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American Medical Association Commits To Help Slow Increases In Health Spending
"The need for health reform that provides coverage and high quality, affordable health care for all Americans is clear. Rising health-care costs strain individual, business and government budgets, and projected increases in health spending are not sustainable. The AMA is committed to action to help achieve greater value from our nation"s health-care spending. We want to help bend the spending curve and move forward on health reform.
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FOCUS On FOCIS: Combined Chemo-Immunotherapy For The Treatment Of Hormone-Refractory Metastatic Prostate Cancer
UroToday.com - The long-term goal of the Tumor Immunology and Immunotherapy group at The Institute of Immunology, Charles University, 2nd Medical School is the development of dendritic cell-based cancer vaccine. Administration of this vaccine will induce the tumor cell-specific induce response, complement current treatment modalities, and contribute to an improved prognosis of patients with cancer.
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Kansas Becomes Central Battleground In Abortion-Rights Debate
Kansas has become "perhaps the fiercest battleground" in the abortion-rights debate with mass protests, prosecutions, lawsuits and the recent murder of abortion provider George Tiller, the AP/Washington Post reports. Kansas State University political scientist Joe Aistrup said, "There"s a very prominent vein in Kansas politics that tends toward moral righteousness." He said that this contributes to that unending debate and has produced extremists on both sides of the issue in the state.Peter Brownlie, CEO of Planned Parenthood of Kansas and Mid-Missouri, said that the majority of those who maintain the intense debate on abortion rights are political leaders. "There is a very clear and growing gap between the general public and the political leaders who are committed to this being such a constant and volatile issue," he said. Brownlie added that on issues relating to abortion, sex education and family planning, "Kansans" views are not markedly different from most Americans, but there are political forces at work, some of them well beyond the state borders."The Post reports that Kansas is different than most states where either supporters or foes of abortion rights dominate. According to the AP/Post, Kansas often sways between having key lawmakers who support abortion rights and those who oppose them. For example, a Republican-dominated Legislature over the past six years passed several bills to restrict abortion access, but much of the legislation was vetoed by former Gov. Kathleen Sebelius (D). The result has triggered frustration in groups opposing abortion rights, and they continue to feed widespread opposition to abortion in the state, the AP/Post reports.According to Burdett Loomis, a University of Kansas political science professor, there even is a split among Kansas Republicans in regard to abortion rights, as some Republicans in the state are evangelical Christians who oppose abortion rights, while others are moderates who support such rights. He said the split "might pop out in gun laws, home schooling, evolution, but it starts and stops with abortion" (Crary/Hanna, AP/Washington Post, 6/3).Wall Street Journal Examines Abortions Later in PregnancyIn related news, the Wall Street Journal on Thursday examined how Tiller"s clinic in Kansas became a battleground in the abortion-rights debate particularly because some of his patients were in the second and third trimesters of pregnancy. According to the Journal, even though the subject of abortion later in pregnancy is the of "a deep cultural divide," both sides agree that it is "anguishing." Fewer than 1% of all abortions in the U.S. are performed in the second or third trimesters, and most states prohibit abortions late in pregnancy but include exceptions for the woman"s life and health.The Journal reports that abortion procedures performed later in pregnancy often carry increased health risks, are more expensive and are emotional. The Guttmacher Institute reports that 8.9 maternal deaths occur during every 100,000 abortions performed later in pregnancy, compared with 7.1 deaths per 100,000 births. The article also profiled women who chose to undergo abortions later in pregnancy at Tiller"s clinic, as well as arguments from abortion-rights opponents (Simon, Wall Street Journal, 6/4).

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Health Overhaul Issues Fill The Sunday Talk Shows

Health experts and politicians filled Sunday talk shows as Obama administration officials push for reform.

Larry King Talks About His Diabetes For The First Time

Broadcasting legend Larry King turns the tables to talk about himself in his new autobiography, "My Remarkable Journey," but doesn"t mention the chronic disease he"s lived with for nearly fifteen years: type 2 diabetes. In an interview with Diabetes Forecast, the consumer magazine of the American Diabetes Association, King discusses his diabetes publicly for the first time, and explains how his health, lifestyle, and personality influence one another.

New Research Evaluates The Impact Of Working Memory Training And Stimulant Medication On Kids With ADHD

A study to be published in the August 2009 edition of Applied Cognitive Psychology sheds new light on how Cogmed Working Memory Training and stimulant medication address working memory impairments in children with ADHD. Working memory, acknowledged as one of the core deficits in ADHD, represents the brain"s ability to hold and process critical information related to the present moment. This study represents the latest findings from a team of independent UK researchers whose ongoing work examines the impact of Cogmed"s software-based training program on individuals with disorders of memory and attention.

California Budget Could Force Seniors To Nursing Homes, Drive Up Costs

NPR reports that California"s $26.3 billion budget deficit is marginalizing seniors who rely on California state-provided health care and service to help them manage their lives.

Group Files Petition Over Enforcement Of Regulations In Adult Film Industry To Prevent Sexually Transmitted Diseases

The AIDS Healthcare Foundation last week filed a petition in Los Angeles County Superior Court asking "the court to order the Los Angeles County Department of Public Health to enforce regulations that require condom use in adult-film production or take other reasonable steps to stem the spread of disease," the Los Angeles Times reports (Yoshino, 7/17). In the petition, "the group claims that in the month since an actress tested positive for HIV, the county Department of Public Health has done little to address what it considers to be a serious health threat" (AP/San Jose Mercury News, 7/16). In a statement released last week, the department, said, "The county continues to strongly support state legislation and the regulatory role of the [California Division of Occupational Safety and Health] as the most appropriate means to regulate the practices in the adult-film industry that expose performers to unnecessary and preventable occupational risks of acquiring and transmitting these diseases," adding, "The department does not believe that litigation is the best means to deal with this issue" (Yoshino, 7/17).

Diet Restriction Can Lead To Unwanted Changes In Immunity

Why do animals lose their appetites when sick? Should this inform our

Food Manufacturers Must Step Up To The Plate And Reduce Salt Levels, Says Heart Charity

In response to Food Standards Agency"s new guidelines on voluntary salt reduction targets, Alex Callaghan, Policy Officer at the British Heart Foundation (BHF), said:

First Genetic Evidence For Why Placebos Work Presented By UCLA Scientists

Placebos are a sham - usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.

No Race Disparities In Risk Of AIDS And Death In HIV Patients In Kaiser Permanente System

Kaiser Permanente researchers found no disparities by race or ethnicity in risk of AIDS and death among HIV-infected patients in a setting of similar access to care. This is despite lower Anti-Retroviral Therapy adherence among Hispanics and African-Americans compared to whites. Researchers also saw a trend toward better outcomes for Hispanics.

New Collaboration To Conduct A Clinical Trial Of TB Vaccine Candidate In People Living With HIV

The Aeras Global TB Vaccine Foundation (Aeras) has announced a new collaboration with The Aurum Institute on the first study to test the AERAS-402/Crucell Ad35 tuberculosis (TB) vaccine candidate for safety in people living with the human immunodeficiency virus (HIV). Aurum will conduct this trial in people living with HIV at its clinical trial site near Johannesburg, South Africa. The Medicines Control Council of South Africa and two Independent Ethics Committees in South Africa have given approval to test the vaccine in South Africa. AERAS-402/Crucell Ad35 has been previously tested for safety in healthy adults in the United States and HIV-negative adults and infants in South Africa.

John Kufuor Leads Effort To Fight Global Hunger Among Schoolchildren

The former Ghanaian president, John Kofi Agyekum Kufuor, has

FDA Accepts For Review Spectrum\'s Response On ZEVALIN As A Class 1 Submission, And Establishes September 7, 2009 As Decision Date

Spectrum Pharmaceuticals, Inc. (NasdaqGM: SPPI), a commercial stage biotechnology company with a focus on oncology, announced that the U.S. Food and Drug Administration (FDA) has accepted for filing and review the resubmission to the Company"s supplement to the biologics license application for ZEVALIN (ibritumomab tiuxetan) in the first line consolidation setting on July 8, 2009. The FDA considers the review as a Class 1 submission to their complete response letter of July 2, 2009. Therefore, the user fee goal date is September 7, 2009.

Critical Outcome Technologies Inc. Announces The Launch Of A Drug Discovery Program For Alzheimer\'s Disease

Critical Outcome Technologies Inc. (COTI)(TSX VENTURE:COT), announced that the Company has undertaken the discovery and optimization of novel lead compounds for the treatment of Alzheimer"s Disease (AD). "Based on partnering interest expressed by multiple global pharmaceutical organizations we have decided to establish a drug discovery program to help combat this devastating disease", said Mr. Michael Cloutier, Chief Executive Officer of COTI.

Poniard Pharmaceuticals Announces Positive Cardiac Safety Data From Picoplatin Phase 1 Trial Supporting NDA Filing

Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on innovative oncology therapies, announced results from a Phase 1 cardiac safety study of picoplatin, a new generation platinum-based chemotherapy agent and the Company"s lead product candidate. The Company worked collaboratively with the U.S. Food and Drug Administration (FDA) to design this study, which is required for new chemical entities.

Landmark Kidney Cancer Data Published By The Journal Of Clinical Oncology

Results from a landmark study published by the Journal

University Of Maryland Dental School Helps Doctors, Nurses Halt Infant Tooth Decay

Across the state of Maryland, there are now doctors and nurses, freshly trained in pediatric dental health care, who can help stem an alarming number of 3-year-old children who arrive for their first dentist visit with teeth "just melting away."

Troubled Mental Health Trust Symptomatic Of Failings Nationwide, UK

A damning report from the Care Quality Commission has found multiple failings in inpatient care for patients at West London Mental Health Trust, ranging from sub-standard buildings, overcrowding, lack of staff and insufficient staff training, to failure to implement changes that could help prevent suicides on wards. In some areas, there were long delays in considering changes to help reduce suicide risk, and on one inpatient unit, bed occupancy was regularly running at over 110 per cent, resulting in patients sleeping on sofas due to lack of beds.

National Organization for Women Establishes Kansas Abortion-Rights PAC To Fill Void After Death Of Abortion Provider Tiller

The Kansas chapter of the National Organization for Women has formed its own political action committee to replace ProKanDo, a PAC founded in 2002 by abortion provider George Tiller that was closed after his murder in May, the AP/Hays Daily News reports. ProKanDo spent more than $1 million over the last four years to advocate for abortion rights, assist candidates who support abortion rights and oppose antiabortion-rights candidates. The organization had more than 6,400 contributors but received between one-third and one-half of its annual funding from Tiller, according to former Director Julie Burkhart.NOW has scheduled a conference in Wichita on July 25 to discuss legislative strategy and Kansas elections. Marla Patrick, coordinator of NOW"s Kansas chapter,÷ said that although the new PAC will not have the same financial support from Tiller that ProKanDo received, his death has invigorated grassroots support. She added, "I think that can be every bit as effective, if not more so, especially in light of all the recent events" (Hegeman, AP/Hays Daily News, 7/18).

Hampton Court Allergy Screening A Success, UK

The National Pharmacy Association and Allergy UK provided free allergy screening to the public at Hampton Court Palace Flower Show from 7-12 July. Over 7,000 members of the public picked up information on community pharmacy allergy screening or asked for advice and 75 allergy screenings were carried out.

Patients And Health Care Providers Seek Improved Quality As Report Shows Extensive Errors

The Washington Post reports on efforts by hospitals to tally their avoidable mistakes and describes "hundreds of incidents of death or serious medical harm disclosed in the past year by hospitals in the Washington region, preventable errors that until recently have not required public reporting. Under laws that took effect last year in Virginia and a few years earlier in the District and Maryland, hospitals must report to health regulators many serious injuries that patients suffer in the course of treatment. The laws are different in each jurisdiction. For example, Virginia"s public records identify the hospitals by name, while Maryland"s and the District"s do not. But they all allow the public to glimpse the breadth of mistakes that health experts dub "never events" (because they should never happen): sponges left inside patients after surgery, operations on the wrong limb, medication errors, falls that lead to needless deaths (as well as other events). At least 20 states require hospitals to report every incidence of hospital-acquired infection. Patients, insurers and regulators are beginning to use this information to prod health-care providers to ensure that such events really never happen."

More Progress Still To Be Made On Mental Health

Commenting on the final biennial report from the Mental Health Act Commission released by the Care Quality Commission, Mental Health Network director Steve Shrubb said:

Leadership The Key To Learning From Tragedies

Commenting on the Care Quality Commission"s report into the West London Mental Health Trust, NHS Confederation Chief Executive Steve Barnett said:

Foundation Trusts Welcome Inquiry Into Mid Staffordshire

The Department of Health announced there would be an independent investigation into Mid Staffordshire NHS Foundation Trust and has proposed changes to legislation governing Foundation Trusts.

National Public Reporting Of Health-Care-asociated Infections Supported By Experts

Five organizations representing the nation"s experts in infectious diseases medicine, infection prevention in healthcare settings, and public health and disease prevention announced their support for a provision requiring national reporting of healthcare-associated infection (HAI) rates, which is contained within the healthcare reform bill introduced by leaders of the U.S. House of Representatives.

ACCP Position Paper On Genetic Tests Advertised Directly To The Consumer

Genetic testing services have recently begun to be advertised directly to the patient, and the results of the consumers" response can affect public health, as well as the future adoption of pharmacogenetic/genomic testing, according to a position paper from the American College of Clinical Pharmacology (ACCP) to be published in the August 2009 issue of the Journal of Clinical Pharmacology. The journal is published on behalf of the ACCP by SAGE.

A Single Atom Makes A Big Difference To Purer Water

By substituting a single atom in a molecule widely used to purify water, researchers at Sandia National Laboratories have created a far more effective decontaminant with a shelf life superior to products currently on the market.

Reducing P38MAPK Levels Delays Aging Of Multiple Tissues In Lab Mice

In the new issue of the Developmental Cell journal, a team of scientists at Singapore"s Agency for Science, Technology and Research (A*STAR) and the University of North Carolina School of Medicine at Chapel Hill, report research findings about the molecular mechanisms behind the aging process, which has up till now been poorly understood, that offer the possibility that a novel, pharmacological approach could be developed to combat age-related disorders.

European Travellers Continue To Put Their Health At Risk

European travellers are still putting their health at risk says the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), with one third experiencing travel-related illness when visiting abroad. On a typical two-week trip, travellers lose an average of three days due to illness - almost 20 percent of them remain ill after their return home, and another 10 percent need medical care.

Optical Chip Detects Blood Molecules

A portable "lab on a chip" that can identify target molecules in blood samples has been created by European researchers. It is being used to measure fertility hormones and detect the genes associated with certain types of cancer.

Biomarkers May Help Predict Risk Of Alzheimer Disease In Patients With Mild Cognitive Impairment

Several cerebrospinal fluid (CSF) biomarkers showed good accuracy in identifying patients with mild cognitive impairment who progressed to Alzheimer disease, according to a study in the July 22/29 issue of JAMA.

Adopting Low-Risk Dietary And Lifestyle Factors Related To Lower Incidence Of High Blood Pressure

Adherence to modifiable lifestyle and dietary factors including maintaining normal weight, daily vigorous exercise, eating a diet high in fruits, vegetables, low-fat dairy products and low in sodium and taking a folic acid supplement was associated with a significantly lower incidence of self-reported hypertension among women, according to a study in the July 22/29 issue of JAMA.

UC Berkeley Researchers Bring Fluorescent Imaging To Mobile Phones For Low-cost Screening In The Field

Researchers at the University of California, Berkeley, are

National Cancer Institute Research Identifies Unique Mechanism Of Brostallicin\'s Anti-Tumor Effectiveness

Cell Therapeutics (CTI) (Nasdaq and MTA: CTIC) announced that researchers from the Laboratory of Molecular Pharmacology at the National Cancer Institute presented new preclinical research identifying unique anti-tumor mechanisms of brostallicin that sets this agent apart from other currently used chemotherapy agents. CTI acquired worldwide rights to brostallicin when it acquired privately-held Systems Medicine LLC in 2007. Published in the journal Molecular Cancer Therapy (Mol Cancer Ther 2009;8(7) July 2009; 1985-94), the researchers utilized preclinical studies to provide clues into tumor susceptibility mechanisms for brostallicin, a synthetic DNA minor grove binder, and to identify differences between brostallicin and trabectedin (Yondelis(R); ET-743), which is a natural marine product approved in Europe. Unlike other chemotherapy agents, including trabectedin, the NCI research indicates that the tumor cell DNA damaging effects of brostallicin are enhanced by high tumor glutathione levels, a hallmark of drug-resistant tumors. Brostallicin was shown to affect DNA in both dividing and quiescent cells. Its actions can be followed by induction of a specific DNA binding protein foci that can be detected in circulating blood cells. Importantly, brostallicin was active in a trabectedin-resistant cell line.

Survey: 40 Percent Of Senior Citizens Not Taking Prescribed Medicines Due To Budget Concerns

A new survey, released today by The Senior Citizens League (TSCL), found that senior citizens are being forced to make drastic cuts to their medical and food budgets due to the recession.

US To Start Human Trials Of H1N1 Swine Flu Vaccine In August

The United States will start human trials of an experimental vaccine for preventing the 2009 H1N1 influenza virus in August; the first

Obama Says Lawmakers Should Not Become Sidetracked By Abortion Debate In Health Reform

In an interview with CBS" "Evening News" on Tuesday, President Obama said that lawmakers should "not get distracted by the abortion debate" as they weigh health reform legislation. When asked by "Evening News" anchor Katie Couric if he would "favor a government option that would cover abortions," Obama replied that what he thinks is "important, at this stage, is not trying to micro-manage what benefits are covered." He added that his "main focus is making sure that people have the options of high-quality care at the lowest possible price." Obama also said, "As you know, I"m pro-choice. But I think we also have the tradition of, in this town, historically, of not financing abortions as part of government-funded health care." He continued that "[r]ather than wade into that issue at this point, I think it"s appropriate for us to figure out how to just deliver on the cost savings, and not get distracted by the abortion debate at this station" (Couric, "Evening News," CBS, 7/21).

Health Care Overhaul Could Include Changes To Doctor Payments

The Wall Street Journal reports that "Democratic centrists said they won a tentative commitment from the White House to back a proposal to curb the growth of Medicare costs. ... One proposal pushed both by President Barack Obama and some centrists is to give the executive branch the authority to implement cuts to Medicare spending that would be recommended by independent experts. Congress could stop the cuts, but only if it acted swiftly. Fiscal conservatives say that under the current system, which gives Congress more power, lawmakers shy away from politically tough votes to restrain Medicare costs."

Insurers \'Spinning\' Some Data To Shape Reform

Insurers sometimes cherry-pick facts to make their case against certain aspects of reform efforts, including a public plan, The Washington Post reports.

ANA Responds To Recent Negative Portrayals Of TV Nurses Who Violate Nursing Code Of Ethics

At a time when the entertainment industry is perpetuating inaccurate portrayals of nursing in the new television shows "Nurse Jackie" and "HawthoRNe," ANA"s ethics books are especially relevant to all registered nurses (RNs). The fictional nurses are shown violating the nursing Code of Ethics by participating in activities ranging from on-the-job drug use to inappropriate nurse/patient contact in these shows. The very heart of nursing is mischaracterized as nurses are portrayed engaging in irresponsible and often criminal acts for entertainment purposes. ANA sets the ethical standards for nurses in the U.S. and internationally with its highly respected Code of Ethics for Nurses with Interpretive Statements, and is deeply concerned about the lasting impact these negative portrayals may have on the nursing profession.

Some Health Groups Increase Lobbying Spending, But Only A Slight Rise Overall

"Drug makers, advocacy groups, biotechnology firms and insurance companies have ratcheted up efforts to offer their two cents - and in most cases much, much more - in influencing the health care legislation now working its way through Congress," The New York Times reports. "Many familiar health groups in recent months have increased lobbying spending by more than $1 million, according to second-quarter lobbying records filed on Monday with the Senate Office of Public Records." Those groups include AARP and The Blue Cross and Blue Shield Association. Drug makers GlaxoSmithKline and Novartis, along with insurance company Allstate and biotechnology firm Amgen have also invested significantly more in lobbying activities."

MitraClip(R) Therapy Data Demonstrate Clinical Benefit In High-Risk Patients With Mitral Regurgitation

Results show percutaneous mitral repair using the MitraClip(R) system in symptomatic high-risk surgical patients with either functional mitral regurgitation (FMR) or degenerative mitral regurgitation (DMR) improves patient clinical status. The results from the 78 patient EVEREST II High Risk Registry demonstrated improvement in left ventricular function and reduced hospitalization for congestive heart failure for both MR groups at twelve months. Additionally, a reduction in mortality compared to the predicted mortality risk of surgery was reported for the registry. The results of the High-Risk Registry were presented at the third annual meeting of EuroPCR, the official congress of the European Association of Percutaneous Cardiovascular Interventions (EAPCI).

General Practices Need More Nurses, Australia

Boosting the number of practice nurses who work with GPs would help improve patient access to care, the AMA said today.

Are Blood Transfusions Bad For Your Health?

The August issue of the journal Anesthesiology, contains a study on potential long-term adverse effects resulting from blood transfusion and reveals that moderate amounts of transfused blood in patients in patients undergoing cardiac surgery did not lead to long-term health problems or increased death rates for the majority of recipients.

SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(R) Stent System More Cost Effective Than Bypass Surgery In Patients With Complex Artery Disease

Boston Scientific Corporation (NYSE: BSX) announced results from an analysis of economic and quality of life outcomes, based on one-year data from its landmark SYNTAX trial. The results found that percutaneous coronary intervention (PCI) using the TAXUS(R) Express2(R) Paclitaxel-Eluting Coronary Stent System was consistently associated with fewer patient hospital days during the first year after treatment compared to coronary artery bypass graft (CABG) surgery. Total medical costs at one year were also lower with PCI. Analysis of the data was presented by Ben van Hout, Ph.D., of the University of Utrecht, The Netherlands, at the annual EuroPCR Scientific Program in Barcelona.

Study Provides Documentation That Tumor "Stem-like Cells" Exist In Benign Tumors

Cancer stem-like cells have been implicated in the genesis of a variety of malignant cancers. Research scientists at Cedars-Sinai Medical Center"s Maxine Dunitz Neurosurgical Institute have isolated stem-like cells in benign (pituitary) tumors and used these "mother" cells to generate new tumors in laboratory mice. Targeting the cells of origin is seen as a possible strategy in the fight against malignant and benign tumors.

Chicago Students To Get Lessons On Diagnostic Testing From The "Unsung Heroes" Of The Clinical Lab Profession

Chicago high school students interested in science and health care will get a chance to learn about diagnostic tests and the laboratory professionals who perform them during the American Association for Clinical Chemistry"s 2009 Clinical Lab Expo on July 21 and 22.

Consumers May Not Get A Clear Picture Of The Process When Food Gets Inspected And Recalled

Consumers usually find out pretty quickly if the meat they"re planning to throw on the grill has been recalled.

Personalizing Medical Care: An Inner \'Fingerprint\'

Fingerprints move over. Scientists are reporting evidence that people have another defining trait that may distinguish each of the 6.7 billion humans on Earth from one another almost as surely as the arches, loops, and whorls on their fingertips. In a study scheduled for the Aug. 7 issue of ACS" monthly publication the Journal of Proteome Research, they report evidence from studies in humans for the existence of unique patterns in metabolism.

Integrative Medicine Critical To Healthcare Reform - American College for Advancement in Medicine

The American College for Advancement in Medicine (ACAM) has released its position regarding HB 3200, the health care reform bill proposed by the Obama administration. While ACAM believes healthcare reform is vital and necessary for America, it is our position that integrative medicine principles be included to yield the desired result of creating a more efficient, wellness-centered approach to healthcare.

National Vaccine Information Center Questions Safety Of School-Based Swine Flu Vaccine Programs

The National Vaccine Information Center (NVIC) is calling on the Obama Administration and state Governors to provide evidence that it is necessary to give experimental swine flu vaccines to children in schools and that strong mechanisms for vaccine safety screening, recording, monitoring, reporting and vaccine injury compensation are in place. NVIC announced that parental concerns about vaccine safety and vaccine mandates will be addressed Oct. 2-4, 2009 in Washington, D.C. at the Fourth International Public Conference on Vaccination.

Wales Will Not Join National Pandemic Flu Service At This Stage

Health Minister Edwina Hart is reminding people that Wales will not be part of the National Pandemic Flu Service (NPHS) when it goes live in England.

Why Do People With Down Syndrome Have Less Cancer?

Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population. Since they have an extra copy of chromosome 21, it"s been proposed that people with Down syndrome may be getting an extra dose of one or more cancer-protective genes. The late cancer researcher Judah Folkman, MD, founder of the Vascular Biology Program at Children"s Hospital Boston, popularized the notion that they might be benefiting from a gene that blocks angiogenesis, the development of blood vessels essential for cancer"s growth, since their incidence of other angiogenesis-related diseases like macular degeneration is also lower. A study from Children"s confirms this idea in mice and human cells and identifies specific new therapeutic targets for treating cancer.

Survey Reveals Women Aren\'t Doing All They Can To Support Breast Health

A recent Yankelovich survey unveiled that although a large majority of women know there are simple steps they can take to support breast health, few women are taking the necessary actions. What"s more, 80 percent of the women surveyed have been personally affected by breast cancer or know someone who has been. To address this issue, One A Day Women"s Multivitamins is encouraging women to join a virtual march against breast cancer through the One A Day Women"s Take A Stand Campaign.

Sticky Protein Helps Reinforce Fragile Muscle Membranes

A new study by scientists at the University of Iowa shows why muscle membranes don"t rupture when healthy people exercise.

FDA Classifies Medtronic Voluntary February Recall For Intrepid™ Intervertebral Body Fusion Device As Class II

Medtronic, Inc. (NYSE: MDT) announced that the U.S. Food and Drug Administration (FDA) has classified its voluntary recall action of the Intrepid™ Intervertebral Body Fusion Device as a Class II recall. Medtronic initiated a voluntary recall of the product on February 6, 2009, and communicated the risk to physicians and hospitals. As of the date of this news release, all unused product has been retrieved and Medtronic has received confirmation of notification from all affected physicians and hospitals.

Typhoid Vaccine Effectively Prevents Disease In Children, Study Finds

"A typhoid vaccine proved effective in the slums of India, where it not only helped prevent infection in children who received it, but also those in close contact who were unvaccinated," according to a New England Journal of Medicine study published on Thursday, the AP/Washington Post reports (Chang, 7/22).

More Countries Move Ahead With H1N1 Vaccine Testing

The race to develop a H1N1 (swine flu) vaccine before the fall flu season ramped up Wednesday, after Australia launched the first human trials of the H1N1 vaccine and scientists from the U.S., China and Britain announced plans for human trials of an H1N1 vaccine in coming weeks, AFP/France24.com reports (7/23).

Shedding Light On \'Man-Eating\' Squid

News reports last week about scuba divers off San Diego being menaced by large numbers of Humboldt"s or jumbo squid have raised the ire of University of Rhode Island biologist Brad Seibel. As a leading expert on the species who has dived with them several times, he calls the reports "alarmist" and says the squid"s man-eating reputation is seriously overblown.

Identifying Pathways In The Brain To Understand The Underlying Molecular Mechanism Of Huntington\'s Disease

Florida Atlantic University researcher Dr. Jianning Wei, assistant professor of biomedical sciences in the Charles E. Schmidt College of Biomedical Science at FAU, has received a grant from the National Institutes of Health (NIH) to further her research into the molecular mechanisms of Huntington"s disease (HD). Named after American physician George Huntington, HD is a highly complex genetic, neurological disorder that causes certain nerve cells in the brain to waste away. The disease, characterized by a selective loss of neurons in the brain, affects the basal ganglia, which controls motor control, cognition, learning and emotions. It also affects the outer surface of the brain, or the cortex which controls thought, perception, and memory. Wei and her colleagues are working to identify the pathways in the brain that are altered in response to mutant proteins, as well as to understand the cellular processes impacted by the disease in order to facilitate the development of effective pharmacological interventions.

Synchronized Swimming Of Algae May Have Significant Implications For Human Health And Disease

Using high-speed cinematography, scientists at Cambridge University have discovered that individual algal cells can regulate the beating of their flagella in and out of synchrony in a manner that controls their swimming trajectories. Their research was published on the 24th July in the journal Science.

In Human-Dog Communication, Breed Is As Important As Species

Dog breeds selected to work in visual contact with humans, such as sheep dogs and gun dogs, are better able to comprehend a pointing gesture than those breeds that usually work without direct supervision. A series of tests, described in BioMed Central"s open access journal Behavioral and Brain Functions, should caution researchers against making simple generalizations about the effects of domestication and on dog-wolf differences in the utilization of human visual signals.

Disease Markers That Will Aid Arthritis Research

A combination of biochemical and MRI markers will allow improved measurement of osteoarthritis (OA) progression. The biomarkers, described in BioMed Central"s open access journal Arthritis Research and Therapy, will be useful for the design and interpretation of trials of new disease modifying drugs.

Revealing Leukemia-Initiating Cells

Two new studies reveal a way to increase the body"s appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. The key is targeting a protein on the surface of those cells that sends a "don"t eat me" signal to the macrophage immune cells that serve as a first line of defense, according to the reports in the July 24th issue of the journal Cell, a Cell Press publication.

Diabetes Educators Get First Taste Of Nevella(R) With Probiotics, The Only Sweetener Designed To Boost The Immune System

Designed to boost the immune system and promote health, probiotics are gaining popularity at the grocery, and Nevella® with Probiotics, made by Heartland Sweeteners, is the first and only such sweetener currently on the market. Diabetes educators will get an early preview of Nevella® with Probiotics at their annual conference in Atlanta in early August, immediately prior to widespread availability across the country.

Key Event In Prostate Cancer Progression Discovered By Scientists

A study led by researchers at the Ohio State University Comprehensive Cancer Center and Dana-Farber Cancer Institute reveals how late-stage, hormone-independent prostate tumors gain the ability to grow without need of hormones.

Stem Cells Not The Only Way To Fix A Broken Heart

Researchers appear to have a new way to fix a broken heart. They have devised a method to coax heart muscle cells into reentering the cell cycle, allowing the differentiated adult cells to divide and regenerate healthy heart tissue after a heart attack, according to studies in mice and rats reported in the July 24th issue of the journal Cell, a Cell Press publication. The key ingredient is a growth factor known as neuregulin1 (NRG1 for short), and the researchers suggest that the factor might one day be used to treat failing human hearts.

Do Chicago\'s Suburbs Hold The Key To Understanding West Nile Virus?

When Tony Goldberg is not whacking through the brush of central

Doctor Knows Best - Royal College Of Obstetricians And Gynaecologists

In a commentary published in BJOG: An International Journal of Obstetrics and Gynaecology, doctors discuss the types of information pregnant women would welcome and why the advice provided to women by doctors is considered trustworthy.

The National Committee To Preserve Social Security And Medicare - Protecting The Health And Economic Future Of Older Americans

"As the President himself has said, America does not face an entitlement

Sessions Announced For AHIP\'s Medicare & Medicaid Conferences Early And Team Registrations Available

Join America"s Health Insurance Plans (AHIP) September 13 - 17, 2009, along with senior health insurance plan executives, policymakers, and federal and state representatives for updates, analyses, and discussion on the leading issues for health insurance plans participating in Medicare and Medicaid. Whatever is of special interest to you, AHIP"s Medicare & Medicaid Conferences offer sound public policy analyses and access to best practices and insights to help you strengthen your work serving Medicare and Medicaid beneficiaries.

Most, But Not All, Canadians With Chronic Conditions Get Clinically Recommended Tests

Most Canadians with chronic conditions have a regular place of care, but there are some reported gaps in the management of their conditions according to a new study released today by the Canadian Institute for Health Information (CIHI). The study, Experiences With Primary Health Care in Canada, measures access to and quality of care from a patient perspective across Canada"s 10 provinces. The study is based on the responses of more than 11,000 people age 18 and older to Statistics Canada"s 2008 Canadian Survey of Experiences With Primary Health Care, which was jointly funded by CIHI and the Health Council of Canada.

Recession Stressful For Many Kids, Toughest On Poor And Uninsured

As the economy continues to falter, a poll released today shows that parents must make harder choices about how to spend what money they have, and children -- especially those who are uninsured or who are among the lowest income bracket -- are more at risk because of it.

96-Week MERIT ES Analysis Shows Efficacy Of Pfizer\'s HIV/AIDS Treatment Celsentri/Selzentry (Maraviroc) In Treatment-Naç¯ve HIV Patients

At 96-week follow up, data from the MERIT ES analysis show that treatment-naç¯ve HIV patients taking Celsentri/Selzentry (maraviroc), in combination with Combivir® (zidovudine/lamivudine) experienced comparable virologic suppression to undetectable levels and significantly greater increases in CD4 T-cell count through 96-weeks, compared to patients taking efavirenz in combination with zidovudine/ lamivudine. The data also show the favorable tolerability of Celsentri/Selzentry, which was associated with fewer discontinuations due to adverse events.1

Swine Flu Might Infect 40% Of The US Population In The Next 24 Months

Health authorities in the United States have voiced concern that 40% of the country"s whole population could be infected with the swine flu (H1N1) virus over the next 24 months. The estimates are based on data gleaned from the 1957 flu pandemic which killed nearly 70,000 people in the country. That pandemic was not as severe as the 1918-1919 Spanish flu one. If one hundred and twenty million people caught swine flu this time round, and vaccine campaigns were not successful, the eventual death toll could be in the hundreds of thousands.

What Is Pleurisy? What Causes Pleurisy?

Pleurisy, also known as pleuritis, is a condition that results from the swelling of the linings of the lungs and chest. The pleural cavity (area between lungs and inner chest wall) is created by two lubricated surfaces called pleura, the inner pleura lining the lungs and the outer lining the chest wall.

National Health Service Leaflets On Sex Among Teenagers, Elderly Spark Controversy In U.K.

Two leaflets from Britain"s National Health Service have provoked controversy over government messages on sexuality among teenagers and the elderly, the Washington Post reports. According to the Post, the leaflet for teens, titled "Pleasure," says that daily sex "keeps the doctor away." It also states, "Health promotion experts advocate five portions of fruit and [vegetables] a day and 30 minutes physical activity three times a week." It suggests that some form of sexual activity "twice a week" could have health benefits as well. The leaflet was issued by NHS in Sheffield, England, and is available to parents, youth workers and teachers nationwide. The leaflet for the elderly says that it is "never too late to experiment" sexually and offers information on dating services and contraception. The leaflet is available online, and 2,000 copies have been distributed to doctors" offices, health centers and libraries.Britain has the highest teen pregnancy rate in Western Europe, and the government has prioritized prevention-related policy measures by spending millions of dollars on awareness and contraception campaigns, the Post reports. The country also plans to make sex education mandatory in all public schools starting in 2010.After the teen leaflet appeared, "dismayed parents lit up message boards," and some educators argued that it "encouraged promiscuity," the Post reports. However, others said the leaflets are a welcome departure from traditional forms of sex education that focus on biology and disease prevention, rather than personal relationships. Hilary Pannack, CEO of the teen pregnancy not-for-profit Straight Talking, said that talking with teens about sexual pleasure "should be done with extreme caution" but that, in general, the leaflet is a "big turnaround for Britain." She added, "British people are very, very embarrassed talking to kids about sex."Steve Slack, the director of NHS" Center for HIV and Sexual Health in Sheffield and a co-author of the leaflet, said one of the objectives was to encourage teens to delay intercourse until they are ready and feel that they will enjoy it. He added that some of the leaflet"s ideas were inspired by the Netherlands, a country that is frequently referenced in British sex education debates because of its liberal attitudes toward discussing sex and its low teen pregnancy rates (Adam, Washington Post, 7/23).

In Cleveland, Obama Visits \'Model\' Clinic

"President Barack Obama arrived at the Cleveland Clinic without fanfareò€¦ Thursday afternoon" to visit the medical center he"s called a model of low-cost, high-quality care, the Cleveland Plain Dealer reports. Obama said he wasn"t seeking an endorsement from the hospital, only information. "There has been a lot of discussion in Washington about the very different model that we and the Mayo [Clinic] have, and he wanted to understand it better," Clinic CEO Dr. Delos "Toby" Cosgrove said (Zeltner and Townsend, 7/24).

Orszag, Sebelius And Emanuel Take Lead Roles In Health Debate

Various news outlets examined the powerful roles members of the Obama administration are taking in the health care debate.

Obama\'s Health Reform Pitch Leaves Questions Unanswered For Many Viewers

The New York Times spoke to several families as they watched President Obama"s Wednesday night news conference. Thirty-six year old Craig Brown found that the event, meant to explain and gain support for health reform proposals, left him with many questions. He and his wife "remain frustrated by the lack of available detail about his plan"s contours and cost. They say they feel they are being asked to buy on spec from a government they do not trust. ... A similar unease was apparent in three other living rooms where families gathered to watch the news conference."

Race Plays Role In Diagnosis And Treatment

CNN reports that African Americans and whites are treated differently by doctors. "While it"s extremely difficult to tell in any given situation how much race -- consciously or unconsciously -- plays a role in a doctor"s decision making, multiple studies over several decades have found doctors make different decisions for black patients and white patients even when they have the same medical problems and the same insurance."

Caspase-8 Plays An Important Role In Proliferation And Invasion Of Cancer Cells

Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. The study was published recently in the journal Cancer Research.

FDA Authorizes Emergency Use Of Another Test For 2009 H1N1 Influenza Virus

The U.S. Food and Drug Administration announced it has issued an Emergency Use Authorization (EUA) for a another diagnostic test for the 2009 H1N1 influenza virus, whose spread has caused the virus to be characterized as a pandemic by the World Health Organization.

UK Young People Want Better Information On Sexual Health

83% of young people surveyed by UNICEF UK and Terence Higgins Trust say they need a sexual health information service similar to the Government"s "Talk to Frank" drugs service.

Evidence Linking Agent Orange, Parkinson\'s, Heart Disease "Limited Or Suggestive", Report

Writers of a new report found "limited or suggestive evidence" that exposure to Agent Orange and other chemicals used in the Vietnam War is

Teen Pregnancy May Be Symptom, Not Cause, Of Emotional Distress

It would make sense that teenage mothers have a lot of psychological stress in their lives, but a new study shows that the distress comes before the pregnancy, not because of it.

CHMP Recommends Expanded Use Of ISENTRESS(R) (raltegravir), From MSD, In Adult Patients With HIV-1 Infection

Merck, Sharp & Dohme (MSD) received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) recommending expanded marketing authorisation for ISENTRESS® (raltegravir) in combination with other antiretroviral (ARV) medicinal products for the treatment of HIV-1 infection in all appropriate adult patients, including patients starting HIV therapy for the first time (treatment-naç¯ve), as well as treatment-experienced patients. The positive opinion will be reviewed by the European Commission, which grants marketing authorisation to the 27 countries that are members of the European Union (EU), as well as Iceland and Norway.

Veterinary Practices In UK Need Good Access To Occupational Health

Staff working in UK veterinary practices lack access to good occupational health advice warns a new study published in the scientific journal, Occupational Medicine. The research, the first published benchmark of occupational health risk management by vet practices in the UK, showed that despite veterinary surgeons and nurses being exposed to many occupational hazards less than a third of practices had trained staff in health and safety and only 14% sought advice from occupational health professionals.

Obama Starts Interviewing Supreme Court Candidates

President Obama on Tuesday started interviewing potential Supreme Court nominees, the Wall Street Journal reports. Senior White House adviser David Axelrod on Tuesday said that the administration is looking for a candidate who will give the powerless and disenfranchised people "a fair shake." Conservatives have said that the nominee will inevitably be a "judicial activist" because Obama has said that he wants to nominate a candidate who can use past experience and empathy for the underrepresented populations to help guide court decisions.Obama has started calling Republican senators in an effort to prevent the "bruising battles" past Supreme Court nominations have encountered during the confirmation process, the Journal reports. Obama called Sen. John Cornyn (R-Texas) on Tuesday, which Cornyn said was a "nice gesture." Sen. Tom Coburn (R-Okla.) spoke to Obama last week. Coburn said, "I don"t know that it"s going to be contentious," adding, "A prudent man would say, "I"m going to have a couple of Supreme Court nominees. Maybe I want to defuse the thing, the first one, so I can do what I want to do (with) the second one."" Axelrod said that Obama has spoken to 15 senators from both parties (Weisman/Bendavid, Wall Street Journal, 5/20).

University Of Queensland\'s Physiotherapist Treats World Champion Cyclist, Australia

Using ultrasound imaging, UQ physiotherapist Dr Julie Hides is helping a world-champion cyclist ride her bike pain free.

Lords Science Committee To Publish Follow-Up Report On Flu, UK

The House of Lords Science and Technology Committee will next week publish a short report on UK preparedness and pandemic influenza.

Swine Influenza Daily Update: 23 July 2009, Wales

The NPHS influenza surveillance scheme, which records reports of diagnoses of flufrom more than 300 GP practices across Wales, shows increasing levels of influenza activity across Wales. Further detail can be found on the NPHS website: see here.

American Medical Student Association Rejects New Organization Dedicated To Limiting Conflict Of Interest Regulation

The American Medical Student Association (AMSA) rejects the objectives of the Association of Clinical Researchers and Educators (ACRE), a newly formed organization that seeks to limit conflict of interest regulations. AMSA, the nation"s oldest and largest, independent association for physicians-in-training, is calling on the medical profession to continue to reduce the influence of pharmaceutical and medical device industry promotional activities, which research has proven to negatively affect patient care.

British Veterinary AssociationGuide To Partnerships In Veterinary Practice, UK

Continuing efforts to help its members form lasting and profitable partnerships and pre-empt disputes in veterinary practice, the British Veterinary Association (BVA) has revised its "Guide to partnerships in veterinary practice". It will be of particular interest to vets buying into a partnership for the first time and will also be helpful to partners revising their existing agreement.

2008 Workforce Census Published - Royal Pharmaceutical Society Of Great Britain

The Royal Pharmaceutical Society of Great Britain has published its fourth Pharmacy

Independent Study Confirms Superior Properties Of ZPC(TM) Enhanced Calcium Composite Bone Grafts

A recent independent study has confirmed Fortoss Vital(R), developed by the Pioneering Orthobiologics Company, Biocomposites, as an effective bone replacement material demonstrating superior bone regenerative properties due to its unique negative zeta potential control (ZPC(TM)).

Lutonix, Inc. Announces First Patient Enrollments In Three Separate Clinical Trials

Lutonix, Inc., a privately held medical device start-up, announced that patient enrollment is underway for its three simultaneous first-in-human clinical trials. The three studies are designed to test whether the proprietary Lutonix Drug Coated Balloon (DCB) Catheter is safe and effective in the treatment of vascular narrowing.

Highmark Provides Pediatricians With Res To Combat Childhood Obesity

Childhood obesity causes lifelong illness, leads to serious health complications in young adults and can lead to premature death in adulthood due to medical conditions such as diabetes, heart disease and hypertension. In addition to its significant human toll, childhood obesity alone costs the nation"s health care system some $14 billion annually.

In The Modern Post-PSA Era, Prostate Cancer Surgery May Not Be Necessary For Some Patients

Investigators at Memorial Sloan-Kettering Cancer Center (MSKCC), along with collaborating teams at the Cleveland Clinic and the University of Michigan, have completed the first large- scale, multi-institutional study of prostate cancer death after standard treatment to remove the prostate since PSA screening has become widely used as a method to screen for the disease.

Gender Difference In Heart Failure

Striking differences in the risk factors for developing heart failure (HF) and patient prognosis exist between men and women. Men and women may also respond differently to treatment, raising concerns about whether current practices provide the best care and reinforcing the urgency for sex-specific clinical trials for HF, according to a review article published in the August 4, 2009, issue of the Journal of the American College of Cardiology.

House Rejects Amendment To HHS Bill To Limit Funding To Planned Parenthood Clinics

The House on Friday voted 264-153 to approve its fiscal year 2010 Labor-HHS-Education spending bill (HB 3293) after voting on five amendments addressing price and policy issues, CQ Today reports. The bill would appropriate $730.5 billion. The Senate Appropriations Committee is scheduled to begin markup of its version of the bill on July 28.The House voted 183-247 to reject an amendment offered by Rep. Mike Pence (R-Ind.) that would have prohibited family planning funding through the Title X program to Planned Parenthood clinics. The House also voted 211-218 to reject an amendment by Rep. Mark Souder (R-Ind.) that would have stripped language to lift the ban on federal funding for needle-exchange programs. Lawmakers did approve an amendment offered by Rep. Darrell Issa (R-Calif.) to strip $5 million in funding for three NIH grants to study the HIV/AIDS risks associated with alcohol and substance use among sex workers in Asia and alcoholics in Russia (Wolfe, CQ Today, 7/24).

As They Debate Health Overhaul, Politicians Keep Eye On 2010

"Fifteen months before the midterm congressional election, health care is appearing in candidate stump speeches and interviews - particularly by Republican challengersò€¦ running in districts recently claimed by Democrats," USA Today reports. "That dynamic helps explain why a $1 trillion-plus health care bill stalled last week in Congress. ò€¦ Obama has said he wants lawmakers to finish health care by the end of the year, in part because it could become mired in election-year politics. All 435 members of the House and 36 members of the Senate are up for election in 2010."

H1N1 Could Infect Up To 2B People Within Next Two Years, WHO Says

The WHO on Friday said the "H1N1 swine-flu virus could infect up to two billion people over the next two years - about one of every three people in the world," VOA News reports. According to the news service, "A separate WHO report Friday said the virus has spread to almost every country in the world, killing about 800 people since it emerged in April" (7/25).

Gates Foundation Donates Additional $80M To Indian HIV-Prevention Program, Receives Indira Gandhi Prize For Peace, Disarmament And Development

The Bill & Melinda Gates Foundation will give an additional $80 million to Avahan, a foundation initiative launched in 2003 for HIV prevention programs in India, Bill Gates said on Thursday, the Seattle Times blog, "Business of Giving" reports. Previous foundation commitments to the program, "which involves more than 100 non-profits in six Indian states," total $258 million, the blog writes (Heim, 7/23).

The Endocrine Society Receives Commendation From The ACCME For Excellent Continuing Medical Education Programming

The Endocrine Society received the highest level of accreditation, "Accreditation with Commendation," as a provider of continuing medical education (CME) for physicians. Awarded by the Accreditation Council for Continuing Medical Education (ACCME), the accreditation term will run through July 31, 2015.

Poor Health Habits Discovered In Most Older Long-Term Cancer Survivors

A new study finds that most older long-term cancer survivors who are interested in diet and exercise actually have poor health habits. The study also reveals that those survivors who do exercise and watch their diet have improved physical health and quality of life. Published in the September 1, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society, the research indicates that greater efforts are needed to encourage elderly cancer survivors to live healthier lives.

Funding Allocated For Hospice Care, Wales

Health Minister Edwina Hart announced the allocation of ÷£4million Assembly Government funding for hospices and palliative care services across Wales.

How The Carrot Approach Facilitates Learning

People who are rewarded for making correct decisions learn quickly. While

Faster, Cheaper Genome Sequencing Featured At The 15-Minute Genome 2009 Industrial Physics Forum

In the race for faster, cheaper ways to read human genomes, Pacific Biosciences is hoping to set a new benchmark with technology that watches DNA being copied in real time. The device is being developed to sequence DNA at speeds 20,000 times faster than second-generation sequencers currently on the market and will ultimately have a price tag of $100 per genome.

Need For Reform Is Urgent, Health Care Leaders Say

By a wide margin, health care leaders believe that individuals should have a choice of public and private health plans, and strongly support other central components of health reform such as innovative provider payment reform and a national insurance health exchange with strong standard-setting authority. In addition, two-thirds (68%) of opinion leaders feel it is urgent to enact comprehensive health care reform this year, according to the latest Commonwealth Fund/Modern Healthcare Health Care Opinion Leaders Survey.

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing An Anti-inflammatory Role In Recovery From Spinal Cord Injury In Mice

Although macrophages are known as essential players in wound healing,

Cigarette Packaging Still Misleading Consumers Over Health Hazards

New research suggests that current regulations have failed to remove misleading information from cigarette packaging, revealing that a substantial majority of consumers believe cigarettes are less hazardous when the packs display words such as "silver" or "smooth," lower numbers incorporated into the brand name, lighter colours or pictures of filters.

Possible Treatment For Spinal Muscular Atrophy

Spinal Muscular Atrophy is the second-leading cause of infant mortality in the world.

ARIAD Announces Preliminary Results From Ongoing Clinical Trial Of Its Investigational, Bcr-Abl Inhibitor In Drug-Resistant Chronic Myeloid Leukemia

ARIAD Pharmaceuticals, Inc. (Nasdaq: ARIA) announced preliminary clinical data from an ongoing Phase 1 clinical trial of its investigational, multi-targeted kinase inhibitor, AP24534, in patients with advanced hematological cancers. The study results provide initial clinical evidence of hematologic, cytogenetic and molecular anti-cancer activity of AP24534 in heavily pretreated patients with resistant and refractory chronic myeloid leukemia (CML), including those with the T315I mutant variant of the target protein, Bcr-Abl. An abstract describing these data is being submitted for presentation at a major hematology meeting to be held later this year.

Sunshine Heart Provides C-Pulse U.S. Clinical Update

Sunshine Heart (ASX: SHC), a global medical device company focused on innovative heart assist technologies, announced that the first two patients implanted with the C-Pulse device in April 2009 at The Ohio State University Medical Center in Columbus, Ohio have successfully completed their 3 month follow-up evaluation.