australian College of General Practitioners (RACGP) to assist GPs to navigate the complex area of developmental disability.
This month"s Ophthalmology, the journal of the American Academy of Ophthalmology, reports on the use of bevacizumab (Avastin) to benefit diabetic patients with macular edema as well as people who develop cystoid macular edema after cataract surgery. Bevacizumab is also used to treat some cancers. A third study describes methods that could make cataract surgery safer for diabetic retinopathy (DR) patients. DR is the major threat to vision in working-age people, a health issue that will only intensify if cases triple by 2050 as predicted.
Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) announced that the U.S. Food and Drug Administration (FDA) approved ONGLYZA™ (saxagliptin), a dipeptidyl peptidase-4 (DPP4) inhibitor. ONGLYZA is indicated as an adjunct to diet and exercise to improve blood sugar (glycemic) control in adults for the treatment of type 2 diabetes mellitus. ONGLYZA once daily can be used in combination with commonly prescribed oral anti-diabetic medications metformin, sulfonylureas or thiazolidinediones (TZD) or as a monotherapy to significantly reduce glycosylated hemoglobin (A1C) levels. ONGLYZA should not be used for the treatment of type 1 diabetes or for the treatment of diabetic ketoacidosis (high levels of certain acids, known as ketones, in the blood or urine). ONGLYZA has not been studied in combination with insulin.
Pfizer Inc (NYSE: PFE) and Medivation, Inc. (NASDAQ: MDVN) announced the initiation of a Phase 3 trial of the investigational drug dimebon (latrepirdine) in patients with Huntington disease. The international safety and efficacy trial, known as HORIZON, is designed to evaluate the potential benefits of dimebon on cognition (thinking and memory) in patients with Huntington disease. The companies also announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to dimebon for the treatment of Huntington disease.
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that it has received a Complete Response letter for INTUNIV TM (guanfacine) Extended Release from the Food and Drug Administration (FDA). This decision comes following labeling discussions with the FDA that did not result in agreement in time to meet the PDUFA date.
As the world prepares for a probable resurgence of H1N1 in the coming months, University of Pittsburgh researchers are controlling the spread of infectious diseases virtually with a $13.4 million National Institutes of Health (NIH) grant to establish a Center of Excellence in Modeling of Infectious Diseases. The five-year grant, part of the NIH"s Modeling of Infectious Disease Agent Study (MIDAS) program, funds the development and testing of computer simulations that will ultimately enable public health officials and policymakers to evaluate intervention strategies to contain infectious disease outbreaks.
Actually, Failure Is An Option Congress Daily
"A U.S. plan to rely on swine flu vaccines without ingredients to stretch the supply [known as adjuvants] would reduce the number of available shots just when other countries need them most, the British journal Lancet said in an editorial," Bloomberg writes. On July 7, the WHO recommended the use of adjuvants - "mixes of oil and water that trigger a stronger response in the body to antigen, the substance that induces immunity" - to increase the global vaccine supply. Though adjuvants are not approved for flu vaccines in the U.S., HHS" decision to declare the H1N1 flu a public health emergency in April gave the FDA the go-ahead to use "unapproved medical products including adjuvants," according to Bloomberg.
Survivors of the childhood cancer neuroblastoma are eight times more likely to have chronic health conditions, less likely to be married, and more likely to have lower incomes than their siblings, according to a study published online July 31 in the Journal of the National Cancer Institute.
UroToday.com - An unspoken and perhaps forgotten enigma of cancer is its relative drug sensitivity. After all, when treated with cytotoxic agents, a tumor may regress while most normal tissues and organs are either left virtually intact or become eventually healed. Only because a tumor rarely gets into a complete remission, and keeps recurring despite treatment, do we consider cancer generally drug-resistant. Does this dichotomy of drug sensitivity versus resistance allude to a secret about cancer"s complex nature and mysterious origin?
UroToday.com - Empirical medical treatment for idiopathic male factor infertility is a controversial issue. Several medications are used empirically for the treatment of idiopathic male factor infertility, including follicle stimulating hormone (FSH), antiestrogen, L-carnitine, and antioxidants. In this study, we attempted to evaluate the effectiveness of the combination of clomiphene citrate and vitamin E in the management of men with idiopathic infertility.
Data presented today at the 8th European Congress on Menopause
On Friday Congresswoman Lois Capps celebrated the Energy and Commerce Committee"s passage of comprehensive health insurance reform, the America"s Affordable Health Choices Act (H.R. 3200). For the first time the Energy and Commerce Committee has passed a comprehensive health insurance reform bill, marking a historic point in the effort to lower health care costs for families and businesses, improve American"s health and wellness, and provide all Americans with access to quality, affordable health care. The measure passed by a vote of 31 to 28.
ImmunoGen, Inc. (Nasdaq: IMGN), a biopharmaceutical company that develops targeted anticancer therapeutics using its Targeted Antibody Payload (TAP) technology, today announced the presentation of encouraging initial efficacy, safety and tolerability clinical data with its IMGN901 product candidate in the treatment of small-cell lung cancer (SCLC). In two early-stage clinical trials that enrolled patients whose SCLC had recurred following treatment with standard chemotherapies, IMGN901 administration achieved notable tumor shrinkage and/or sustained stable disease. The compound also demonstrated encouraging activity against other CD56-expressing (CD56+) solid tumors. These clinical data are being presented at the 13th World Conference on Lung Cancer taking place in San Francisco, CA, from July 31 to Aug. 4, 2009.
Reports published today in the Annals of Nutrition and Metabolism suggest that many people are confused about the health consequences of fats consumed. Often fat is not considered to be part of a healthy, balanced diet. Also many do not know that there are good, and even essential, fats. As a result, the quality of fats they consume is not in line with recommendations. To help overcome this problem, experts suggest that simple dietary changes be made, such as replacing full fat dairy (e.g. fatty cheeses) and meat products with lean choices, and use of fats and oils of vegetable origin rich in essential fats (sunflower oil, rapeseed oil, soybean oil and products made of these oils such as margarines) rather than of consuming fat of animal origin (lard, butter, etc).
Sedentary behaviors such as TV viewing and "screen time" involving computer use, videos and video games appear to be associated with elevated blood pressure in children, independent of body composition, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
Researchers from the Peninsula Medical School in Exeter have synthesized a new molecule which releases hydrogen sulfide (H2S) = the gas that gives rotten eggs their characteristic smell and which has recently been found to be produced naturally in the body - and discovered that it could in time lead to a range of new, safer and effective anti-inflammatory drugs for human use.
New sequencing and analysis of six strains of Chlamydia will result in improved diagnosis of the sexually transmitted infection. This study provides remarkable insights into a new strain of Chlamydia that was identified in Sweden in 2006 after spreading rapidly across the country by evading most established diagnostic tests.
"[T]he White House team is retooling its message and strategy, hoping a more modest approach will reinvigorate Obama"s signature domestic policy initiative and give him a first-year victory for Democrats to carry into the 2010 midterm elections," the Washington Post reports. An early focus on "fast, broad and bipartisan" reforms has given way to realities including a stiff Republican opposition, lack on consensus in his own party, and falling poll numbers. As a result, the administration and Democratic allies have missed a self-imposed August deadline, turned to harsher critiques of industry players and now appear open to both less-ambitious proposals, and procedural measures that could bypass GOP opposition to achieve a partisan reform bill (Connolly, 8/2).
"Federal health agencies, seeking to hand out stimulus funds to research the effectiveness of various medical treatments, said they will include projects that look in part at the cost of drugs and other treatments. The approach -- which was unveiled in a report to Congress this week by the Agency for Healthcare Research and Quality and the National Institutes of Health, both agencies under the Department of Health and Human Services -- could provide more fodder to conservatives worried that the government might use the results of such studies to limit health care to consumers," the Wall Street Journal reports.
A Wilmington News Journal editorial discussed the potential lifting of the ban on using federal funding for needle exchange programs. The editorial notes recent Congressional action and the restrictions in a House bill that prohibit needle exchanges to operate "within a 1,000 feet of day care centers, schools, parks, playgrounds, pools and youth centers." According to the News Journal, "This rule wipes out much of the flexibility many cities need in their fight to prevent the spread of HIV among intravenous drug users. The nation"s capital, where the rates of HIV and AIDS cases are considered epidemic, would be hit the hardest because no part of the District of Columbia would be eligible for the funding according to AIDS Action." The editorial adds, "Vans patrolling near vulnerable populations - specifically young, impressionable children - are an issue that must be addressed. But well-intentioned limits should not be allowed to hold up the rest of the program," according to the News Journal (8/1).
The House Energy and Commerce Committee on July 31 approved its health care reform bill (HR 3200) by a 31-28 vote that was mostly along party lines, the AP/Seattle Times reports. Among the many amendments considered during the markup, the committee rejected an amendment offered by Reps. Joe Pitts (R-Pa) and Bart Stupak (D-MI) to prohibit government subsidies to any insurance plans that offers abortion coverage, effectively prohibiting abortion coverage for customers eligible for public premium assistance. The amendment was rejected by a 27-31 vote. Another provision approved on July 30 would neither require nor prohibit insurance companies from providing coverage for abortion services.The approved bill includes provisions limiting how much insurers can increase premiums and gives the federal government the power to negotiate with drug companies for lower prices under Medicaid. The provisions were part of an effort by Democrats on the committee to reconcile the demands of liberals and conservatives, the AP/Times reports. The bill also would require insurance companies to sell coverage to anyone seeking it, regardless of pre-existing conditions. The government would provide subsidies to lower-income families to help them afford policies. In addition, the legislation would establish health insurance exchanges offering a variety of insurance plans, where consumers with or without subsidies could purchase health insurance (Espo/Werner, AP/Seattle Times, 8/1).Five of the committee"s Democrats joined all 23 Republicans in opposing the measure, the Washington Post"s "Capitol Briefing" reports. The five Democrats who voted against the bill were Reps. John Barrow (Ga.), Rick Boucher (Va.), Jim Matheson (Utah), Charlie Melancon (La.) and Bart Stupak (Mich.) (Kane, "Capitol Briefing," Washington Post, 7/31).The committee was the last of three House panels to take action on the legislation, although the vote comes several weeks after the White House and Democratic leaders originally wanted, the AP/Times reports. The full House is expected to vote on the bill after policymakers return from their August recess.Although the House"s agenda has moved slower than party leaders had hoped, it still was faster than the action in the Senate, according to the AP/Times (AP/Seattle Times, 8/1). Senate Finance Committee Chair Max Baucus (D-Mont.) on July 30 announced that the panel will not mark up a health care reform bill this week after Republican negotiators urged that the speed of discussion in the Senate be slowed, the Post"s "44" reports. The announcement means that health care reform legislation will not be out of committee in both chambers before the summer recess (Pershing, "44," Washington Post, 7/31).Catholic Bishops Say That House Bill Could Expand Abortion Coverage In related news, the U.S. Conference of Catholic Bishops in a letter to members of the House Energy and Commerce Committee voiced its opposition to the reform bill, arguing that it could be used to require private health insurance plans to cover abortion services, the Post reports. The bill has been opposed by conservative Christian groups for weeks, with the groups arguing that it could be used to expand abortion rights, the Post reports.In the letter, Cardinal Justin Rigali -- chair of the Committee on Pro-Life Activities -- said the bill could increase federal funding for abortion services because some government funding would not be covered by the Hyde Amendment, which currently bans the use of federal Medicaid funds for abortion services. Rigali also said the bill could overturn state laws that restrict access to abortion services, such as parental notification laws. In addition, Rigali said the bill should continue to ensure provider conscience rights to protect Catholic health care workers who refuse to provide abortion services based on their religious or moral beliefs (Washington Post, 8/1).
Rummaging through a biotechnology company"s chemical closet, Yale University researchers found two molecules that will allow scientists to better study how cells move. The study in the journal Nature, published online Aug. 2, describes how two small molecules discovered by Cytokinetics Inc. block the action of a key complex that directs the assembly of actin filaments, which produce the force to help cells move. The target of these inhibitors is the Arp2/3 complex, a cellular component so vital that cells die without it. This dependence has made it challenging to learn exactly which cellular processes depend upon the complex.
Survivors of the childhood cancer neuroblastoma are eight times more likely to have chronic health conditions, less likely to be married, and more likely to have lower incomes than their siblings, according to a study published online July 31 in the Journal of the National Cancer Institute.
Regular yoga practice is associated with mindful eating, and people who eat mindfully are less likely to be obese, according to a study led by researchers at Fred Hutchinson Cancer Research Center.
Researchers at the University of Minnesota and National Institutes of Health have identified a new function for the protein missing in people with the most common and ultimately lethal form of childhood muscular dystrophy.
Brain scientists and cardiac surgeons at Johns Hopkins have evidence from 227 heart bypass surgery patients that long-term memory losses and cognitive problems they experience are due to the underlying coronary artery disease itself and not ill after-effects from having used a heart-lung machine.
BMA Cymru Wales on Monday launched a campaign aimed at improving the working lives of junior doctors in Wales.
A new class of antibody drugs may provide a powerful new tool for the treatment of eye diseases in children, but specialists need to be alert for the possibility of serious side effects, according to an editorial in the August Journal of AAPOS (American Association for Pediatric Ophthalmology and Strabismus), published by Elsevier.
La Jolla Institute for Allergy and Immunology researchers studying an enzyme believed to play a role in allergy onset, instead have discovered its previously unknown role as a tumor suppressor that may be important in myeloproliferative diseases and some types of lymphoma and leukemia. Myeloproliferative diseases are a group of disorders characterized by an overproduction of blood cells by the bone marrow and include chronic myeloid leukemia. Lymphoma and leukemia are cancers of the blood.
Nurses who make home visits to children with asthma can help prevent half of those children from having to receive more serious treatment for their condition, suggests research published ahead of print in the Archives of Disease in Childhood.
Over two-thirds of American families are "blended," which means they are made up of remarried adults and often stepchildren. Although it"s good news that many divorced people remarry, the bad news is that too many of them carry the animosities and negative behavior patterns of their former heartbreaks into their new situation.
The 128,000-member American College of Physicians (ACP) has endorsed the Preserving Patient Access to Primary Care Act of 2009 (H.R. 2350), introduced by Rep. Allyson Schwartz (D-PA). "Primary care is the best medicine for better health and lower costs," ACP noted, "and this is the best medicine for curing the growing crisis in primary care."
BioTrends Research Group, Inc. released TreatmentTrends(R): US Nephrology, a syndicated report analyzing treatment practices, attitudes and perceptions based on online survey results from over 200 US Nephrologists. The survey was fielded in late May and focuses on trends in treatment patterns for renal anemia, secondary hyperparathyroidism and hyperphosphatemia.
Eczema is a chronic skin disorder characterized by dry, itchy, scaly skin and rashes. It is commonly known as "the itch that rashes." (1) While the exact cause of eczema is not known, it appears to result from a complex interaction of factors including personal and family genetics, immune response and environmental factors. (2)
Boston"s health agency on Tuesday is scheduled to launch a safer-sex campaign that reaches out to teenagers through Web sites such as Facebook and YouTube, the Boston Globe reports. The campaign was created in response to rising rates of sexually transmitted infections among young people in the city, according to the Globe. The $100,000 campaign originally was intended to address communicable diseases in general. However, experts noticed the increase in STI cases among teenagers and decided to spend all the funding on the campaign targeting STIs.The increase in chlamydia cases in particular demonstrates the "scope of the challenge," as 1,383 Boston youths between ages 15 and 19 were diagnosed with the STI in 2007, a 70% increase since 1999, the Globe reports. The overall rate of chlamydia in Boston is more than twice the national average, and chlamydia and gonorrhea are more common among adolescents than any other age group in Boston. According to the Globe, a city study released in early 2009 found that 56% of Boston public high school students have had sex, and 24% of the sexually active students said they have had more than six partners.For the campaign, "teenagers will do much of the talking" in a video that offers information on STIs, the Globe reports. The video will air on cable channels that are popular with teenagers, such as MTV, FX and BET. It shows teenagers in a classroom receiving information on safer sex, including details about condoms and STI screening. The video does not discuss sexual abstinence.The campaign also includes advertisements on mass transit and the radio, as well as a team of teenagers that will travel around Boston performing street theater addressing the risks associated with STIs. Through the social networking Web site Facebook, teenagers can post questions anonymously regarding sexual health that will be answered by a disease specialist. Videos related to the campaign also will be posted on YouTube.Margaux Joffe, multimedia coordinator at the Public Health Commission, said teenagers "told us, "We don"t want some 40-year-old woman telling us about sex and STIs."" Joffe added that it "makes sense" because a teenager "may not trust the advice of an adult as much as you would someone in your peer group." Mark Schuster, the chief of general pediatrics at Children"s Hospital Boston who was not involved in the design of the campaign, said that using a "multilevel approach" to address the issue is a "great strategy." He added that young people "can be interested and learn from" a sex education curriculum in school, but "they need it in other settings too."Specialists speculate that the rise in STIs may reflect teenagers" casual attitudes about sex and parents" shifting attention to other children"s health concerns, the Globe reports. Experts also have said that the increase in STIs could reflect increased screening efforts by physicians, who have been "pressed for many years to screen much more carefully kids at younger and younger ages," Stephen Boswell, president of Fenway Health, said. The Globe reports that teenagers do not view HIV/AIDS in the same way previous generations have because of advancements in treatment, so preventing the virus "no longer seems quite as important." Experts are concerned that the spread of other STIs could be a forewarning of a rise in HIV/AIDS cases among teenagers. Anita Barry, a top disease specialist at BPHC, said the gonorrhea and chlamydia cases are "our future HIV cases unless we intervene" (Smith, Boston Globe, 8/4).
Today, the Maricopa County Department of Public Health in cooperation with Phoenix Elementary School District has closed Lowell Elementary School until May 26, 2009 due to a high rate of influenza like illness.
DNA-Prokids (http://www.dna-prokids.org), an international project on human trafficking prevention and fight using genetic identification of victims and their relatives, was officially presented, at the University of Granada (UGR) headquarters, in Spain.
Lifting A Burden Of Worry The Washington Post
Minnesota"s only storefront needle exchange drop-in center, called Access Works!, "fell victim to economic hard times and federal anti-drug policies" and ended its program last week after 13 years, the Minnesota Independent reports. The program "traded used needles for clean ones, conducted HIV and Hepatitis C testing, taught overdose prevention, held support groups and connected users with chemical dependency treatment experts," according to the Independent. Federal funding cannot be used to administer needles for such programs, Lauri Wollner, executive director of the program said. She added, "The federal ban has had a long-term impact. We spend almost $40,000 a year on needles and about $5,000 a year on disposal (of used needles)." Private donations also have been down, she said. While the ban on the use of federal funding for needle exchange is being revisited by Congress, "local needle-exchange activists say it is doubtful that congressional action will be able to save the struggling organization," the article states (Birkey, 8/3).
Officials at an East Texas health care organization, Health Horizons, which provides HIV testing and other services to people in 12 counties, "has seen more East Texans test positive for [HIV] so far this year than it did for all of 2008," the Lufkin Daily News reports. Executive Director Wilbert Brown said, "We"ve had eight people out of more than 800 test positive for HIV in the first seven months of this year. Most of those have been African-American men. Last year we had a total of six out of more than 1,000. I expect us to see two or three more positives before the year is out. The state average for testing positive is one in 100, and we"re getting close to that number." According to the article, "Brown said he attributes the increase to Health Horizon"s aggressive outreach program targeting high-risk groups and to people realizing the importance of getting tested." The Daily News article also profiles a client of Health Horizons (Cooley, 8/2)
The Shreveport Times profiled the 20-year-old Shreveport, La.-based Philadelphia Center, an agency that provides HIV/AIDS services to "an average of nearly 600 people each year in northwest Louisiana" and provides "about 1,400 free HIV tests each year." The organization also has a residential program called the Mercy Center, "a haven for homeless people with HIV or those fighting addiction and other challenges," according to the Times. The center in large part is supported by an annual auction from which proceeds "help the agency operate support groups, coordinate medical, dental and housing services for clients, provide food and medicine to people and offer free, on-the-spot HIV testing," the article states. The center recently opened a satellite office in a nearby town in response to an increase in HIV infections in the area (Brumble 8/2).
New experiments by scientists at the University of Oxford revealed that
Rates of infant death remain high in parts of England, largely among deprived communities and ethnic minorities, finds a study published on bmj.com today.
The active ingredient in many insect repellents, deet, has been found to be toxic to the central nervous system. Researchers writing in the open access journal BMC Biology say that more investigations are urgently needed to confirm or dismiss any potential neurotoxicity to humans, especially when deet-based repellents are used in combination with other neurotoxic insecticides.
On average, not-for-profit nursing homes deliver higher quality care than do for-profit nursing homes, according to a study published on bmj.com today.
Elevated cholesterol levels in midlife - even levels considered only borderline elevated - significantly increase the risk of Alzheimer"s disease and vascular dementia later in life, according to a new study by researchers at Kaiser Permanente"s Division of Research and the University of Kuopio in Finland. The study appears in the journal Dementia & Geriatric Cognitive Disorders.
If you are 50 or older and you break your hip, you have a one in four chance of dying within five years. Break your back, and you have a one in six chance of dying that soon, says a McMaster University study.
A recent study of more than 2,000 identical twins found that medical problems early in life, rather than the neurotoxic effects of anesthesia, are likely linked to an individual"s risk for developing learning disabilities. The study"s findings, reported in the journal Twin Research and Human Genetics, contradict research published earlier this year, which concluded that receiving anesthesia younger than age four is associated with subsequent learning problems.
A recent study by doctors at the University of Washington explained that patients who are significantly underweight or very severely obese prior to liver transplantation are at increased risk of death following transplantation surgery. These findings, from the largest known observation of liver transplantation at the extremes of BMI, are published in the August issue of Liver Transplantation, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases.
Emergency physicians should trust their judgment when evaluating patients who report with chest pain symptoms, said a group of researchers led by Abhinav Chandra, M.D., at Duke University Medical Center.
The amount of money PCTs (primary care trusts) are spending on management consultants has risen enormously, according to Pulse. In comparison to two years ago, the amount PCTs spend during the last financial year on external consultancy fees has risen threefold, according to figures compiled from 62 trusts.
In many types of cancer, parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This kind of methyl labeling ranges among the epigenetic changes that do not change the sequence of DNA building blocks. Such labels are found particularly often in genes which act as important inhibitors of pathogenic cell growth.
Although lead content in paint has been restricted in the United States since 1978, University of Cincinnati (UC) environmental health researchers say in major countries from three continents there is still widespread failure to acknowledge its danger and companies continue to sell consumer paints that contain dangerous levels of lead.
Consumers should be warned about the dangers of eating untreated bitter lupin beans after two people who consumed products containing the beans became ill with anticholinergic syndrome, according to an article in the Medical Journal of Australia.
Just ten hours of the right brain fitness exercises can have a significant and long lasting impact on healthcare costs and outcomes, according to a study recently published in BMC Health Services Research, a leading peer-reviewed health services journal.
Do you intend on getting a healthy tan this summer? You may want to rethink your plans. Tan skin is the body"s reaction to sun damage, along with freckles, wrinkles and brown spots. So unless your tan comes from a bottle, it"s probably not healthy.
A gut hormone first described in 1928 plays an unanticipated and important role in the remote control of blood sugar production in the liver, according to a report in the August 6th Cell Metabolism, a Cell Press publication. What"s more, the researchers show that rats fed a high-fat diet for a few days become resistant to the glucose-lowering hormone known as cholecystokinin (CCK).
HIV and sexual health charity Terrence Higgins Trust (THT) is joining forces with other local HIV organisations to remind visitors to Birmingham Pride (23 - 24 May) not to put their sexual health at risk by getting carried away with the party mood.
Advocates on both sides of the abortion-rights debate are "preparing for a renewed battle" over insurance coverage of abortion services in health care reform efforts, the AP/Atlanta Journal-Constitution reports. Abortion-rights opponents say that current restrictions on federal funding for abortion services should carry over to any insurance sold under new health insurance exchanges proposed under reform legislation. However, abortion-rights supporters say that carrying over the restrictions would deny abortion coverage to millions of women who currently have it through employer-sponsored coverage and are likely to join the exchanges.A variation in how the questions were asked yielded different results but significant proportions of private plans were found to cover abortion services. A Guttmacher Institute study found that 87% of typical employer-sponsored health plans covered abortion services in 2002, and a 2003 Kaiser Family Foundation study found that 46% of workers covered by employer-sponsored plans had coverage for abortion services.A Congressionally imposed provision of law known as the Hyde Amendment currently prevents the use of federal Medicaid funds for abortion services except in cases of rape, incest or life endangerment. States that choose to cover abortion services for low-income women through Medicaid must use their own funding to do so. Other Congressionally imposed restrictions prohibit abortion coverage for federal employees, women in the military and other women who rely on the federal government for their health care coverage. An overhaul of the health care system would "create a stream of federal funding not covered by the restrictions," including federal subsidies to offset the cost of health insurance for low- and middle-income people purchasing public or private health insurance though an exchange, the AP/Journal-Constitution reports.Congressional Proposals The plan passed by the Senate Health, Education, Labor and Pensions Committee is "still largely silent" on the issue of coverage for abortion services, the AP/Journal-Constitution reports. Both the House and Senate bills leave the decision on whether the public plan would include abortion coverage to the HHS secretary.In the House Energy and Commerce Committee, members approved an amendment that would allow the public plan to cover abortion services through the use of beneficiary premiums but not federal funds. In addition, the amendment says that private plans in the insurance exchanges could choose whether to cover abortion services, but no federal subsidies could be used to pay for the procedure. The amendment -- proposed by Rep. Lois Capps (D-Calif.), who supports abortion rights -- also would allow plans that do not cover abortions under any circumstances to be offered through insurance exchanges. Capps said that her amendment aims to appease both sides of the abortion-rights debate, adding, "Our country allows for both sides, and our health plan should reflect that as well."Comments Abortion-rights opponents say that they cannot accept a public insurance plan that would cover abortion services and that private plans in insurance exchanges should offer coverage for abortion services as a separate option, the AP/Journal-Constitution reports. Richard Doerflinger, associate director of antiabortion activities for the U.S. Conference of Catholic Bishops, said the group "want[s] to see people who have no health insurance get it," but coverage for abortion is "a sticking point." He said that there can be a "result where nobody has to pay for other people"s abortions," adding, "We don"t want health care reform to be the vehicle for mandating abortion."However, abortion-rights supporters argue that prohibiting coverage for abortion services would deny health care to women who have abortion services coverage through their private plans. Heidi Hartmann, president of the Institute for Women"s Policy Research, said that applying current restrictions for low-income women and federal employees to a program meant for the middle cla
Massachusetts officials are proud of their low rate of uninsured people, but the state also hosts the highest health care costs in the country, a problem that jeopardizes their achievement in expanding coverage, NPR"s Morning Edition reports. A commission charged with overseeing the insurance plan for 310,000 government workers recently voted - unanimously - that doing away with the current, fee-for-service model for paying doctors was the first step to controlling those costs. "Massachusetts policymakers want to replace fee-for-service with "global payment" - paying groups of health providers a flat yearly fee for each patient they cover," NPR reports (Knox, 8/5).
The Miami Herald reports: "Fueled by massive fraud, home healthcare providers in Miami-Dade County are raking in more Medicare money than their colleagues in the rest of the country combined -- thanks to bogus billings for patients with diabetes, authorities say. Now, Medicare is taking tough steps to stop agencies from filing hundreds of millions of dollars a year in false claims." A federal agency is proposing "a nationwide cap that would reduce Medicare reimbursements to any agency treating homebound patients with diabetes or other chronic ailments. The proposed limit: 10 percent of the bill. Though national in scope, Medicare"s plan is really aimed at shutting down hundreds of home healthcare agencies in Miami-Dade suspected of submitting phony claims for twice-daily insulin injections by a visiting nurse, officials said."
The English word "health" comes from the Old English word hale, meaning "wholeness, a being whole, sound or well,". Hale comes from the Proto-Indo-European root kailo, meaning "whole, uninjured, of good omen". Kailo comes from the Proto-Germanic root khalbas, meaning "something divided". Medilexicon"s medical dictionary has three definitions for health, the first being "The state of the organism when it functions optimally without evidence of disease or abnormality" (click here to read the other two).
The fifth annual report card from the Washington, D.C.,-based Appleseed Center for Law and Justice examining the district"s response to HIV gives the city "high marks for rapid testing, interagency coordination, surveillance and fighting the disease in the D.C. Jail," but finds that the city falls short in other areas, the Washington Examiner reports (Neibauer, 8/5). "The government also received above-average grades for leadership, managing grants to groups that help people with the illness, and monitoring the effectiveness of those programs," the Washington Post reports. However, "While Mayor Fenty and his administration deserve recognition for the continued support of ò€¦ numerous [HIV/AIDS Administration] initiatives, his public appearances and statements about the epidemic have fallen short of his enthusiasm for action inside the government," the report said. The report added that the district could do more to address HIV and recommended that HAA assess whether the improvements they have made are reducing the spread of the virus, according to the Post (Fears, 8/5).
Covidien (NYSE: COV), a leading global healthcare products company and recognized innovator in mechanical ventilation and respiratory care devices, announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its Leak Compensation software feature for the Puritan Bennett 840™ ventilator system. This option provides continuous levels of mechanical ventilation to patients requiring respiratory support, regardless of the level of gas leakage that might occur in the circuit or past a patient interface device in the clinical setting.
It is important to understand what biological mechanisms contribute to an individual"s capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters. Dr. Charles A. Morgan III and his colleagues from Yale University and the VA National Center for PTSD have worked closely with collaborators at the Special Forces Underwater Warfare Operations Center to study special operations soldiers enrolled in the military Combat Diver Qualification Course (CDQC).
As President Obama and Congress weigh changes in the nation"s health care system they must avoid creating a system where physicians are financially motivated to pressure patients into mandated treatments that conflict with their values and needs, two Beth Israel Deaconess Medical Center physicians warn.
BSD Medical Corporation (NASDAQ:BSDM) announced that the U.S. Food and Drug Administration (FDA) has granted Humanitarian Use Device (HUD) designation for the company"s BSD-2000 Hyperthermia System for use in conjunction with radiation therapy for the treatment of cervical carcinoma patients who are ineligible for chemotherapy. This is the first of the two steps required to obtain Humanitarian Device Exemption (HDE) marketing approval, which requires BSD Medical to demonstrate the device"s safety and probable benefit in treating a disease or condition that affects fewer than 4,000 individuals in the United States per year. Now that FDA has granted the Humanitarian Use Designation for the BSD-2000, which confirms that the intended use population is fewer than 4,000 patients per year, BSD can file an HDE submission with the FDA. FDA has 75 days from the date of receipt of the HDE submission to grant or deny an HDE application. This period includes a 30-day filing period during which FDA determines whether the HDE application is sufficiently complete to permit substantive review. During this review, FDA may refine the indications for use which received HUD designation to finalize the indications for use for which HDE approval will be granted. This decision will be based on the data that are available to support the device"s HDE application. The company believes that the data previously submitted to FDA and reviewed by the agency in the company"s pending PMA application can be used to support the HDE approval, and that this previous review may expedite marketing approval for the BSD-2000.
People living with HIV will benefit from a new test developed by Victoria, Australia scientists that offers a simpler and cheaper way of monitoring the disease in sufferers, Victorian Innovation Minister Gavin Jennings said today.
The word "endocarditis" comes from the word "endocardium". The endocardium is the innermost tunic of the heart, including the endothelium and subendothelial connective tissue; in the atrial wall, smooth muscle and numerous elastic fibers also occur.
Otsuka Pharmaceutical Co., Ltd. (OPC) and Otsuka Pharmaceutical Development and Commercialization, Inc. (OPDC) announced that the U.S. Food and Drug Administration (FDA) has approved SAMSCA(TM) (tolvaptan) as the only oral selective vasopressin antagonist for the treatment of patients with clinically significant hypervolemic and euvolemic hyponatremia (serum sodium less than 125 mEq/L, or less marked hyponatremia that is symptomatic and has resisted correction with fluid restriction) including patients with heart failure, cirrhosis, and the syndrome of inappropriate anti-diuretic hormone (SIADH). Patients requiring urgent treatment to raise serum sodium to prevent or to treat serious neurological deficits should not be treated with SAMSCA. Additionally, it has not been established that raising serum sodium with SAMSCA provides a symptomatic benefit to patients. SAMSCA, an oral vasopressin V2-receptor antagonist, will be commercialized in the United States by Otsuka America Pharmaceutical, Inc. (OAPI).