Medical Devices
Oculus Innovative Sciences, Inc. (NASDAQ:OCLS), a healthcare company that develops, manufactures and markets a family of products based upon the Microcyn® Technology platform, which includes new formulations intended to reduce the use of antibiotics by preventing or treating infections including those caused by bacteria and viruses, has confirmed the effectiveness of Microcyn® Technology at inactivating the H1NI Swine Influenza A. In a virucidal time-kill suspension test conducted by an independent laboratory, BioScience Laboratories, Inc., the specific Microcyn Technology formulation reduced infectivity of the swine flu virus by 4.00log10 (99.99%) reduction after just 30-seconds exposure. BioScience Laboratories, working in cooperation with the U.S. Department of Agriculture, received formal approval to acquire, house and evaluate the specific swine influenza virus in April 2009.
The American Society for Radiation Oncology (ASTRO) is now accepting applications for Survivor Circle grants from cancer support organizations in Illinois. ASTRO awards these grants to non-disease site specific cancer support groups located in the state where ASTRO holds its Annual Meeting. ASTRO"s Annual Meeting will be held November 1-5, 2009, at McCormick Place West in Chicago.
According to new research* carried out by Lloydspharmacy, the UK"s leading community pharmacy chain, around 2.1million British holidaymakers and travellers are ignoring the need to protect themselves against malaria.
Vision loss costs Canadian society a staggering $15.8 billlion per year - significantly higher than previously estimated, according to new research study released on June 23, 2009, by CNIB and the Canadian Ophthalmological Society (COS). The study"s proponents say these costs, which are expected to increase dramatically in the years ahead, underscore the urgent need for Canada to develop a comprehensive national vision health plan.
The Associated Press reports on the costs of disease prevention: "When it comes to health care spending, an ounce of prevention is seldom worth a pound of cure. ...The truth is, shockingly few prevention efforts actually save the health care system money overall, despite claims by the president and some in Congress."
The Senate Commerce Committee has found that a flawed payment database produced by a UnitedHealth subsidiary and distributed to other major insurance companies has led insurers to underpay millions of out-of-network claims, forcing patients to make up the difference of health care providers" fees, the Wall Street Journal reports. Aetna, Cigna, WellPoint, and other large insurers used the data to calculate their "reasonable and customary" charges. They also provided UnitedHealth"s subsidiary, Ingenix, with historic data about their payments, which became the foundation of ongoing versions of the flawed payment models.
Fifty-three people were indicted in a major Medicare fraud crackdown in Detroit yesterday, just one day after eight were charged in a similar case in Miami.
Staying ahead of the upcoming drive to sell electronic health records to hospitals and physicians may be difficult for smaller vendors, Pharmawire/Financial Times reports. General Electric announced a program last week to provide health care organizations with financing options to purchase health technology through its financial services arm even as it sells electronic records through its health care wing. Other large vendors like Cerner and McKesson will be able to keep up, but smaller producers will be left behind, industry experts said.
Chembio Diagnostic Systems, Inc. (a wholly-owned subsidiary of Chembio Diagnostics, Inc.) (OTCBB: CEMI) has been awarded a three-year $3 million Small Business Innovative Research (SBIR) Phase II grant from the United States National Institutes of Health (NIH) to fully develop, validate, and commercialize a rapid diagnostic test for leptospirosis for general use worldwide. The test will be developed utilizing Chembio"s patented Dual Path Platform (DPP®) technology together with proprietary reagents developed by Cornell University and the Oswaldo Cruz Foundation at the Brazilian Ministry of Health.
Several Democratic female senators on Wednesday took to the floor in a series of speeches praising Supreme Court nominee Sonia Sotomayor and highlighting her judicial qualifications, the Boston Globe"s "Political Intelligence" reports. Sen. Amy Klobuchar (Minn.) -- a member of the Senate Judiciary Committee -- was joined by Sens. Mary Landrieu (La.), Claire McCaskill (Mo.) and Jeanne Shaheen (N.H.).In her address, Klobuchar said that Sotomayor"s experience "particularly resonated with me," adding that Sotomayor "understands the law is not just some dusty book in your basement" and that its interpretation has consequences. McCaskill said that Sotomayor is a nominee with "integrity, grit, intellect and the ability to pass judgment in the most difficult intellectual challenges that face a Supreme Court justice."According to "Political Intelligence," the floor speeches came after Klobuchar and others praised Sotomayor"s nomination at Monday"s annual convention of the left-leaning legal organization the American Constitution Society. In her speech, Klobuchar defended Sotomayor against conservative critics who have questioned the nominee"s temperament, citing complaints that Sotomayor was impatient with unprepared lawyers. Klobuchar said that she is "hoping that we would get to a point in this country where we could be appointing and confirming as many as rough and to-the-point female judges as we have appointed male judges" ("Political Intelligence," Boston Globe, 6/24).
Ohio students who participate in the Cleveland Metropolitan School District"s comprehensive sex education program show more knowledge and better attitudes toward safer-sex practices than students who do not participate, according to a study released Tuesday by Philliber Research Associates, the AP/Dayton Daily News reports. The school district uses a graduated sex education program for students in kindergarten through 12th grade. The program begins with instruction about the human body and inappropriate touching and progresses to discussions about sexually transmitted infections and relationships. The study, which was funded by the AIDS Funding Collaborative in Cleveland, found that more than 75% of parents of children in kindergarten through sixth grade approved of the program.The Collaborative for Comprehensive School Age Health, a coalition of northeast Ohio organizations that opposes abstinence-only sex education, said that the report validates the effectiveness of the city"s program. The study"s release coincides with advocates" efforts against two other sex education-related measures under consideration in the state budget plan. According to the AP/Daily News, the Republican-controlled state Senate wants to require the state Department of Education to apply for federal abstinence-only education funding. The state Senate also wants Ohio to continue to require legislative approval before any changes can be made in health education, although Gov. Ted Strickland (D) and the Democrat-controlled House want to change these requirements, the AP/Daily News reports (AP/Dayton Daily News, 6/23).
Cirrhosis is a world wide, bad prognosis liver disease and characterized by excessive collagen deposition and liver function damage. In our previous work, p90RSK is observed significantly up-regulated in association with elevated collagen type I levels in rat liver fibrosis. But detail mechanism of this phenomenon is still unknown.
President Barack Obama"s signature on a bill this week to grant the Food and Drug Administration (FDA) regulatory authority over tobacco was historic, and represents a step in the march to eliminate tobacco use in this country by 2047, two national tobacco experts said recently (June 25).
Contrary to predictions, males of high genetic quality are not very successful when it comes to fertilizing eggs. A new study on seed beetles by Swedish and Danish scientists Goran Arnqvist and Trine Bilde shows that when a female mates with several males, the males of low genetic quality are the most successful in fertilizing eggs. The study is published in this week"s issue of Science.
A UK consumer watchdog that is campaiging for clearer food labelling analysed a selection of pre-packed salads from high street supermarkets
"The details of President Obama"s new global health initiative have left many concerned that the financing described does not reflect the commitment required to lead the United States" efforts in the global fight against HIV and AIDS," Jennifer Delaney, executive director of Global Action for Children, writes in a New York Times letter to the editor. She adds that the Obama administration "needs to recognize that we cannot afford to scrimp on global health -- the cost of failure is too high. Our inaction threatens to forsake the more than 15 million children orphaned by AIDS, future parents and leaders of our world."As Eric Goosby, the recently nominated Global AIDS Coordinator, "begins his work in Washington, he faces serious obstacles to securing the full financing Congress has authorized to combat HIV and AIDS -- the financing our moral obligations demand," Delaney writes. She concludes, "We expect Dr. Goosby to be a fierce advocate for lifesaving HIV/AIDS and children"s programs. He can expect our tireless support in return" (Delaney, New York Times, 5/17).
The Center for Stem Cell & Regenerative Medicine (CSCRM), comprised of Case Western Reserve University (CWRU), Cleveland Clinic (CC), University Hospitals (UH), and Athersys, Inc. has received 5 million dollars from Ohio"s Third Frontier Commission under the Research Commercialization Program. The funding will help support new and innovative stem cell technologies including two commercial, four emerging and three pilot projects. This funding will be matched by each of the projects to create a $10 million grant benefiting stem cell and regenerative medicine in Ohio.
Merck & Co., Inc. (Whitehouse Station, N.J., U.S.A.), which operates in many countries as Merck Sharp & Dohme (MSD), has received a positive opinion from the European Medicines Agency"s (EMEA) Committee for Medicinal Products for Human Use (CHMP) recommending restricted first line use of "Januvia" (sitagliptin) for the treatment of type 2 diabetes. With this positive opinion, the CHMP recommends that sitagliptin be indicated to improve glycaemic control when diet and exercise alone do not provide adequate glycaemic control and when metformin is inappropriate due to contraindications or intolerance. If this opinion is accepted by the European Commission, sitagliptin will be the only diabetes treatment in the DPP-4 inhibitor class to have a restricted first line indication.
Polio, or poliomyelitis, is a highly contagious viral infection that can lead to paralysis, breathing problems, or even death. The term poliomyelitis is from the Greek poliÃös meaning "grey", myelÃös referencing the spinal cord, and -itis meaning inflammation.
The San Diego Tribune on Monday profiled the La Mesa, Calif.-based private psychiatric hospital Alvarado Parkway Institute. Some advocates say that the hospital is in a network of private hospitals that U.S. Immigration and Customs Enforcement uses to hold "severely" mentally ill detainees nationwide, often "out of reach of lawyers and even their families," the Tribune reports. The number of immigration detainees has increased dramatically over recent years. According to the Tribune, about 35,000 people are being detained in a system of public or private jails and detention centers awaiting the outcomes of their immigration cases. It is unknown how many of the detainees are mentally ill and how many are held in private facilities.Some disability-rights lawyers and advocates for the mentally ill say that conditions at many of the private facilities, including API, violate state and federal laws governing treatment of mentally ill people. Ann Menasche, a lawyer with the legal advocacy group Disability Rights California, last month sent a letter to ICE claiming that after visiting API and interviewing detainees, she found that the conditions are "excessive, unjustifiable and punitive." Menasche said that immigration detainees could not socialize, exercise or participate in group therapy, and noted that they also were kept shackled to hospital beds. She said the patients also are being denied their rights to daily visitors, access to a telephone and other lawful permissions. She said other patients were not subjected to such conditions. Earlier this month, Menasche sent another letter to county officials requesting that they investigate the facility.Hospital CEO Patrick Ziemer said that the measures taken at the hospital are done for security reasons required by ICE. He added, "Patients can move about and walk around, a few steps from their bed." ICE officials declined to answer specific questions about the treatment of patients at API but said in a statement that the agency is reviewing "visitation and telephone access practices for immigration detainees being housed in private psychiatric facilities to ensure they have appropriate access to both." Department of Homeland Security Secretary Janet Napolitano also has ordered a broader review of all ICE detention conditions (Moran, San Diego Tribune, 5/18).
Combating high blood pressure is a global challenge. But while developed countries have enjoyed reductions in cardiovascular disease over recent decades, Latin America has been less fortunate. In fact new research published in the journal Therapeutic Advances in Cardiovascular Disease shows that high blood pressure is on the increase in many Latin American countries, a situation set to worsen unless immediate action is taken.
As of January 2010, the Bulletin de la Sociç©tç© de Pathologie Exotique will join Springer"s publishing program. Founded in 1908 by Nobel Laureate Louis-Alphonse Laveran, the society celebrated its centenary last year. It plays a major role in the promotion of health issues and information on tropical pathology.
HIV-positive patients who don"t seek medical attention until they have a serious AIDS-related condition can reduce their risk of death or other complications by half if they get antiretroviral treatment early on, according to a new multicenter trial led by researchers at the Stanford University School of Medicine.
Five years from now, Lab scientists will be able to better determine how, when and why plutonium moves in soil and groundwater.
Much is often said about the glaring statistics showing that some racial and ethnic minorities face greater risks than whites when it comes to health.
The efficacy of preimplantation genetic screening (PGS) has been one of the most hotly disputed subjects in assisted reproduction over the past few years. None of the trials carried out so far has shown conclusively whether it works or not. Now the European Society of Human Reproduction and Embryology (ESHRE) Task Force on PGS has decided to try to find out if a novel method of doing PGS using polar body biopsy and chromosome array analysis offers a possible solution.
Southampton"s teaching hospitals have been recognised by one of the UK"s top medical organisations for leading the way in use of antibiotics in the fight against infection. The British Medical Association, the professional body for doctors and medical students, praised Southampton University Hospitals NHS Trust"s development of clear and simple antimicrobial prescribing guidelines for staff.
Morbidly obese seniors, age 65 and over, who had laparoscopic gastric bypass surgery lost nearly 76 percent of their excess weight after two years and had low complication rates and short hospital stays comparable to younger surgical patients, according to a new study presented today at the 26th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS).
In one of the most field-intensive efforts to explore the connection between malaria and tropical deforestation, a team led by Jonathan Patz, a specialist in the link between environment and health at the Nelson Institute for Environmental Studies at the University of Wisconsin-Madison, has established a strong correlation between the extent of forest destruction and the incidence of the Amazon"s most dangerous malaria vector, the mosquito Anopheles darlingi.
A UK wide public opinion poll conducted by Hamilton Lock for the British Medical Association released yesterday has revealed how worried the public is about the future funding of the health service in light of the recession. The poll was published to launch the Annual Conference of the BMA in Liverpool this week (29 June to 2 July 2009).
The AMA has written to Federal MPs and Senators urging them to support a number of key policy measures to reduce preventable health problems linked to excessive alcohol use, obesity and smoking.
Radiant Research, Inc. announced that it is actively recruiting subjects and establishing operational plans for upcoming H1N1 vaccine trials. The World Health Organization declared the H1N1 influenza outbreak a pandemic, and the CDC has shipped virus samples to several manufacturers with the hope of having vaccine available to the general public by the fall. Manufacturers will need to complete clinical trials prior to release of vaccine to the public.
Doctors will have greater clarity around releasing a patient"s full medical notes to insurance companies after the Privacy Commissioner concluded that the law allows insurers to collect only the information that they need to make insurance decisions.
The American Pharmacists Association (APhA) will publish in mid-July the second edition of Pagliaros" Comprehensive Guide to Drugs and Substances of Abuse. Written by veteran authors Louis A. Pagliaro and Ann Marie Pagliaro, the reference includes more than 100 monographs-11 of them new-dealing with each of the major drugs and substances of abuse used in North America, from acetone to zopiclone.
The Government of Canada is moving forward with proposed regulations to prohibit the advertisement, sale and importation of polycarbonate plastic baby bottles that contain bisphenol A, otherwise known as BPA, to reduce newborn and infant exposure to this substance, announced the Honourable Leona Aglukkaq, Minister of Health.
New research shines a light on the phenomenon of "cyber bullying," suggesting that nearly 1 in 10 children are bullied through electronic means such as text messages, and girls are more likely to be victims than boys are.
Scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio have for the first time constructed a genetic map of the parasite that causes schistosomiasis, a chronic intestinal infection that can damage internal organs and, in children, impair growth and cognitive development. Schistosome parasites are flatworms that infect more than 200 million people a year worldwide. Infection results in an estimated 200,000 deaths annually in sub-Saharan Africa alone, while 20 million suffer severe disease, according to the World Health Organization.
UCB announced that Neupro(R) (rotigotine transdermal patch) can now be prescribed to all patients with idiopathic Parkinson"s disease in Europe and is newly available for the symptomatic treatment of moderate to severe idiopathic Restless Legs Syndrome (RLS) in adults. This follows the decision of the European Commission to lift treatment restrictions on Neupro® in line with the recommendation of the European Medicines Agency (EMEA), issued on 29 May 2009.
Dr Brian Patterson, Chairman of the BMA"s Northern Ireland Council today (Tuesday 30 June 2009) warned that the health service financial belt will have to be tightened even further. In his speech to the 500 delegates at the BMA"s annual conference in Liverpool, Dr Patterson began by outlining that the Review of Public Administration (RPA), of which the BMA was supportive, has been completed. Dr Patterson said,
Plainview Milk Products Cooperative, Plainview, Minn., is voluntarily recalling instant nonfat dried milk, whey protein, fruit stabilizers, and gums (thickening agents) that it has manufactured over the past two years, because they might be contaminated with Salmonella. The company sells these products to other industry customers, including distributors and manufacturers, who may have incorporated them into their own products. None of Plainview"s products were sold directly to the public.
The recently released results of two large randomized trials suggest there are no big benefits from prostate cancer screening, and if
The two leading bodies representing GPs in the UK have backed a call by the Wellcome Trust for clearer guidance for GPs to ensure medical records can be safely used in research.
A research article published in the World Journal of Gastroenterology refers. The research team lead by Dr. Gabriela Beatriz Acosta, observed that the activity of GS was increased in the hippocampus in PH rats. There was a significant decrease in glutamate uptake in both brain areas, which was more marked in the hippocampus. The decrease in glutamate uptake might be caused by deficient transport function and persistent glutamate activity, which is not metabolized. This leads to severe damage in the cells of the central nervous system (CNS), associated with the presence of moderate ammonia concentration in the blood, as observed in this model. These results demonstrated that partial stricture of the portal vein is able to modify normal function in important areas of the rat brain.
A research article published in the World Journal of Gastroenterology refers. The research team led by Professor Yan Li from Shengjing Hospital of China Medical University studied the growth inhibitory effects of Alisol B acetat and determined its mechanism of antitumor activity in human gastric cancer cell line SGC7901.
MedImmune continues to advance its commitment to pediatric research with today"s announcement of the first observational prospective study designed to assess the burden of respiratory syncytial virus (RSV) among preterm infants 32-to-35 weeks gestational age (GA) in outpatient settings during their first year of life.
AlphaRx Inc. (OTCBB: ALRX) and Gaia BioPharma Limited reported positive pre-clinical results on GAI-122 injectable nanoemulsion in multiple in vitro and in vivo studies of memory impairment after prolonged anesthesia.
The high-intensity training undertaken by triathletes has a significant impact on the quality of their sperm, the 25th annual conference of the European Society of Human Reproduction and Embryology heard 29 June. Professor Diana Vaamonde, from the University of Cordoba Medical School, Cordoba, Spain, said that the triathletes who did the most cycling training had the worst sperm morphology.
The White House remains open to taxing some health benefits to help pay for health care reform despite campaigning against the move last year, The Washington Post reports.
New data show that at 24 months, patients in the chronic phase of Philadelphia chromosome positive (Ph+) chronic myeloid leukaemia (CML) who are intolerant or resistant to current first-line therapy (Glivec) experienced a rapid response and significant reduction in leukaemia burden when treated with 400mg Tasigna twice-daily1. Furthermore, the research shows that the majority of patients in both the chronic and accelerated phases of the disease are still alive at 2 years when treated with Tasigna1,2.
Plexxikon Inc., announced that key data related to PLX4032 and its development, will be presented in three separate presentations at the American Society of Clinical Oncology (ASCO) 2009 Annual Meeting taking place May 29 through June 2, 2009 in Orlando, Florida.
President Obama on Saturday released a statement marking National HIV Testing Day that urged U.S. residents to get tested for HIV and work toward reducing the spread of the virus, Bloomberg/Arizona Daily Star reports (Bloomberg/Arizona Daily Star, 6/28). Obama said in the statement, "Each of us must take responsibility for reducing our risk of acquiring or transmitting HIV and for supporting affected individuals and communities. This means getting tested for HIV and working to end the stigma and discrimination people living with HIV face." The White House also released a video message with Obama"s statement (White House release, 6/27).
Registered nurses and hospital employees will hold a patient care vigil Tuesday night, at UC Irvine Medical Center (UCIMC), to protest the administration"s retaliatory actions against Ethel Mark, an RN who has worked in the hospital"s cardiac care unit for the last seven years as a model patient advocate. Ms. Mark was informed that she could expect to be terminated by the beginning of July.
"Although HIV/AIDS continues to pose a serious threat to the nation"s health, HIV testing is a powerful weapon against the disease," Kevin Fenton, director of CDC"s National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, writes in a CNN.com opinion piece. Fenton writes that every 9 1/2 minutes someone in the U.S. becomes infected with HIV. "That"s 56,000 people every year," Fenton writes, adding, "But there"s something we can all do to help protect ourselves and our partners from this disease - get tested for HIV." He continues, "By increasing the number of people who know their HIV status, we can decrease the number of new HIV infections, and help save thousands of lives" (Fenton, CNN.com, 6/26).
The latest news on procedures, drugs and equipment in the field of cardiology will be presented at the European Society of Cardiology congress which will take place in Barcelona, from 29 August to 2 September.
A powerful new research facility at the heart of King"s Health Partners Academic Health Sciences Centre has been launched by Professor Dame Sally C Davies, Director General of Research and Development and Chief Scientific Adviser, Department of Health. The Biomedical Research Centre (BRC) Nucleus is funded by a ÷£3M infrastructure grant from South London and Maudsley Charitable Funds (÷£1.8M) and Guy"s and St Thomas" Charity (÷£1.2M) to create a unique centre housing key translational initiatives to support the development of novel therapies and treatments for mental health and related disorders.
Health Minister Leona Aglukkaq updated Canadians on the H1NI flu virus response and reemphasized the Government of Canada"s ongoing collaboration with its national and international partners to manage the spread of this virus. The Minister and Canada"s Chief Public Health Officer, Dr. David Butler-Jones will be participating in an international meeting on the global response to H1N1 flu virus in Cancun, Mexico from July 1-3.
An article in Science magazine this month highlights several promising new CF therapies, including VX-770 and VX-809 developed by Vertex Pharmaceuticals, as part of a look back at key moments in CF research since the discovery of the CF gene 20 years ago.
Aside from the obvious and immediate health problems that patients undergoing mechanical ventilation face, those who recover often do so with profound loss of strength and mobility that can impair their daily functioning and even lead to increased risk of morbidity and mortality down the line. Now research shows that functional status may be restored earlier to ICU patients by performing daily interruptions in sedation paired with mobilization and exercise, as led by physical and occupational therapists.
The Australian Nursing Federation joined other unions in celebrating the end of WorkChoices.
Please help us protect people with neuromuscular diseases from the potentially harmful impact of the recently released House Tri-Committee healthcare reform proposal. The package eliminates the first month purchase option for all power wheelchairs.
Today the Lance Armstrong Foundation and the American Cancer Society announced they have formed a first-of-its-kind partnership to empower and support survivors all over the world and aggressively address the global cancer burden. As part of its ongoing global commitment to fight cancer, the Society has become an international collaborating partner for the LIVESTRONG® Global Cancer Summit in Dublin, Ireland in August. The Society will actively participate in LIVESTRONG Global Cancer Campaign events at both the Tour de France in July and the Summit, beginning Aug. 24 in Dublin. John R. Seffrin, Ph.D., chief executive officer, American Cancer Society, will join the U.S. delegation to the Summit and address the 250 advocates selected from all over the world for their commitments to cancer control.
Recommendations for how the HHS Office of the Secretary will spend $400 million in funds for patient-centered research, also known as comparative effectiveness research, were released by Federal Coordinating Council for Comparative Effectiveness Research (CER). The report, mandated by the American Recovery and Reinvestment Act, is designed to help the HHS Secretary and lawmakers improve the quality of care for patients, and provide patients and doctors the best information possible to make decisions about health care.
When it comes to characteristics associated with muscle dysmorphia, there is no difference between bodybuilders who use steroids and those who do not, a University of Arkansas researcher found.
Centocor Ortho Biotech Inc. announced today that a federal jury has returned a verdict of $1.67 billion against Abbott Laboratories in a patent infringement suit.
New data presented at the British Society for Allergy and Clinical Immunology (BSACI) annual meeting demonstrate that Grazax® is the first tablet treatment to provide sustained disease control in patients with grass pollen rhinoconjunctivitis (hay fever) after the treatment period ended. This is the first time disease modification by sublingual allergy immunotherapy tablets has been achieved; effectively re-setting the immune system to reduce future allergic reactions to grass pollen.
A Kansas State University researcher is studying the potential health benefits of a specially bred purple sweet potato because its dominant purple color results in an increased amount of anti-cancer components.
In a study with important consequences for studies on the effects of chemicals on steroid responses in humans, a team of French and American scientists, including Michael E. Baker, PhD, professor in UC San Diego"s Department of Medicine, Division of Nephrology-Hypertension, have found that - contrary to earlier assumptions - enzymes used for the synthesis of steroids in insects, snails, octopuses and corals are unrelated to those used in humans.
Exercise requires the integrated activity of every organ and tissue in the body, and understanding how these respond to the decreased oxygen levels present at moderate to high altitude is the focus of the current special issue of High Altitude Medicine & Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. The entire issue is available free online at http://www.liebertpub.com/ham Guest Editor Peter D. Wagner, MD, Distinguished Professor of Medicine & Bioengineering at the University of California, San Diego, presents six review articles written by expert researchers in the field of high altitude medicine that explore various aspects of exercise at altitude, including muscle and nerve function, metabolic responses, and changes that occur at the cellular level.
Prof. Prakit Vathesatogkit, Executive Secretary of Action on Smoking and Health Foundation welcome the government policy of increasing cigarette tax. He believes that the tax increase will greatly benefit smokers in Thailand. This is due to the fact that the higher cigarette price will result in people smoking less or quit completely, especially in the lower income group.
Doctors at the Cedars-Sinai Heart Institute announced today the completion of the first procedure in which a patient"s own heart tissue was used to grow specialized heart stem cells that were then injected back into the patient"s heart in an effort to repair and re-grow healthy muscle in a heart that had been injured by a heart attack. The minimally-invasive procedure was completed on the first patient on Friday, June 26.
The British Veterinary Association (BVA) has called on Defra to abandon its plans for a new animal health body that will give responsibility for animal health to an independent board and leave responsibility for animal welfare with ministers. The BVA has also expressed deep concerns over the confusion caused by the new structure that could lead to delays in dealing with outbreaks of disease across the UK.
In two recent COPD studies sponsored by DEY LP, PARI"s LC Plus nebulizer and PRONEB compressors (Ultra and Ultra II) were used to show that nebulized formoterol fumarate (Perforomist, DEY LP, Mylan Inc.) improves pulmonary function.
Immunology pioneer Professor Chris Goodnow from The Australian National University has been elected as a Fellow of the prestigious UK and Commonwealth academy of science, The Royal Society.
The General Optical Council (GOC) is today reminding all optical businesses, students and supervisors to ensure their current arrangements for professional supervision of students meet the requirements outlined by the GOC, and examination or assessment bodies. This follows the recent Fitness to Practise (FTP) hearing involving Boots Opticians Ltd (a GOC-registered business); Trevor Burgess, a registered student dispensing optician; and Richard Simmons, a registered dispensing optician.
Caring for an elderly family member can be stressful and can pose health threats to caregivers. Steven Zarit, professor and head, Department of Human Development and Family Studies, Penn State, received a $3 million grant from the National Institute on Aging to study the effects of caregiving on familial caregivers. He will look at people who care for family members with dementia and how adult day care impacts the stress levels of all individuals involved.
The Supreme Court"s 5-4 reversal of a decision endorsed by a three-judge appellate panel that included Supreme Court nominee Sonia Sotomayor is attracting criticism from the judge"s conservative opponents but is not expected to have a significant effect on delaying her confirmation, the Washington Post reports. The appellate panel in 2008 upheld New Haven, Conn."s decision to discard a promotion test for firefighters after no blacks and only two Hispanics qualified for advancement after taking the test (Markon/Kane, Washington Post, 6/30). The panel"s ruling affirmed a lower court"s decision that the city had a right to discard the test based on a segment of civil rights law involving actions that have a "disparate impact" on minorities. A group of white and Hispanic firefighters who would have received promotions under the test sued, alleging reverse discrimination. Democrats and legal analysts said that Sotomayor was following legal precedent in the 2008 ruling and that it was the Supreme Court, which has the ability to exercise more discretion, that chose to make law by reversing the decision (Friedman, CongressDaily, 6/29). The Supreme Court typically reverses about 75% of the cases it reviews, according to legal experts. The court previously has reversed four of Sotomayor"s rulings and upheld three of her decisions, the Post reports. Tom Goldstein, a lawyer and founder of the SCOTUSblog Web site, said, "I don"t think it will persuade anybody who is inclined one way or another to change their views about Sotomayor" (Washington Post, 6/30). Sen. Charles Schumer (D-N.Y.), a member of the Senate Judiciary Committee, said, "The main charge against Sotomayor is that she will be an activist judge, but this decision clearly shows that she won"t." He said that the results of the case "won"t change things a wit," adding that "in fact, it bolsters (the claim) that she is mainstream" (CongressDaily, 6/29). Sen. Jeff Sessions (R-Ala.), the ranking Republican on the Senate Judiciary Committee, said the New Haven case "sharpens our focus on [Sotomayor"s] troubling speeches and writings" that "indicate ... that personal experiences and political views should influence a judge"s decisions." He added that the issue "will clearly be the subject of questioning" at Sotomayor"s confirmation hearing, which is scheduled to begin on Monday (Phillips, "The Caucus," New York Times, 6/29).
"Lawmakers working to overhaul the U.S. health-care system face a pressure-filled July after leaving town this week without resolving the biggest questions dividing Democrats and Republicans," Bloomberg reports. Democrats on the Senate Finance Committee - which observers deem most likely to come up with a passable, bipartisan bill - have been working to reduce the cost of the overhaul to gain Republican support, but had not yet released a proposal. Bloomberg adds: "While the Congressional Budget Office said options under consideration by the committee can keep the cost within Baucus"s goal of $1 trillion over 10 years, how to pay for the plan remains unsettled. So is structuring some kind of government-run competition for insurers. ... "Nothing has been set," Montana Democrat [Max] Baucus told reporters in the Capitol on June 25. The recess offers a chance for "taking stock," he said" (Jensen and Livkin, 6/29).
A conservative group wants every lawmaker to pledge to read the entire bill for comprehensive health reform before voting.
The Grameen Foundation on Tuesday launched the first application of its Application Laboratory (AppLab) project, which aims to use "the proliferation of mobile phones in Africa as a way to get information and services to poor communities in Uganda without Internet access," the Seattle Times" blog, the "Business of Giving," reports (Heim, 6/29).
Katherine Camacho Carr, CNM, PhD, a certified nurse-midwife, professor and assistant dean of graduate studies at the Seattle University College of Nursing, is the recipient of the 2009 Hattie Hemschemeyer Award from the American College of Nurse-Midwives (ACNM.) The "Hattie" is ACNM"s most prestigious award and was presented to Carr at ACNM"s 54th Annual Meeting in Seattle. Carr has been a resident of the Seattle area for 32 years.
Neural stem cells represent the cellular backup of our brain. These cells are capable of self-renewal to form new stem cells or differentiate into neurons, astrocytes or oligodendrocytes. Astrocytes have supportive functions in the environment of neurons, while oligodendrocytes form the myelin layer around axons in order to accelerate neuronal signal transmission. But how does a neural stem cell "know" which way it is supposed to develop? On the molecular level receptors of the Notch family play a significant role in this process. So far, only stimulating extracellular ligands of Notch receptors had been described. Biochemists of Goethe University Medical School now describe a long time assumed but not yet identified soluble Notch inhibitor.
"Patients, policymakers, and practitioners all agree that reliable, accurate, and consistent quality measures are essential elements in improving health care services. This report is a clear indication that the efforts hospitals continue to make to prevent and control infections are having a positive impact on patient care. Hospitals are actively developing and sharing infection control techniques and best practices, and have engrained in their organizations a zero tolerance policy for preventable patient harm.
People with ankle injuries who do not respond successfully to initial treatment may have a second chance at recovery, thanks to two new procedures developed to restore the injured area, according to a study published in the July 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).
A new report issued by the International Osteoporosis Foundation (IOF) and published in the scientific journal Osteoporosis International1, shows that populations across the globe are suffering from the impact of low levels of vitamin D. The problem is widespread and on the increase, with potentially severe repercussions for overall health and fracture rates.
Though many consider teaching math to young children to be unnecessary or inappropriate at this stage in their educational development, research shows that as early as infancy, children start to think about the world in mathematical ways -- a capacity that currently goes largely untapped in the nation"s preschools. In addition, studies have linked early success in math to later success in both math and reading.
The Health and Safety Executive has warned of the danger of not maintaining plant equipment after the death of a telescopic forklift truck driver, who was crushed between the descending arm and side of his vehicle.
A 9,000-mile trek in 100 hundred days around the perimeter of United States to raise money to cure ovarian cancer begins today. The cyclist, Craig Broeder, Ph.D., is an exercise physiologist and Fellow of the American College of Sports Medicine (ACSM) who is dedicating his ride to help fund research and build awareness about ovarian cancer.
Tomorrow"s Council of Australian Governments (COAG) meeting is a crucial opportunity to focus on achieving concrete long-term health improvements for Indigenous people, the AMA said.
Commenting on the news announced today by ESHRE"s European IVF monitoring consortium on the improvements in the quality, safety and efficacy of ART, Clare Lewis-Jones MBE, Chief Executive of Infertility Network UK said "We are angry that although the UK pioneered infertility treatment, we are still among the lowest providers in Europe of NHS treatment, and these figures show that availability in the UK is less than one third of that in Denmark. Recent measures announced by the Government to encourage implementation of the NICE Guideline have led to an improvement in the provision in some areas but more needs to be done by Primary Care Trusts in England to ensure that patients have equal and timely access to the full range of treatment recommended by NICE, and to tackle the ongoing variations in provision that exist across the country.
In response to a report by the Public Health Commission which says health messages need greater clarity and consistency to help people make the right choices, Chris Sorek, Chief Executive of Drinkaware, says:
Schering-Plough Corp., (NYSE: SGP) announced results from the Phase III ENGAGE clinical trial demonstrating that a single injection of corifollitropin alfa, first in the class of sustained follicle stimulants, achieved similar efficacy to recombinant follicle stimulating hormone (rFSH) given once daily for seven days. The ENGAGE data was presented along with data from the Phase III ENSURE trial and the Phase II REALIZE trial at the 25th annual meeting of the European Society of Human Reproduction and Embryology (ESHRE) in Amsterdam, The Netherlands.
Researchers in Berlin, Germany have ameliorated inflammation of the brain in mice caused by immune cells.
A clinical trial is being launched in three African countries of a drug that could eliminate onchocerciasis, or river blindness, one of the leading infectious causes of blindness across Africa. The drug, moxidectin, is being investigated for its potential to kill or sterilize the adult worms of Onchocerca volvulus, which cause onchocerciasis.
Many low-income women are failing to take the hormonal therapy prescribed as part of their breast cancer treatment, possibly lowering their survival rates, according to a study led by a researcher in the Duke Comprehensive Cancer Center.
For the first time, scientists have shown that chromosomal abnormalities are present in more than 90% of IVF embryos, even those produced by young, fertile couples. Ms Evelyne Vanneste, a PhD student in the Centre for Human Genetics and the University Fertility Center, Leuven University, Belgium, told the 25th annual conference of the European Society of Human Reproduction and Embryology today (Wednesday July 1), that the surprising finding meant that current techniques used in preimplantation genetic screening (PGS), where embryos are screened genetically in order to select the best embryo for transfer, do nothing to improve pregnancy and live birth rates. Indeed, it can lead to potentially viable embryos being discarded, she said.
For the first time, researchers have been able to identify genetic predictors of the potential success or failure of IVF treatment in blood. Dr. Cathy Allen, from the Rotunda Hospital, Dublin, Ireland, told the 25th annual conference of the European Society of Human Reproduction and Embryology today (Wednesday 1 July) that her research would help understand why IVF works for some patients but not for others.
Saying that the savings from chronic disease prevention and treatment "can fill the funding gap for health care reform," the New Jersey Partnership to Fight Chronic Disease (PFCD) was joined by key state business leaders in urging federal lawmakers to "take the savings and run" with a health care reform bill that works for all Americans.
AstraZeneca announced that it has received a licence by the European Medicines Agency (EMEA) for its oral targeted anti-cancer drug, gefitinib, for EGFR (epidermal growth factor receptor-tyrosine kinase) activating mutation positive patients with Non Small Cell Lung Cancer (NSCLC). NSCLC is the most common type of lung cancer and accounts for 80% of all lung cancer cases. [1] The licence means that for the first time, thousands [2] of patients undergoing first line treatment of NSCLC in the UK may benefit from a more effective, [3] oral alternative to doublet chemotherapy (UK standard of care) without many of the side effects associated with chemotherapy. [3]
British scientists have found a significant link between later retirement age and later onset of dementia in men.
Novocaine? Not necessarily. The widespread belief that dentists rely on Novocaine to make those office visits almost painless needs some updating, according to an article scheduled for the June 29 issue of Chemical & Engineering News, ACS" weekly newsmagazine. In fact, patients are more likely to get any of several other anesthetics than the century-old standby Novocaine, which once reigned as the archetypal dental anesthetic.
The California Medical Association announced it is endorsing propositions 1A, 1B and 1C in the statewide special election on Tuesday.
The U.N."s World Food Programme (WFP) said Wednesday a "lack of international funding and new restrictions by North Korea on its staff and where it can operate has left it unable to reach millions of hungry women and children in the impoverished country," AP/Taiwan News reports. According to the WFP, it has received 15 percent of the $504 million it needs to feed 6.2 million North Koreans (Sanderson, 7/1). The agency has had to reduce its goal of reaching all 6.2 million, and is now targeting 2.27 million people, Torben Due, the WPF"s country representative in North Korea.
Three Republican senators took their case against Democrats" health reform to a Texas Medical Center gathering Tuesday, warning that a government insurance option is a "gateway to a single-payer system," The Houston Chronicle reports.
The White House sought the help of actor Ashton Kutcher to promote National HIV Testing Day on June 27, through his Twitter page, Politico reports. Kutcher has over 2.5 million followers on Twitter, where he recently posted a link to a White House blog post and video commemorating the day. Reid Cherlin, White House assistant press secretary, said, "As technology impacts how and where people are communicating online, we are constantly looking for new ways to engage with the public," adding, "Our efforts to promote National HIV Testing Day included participation from popular users of Twitter, as well as broad social media engagement by agencies across the government." The White House also used Twitter to help connect people to HIV testing sites (Gavin, 6/29).
Commenting on the new research on Alzheimer"s by the the Institute of Psychiatry at King"s College London, Michelle Mitchell, Charity Director for Age Concern and Help the Aged said:
Today, the Prime Minister, Gordon Brown, said he was determined to keep the issue of maternal mortality high on the agenda of the G8 summit in Italy next week.
Start, a lifestyle-changing fitness program at the UPMC Center for Sports Medicine, currently is enrolling adults over age 40 for its summer session. Beginning July 18, sports medicine professionals will guide participants through fitness and education sessions twice weekly for three months, preparing them to run or walk the 5K portion of the Richard S. Caliguiri City of Pittsburgh Great Race on Sept. 27.
MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) and the University of Melbourne announced today an agreement to cooperate on investigating new therapeutic applications for MorphoSys"s MOR103 program. MOR103, a HuCAL antibody against human GM-CSF (Granulocyte macrophage-colony stimulating factor), is currently in development for the treatment of rheumatoid arthritis (RA). The collaboration announced today will focus on new therapeutic areas in which GM-CSF has recently been implicated in as-yet unpublished work of researchers at the University of Melbourne. As part of the expanded relationship, new patent applications have been filed, which are intended to broaden the patent position of the anti-GM-CSF approach.
Sucampo Pharma Americas, Inc., a wholly owned subsidiary of Sucampo Pharmaceuticals, Inc. (NASDAQ:SCMP), today reported top-line results from its phase 2 clinical trial of orally administered cobiprostone for the prevention of gastric ulcers and other gastrointestinal injuries in patients treated with non-steroidal anti-inflammatory drugs (NSAIDs).
Occupational therapist, Ms Hannah McIlhinney has been suspended from the
For years, genes have been considered the one and only way biological traits could be passed down through generations of organisms.
The frontiers of cell transplantation for cardiac repair are discussed in the current issue of Cell Transplantation (Vol. 18 No.3), now available on-line without charge at http://www.ingentaconnect.com/content/cog/ct.
The American Dietetic Association has released an updated position paper on vegetarian diets that concludes such diets, if well-planned, are healthful and nutritious for adults, infants, children and adolescents and can help prevent and treat chronic diseases including heart disease, cancer, obesity and diabetes.
An otherwise effective treatment for cystic fibrosis places patients at a high risk of sensorineural hearing loss, according to new research published in the July edition of Otolaryngology-Head and Neck Surgery.
The July issue of Ophthalmology, the journal of the American Academy of Ophthalmology, includes two studies that may influence clinical treatment of serious eye conditions. One study reports on silent cerebral infarcts (SCI) incidence and visual field loss in patients with normal-tension glaucoma; the other correlates inflammation biomarkers with corneal transplant rejection in herpes simplex patients.
Celiac disease, an immune system reaction to gluten in the diet, is over four times more common today than it was 50 years ago, according to findings of a Mayo Clinic study published this month in the journal Gastroenterology.
GENE THERAPY: Defining immune pathways limiting gene therapy
A team of Penn State scientists has shed light on the processes that lead to certain human DNA mutations that are implicated in hundreds of inherited diseases such as tuberous sclerosis and neurofibromatosis type 1. The results one day could influence the way couples who seek to have children receive genetic counseling. The team, led by Kateryna Makova, an associate professor of biology, also includes Erika Kvikstad, a graduate student in the Department of Biology, and Francesca Chiaromonte, an associate professor of statistics. Their findings will be published in the July 2009 issue of the journal Genome Research.
A Decade-Long campaign by the British Psychological Society to have statutory regulation for practitioner psychologists comes to fruition.
Better treatments for acute renal failure may be possible by blocking the mitochondrial fragmentation that occurs when kidneys don"t get enough blood or are exposed to toxins, researchers at the Medical College of Georgia report in the may issue of The Journal of Clinical Investigation.
Mental stress causes carotid artery dilation and increases brain blood flow. A series of ultrasound experiments, described in BioMed Central"s open access journal Cardiovascular Ultrasound, also found that this dilatory reflex was absent in people with high blood pressure.
PTSD (Post-Traumatic Stress Disorder) is triggered by a traumatic event - it is a kind of anxiety. The sufferer of PTSD may have experienced or seen an event that caused extreme fear, shock and/or a feeling of helplessness. Most of us experience a brief period of difficulty adjusting and coping with traumatic events. However, we gradually get better with time and healthy coping methods. On the other hand, there are times when symptoms get worse and may last for several months, or years. This study explains how PTSD can surface two years after a traumatic event. Another study found that one in eight Lower Manhattan residents likely had PTSD two to three years after the 9/11 attacks.
Some Iowa groups are concerned that the state"s criminal HIV transmission law adds to the stigma associated with the virus and hampers testing efforts, and are urging lawmakers to revisit the law, the Iowa Independent reports. According to the Independent, criminal transmission of HIV is classified among the second-most serious felonies that can be committed in the state. Those that have been convicted under the law have been sentenced to a few months to several decades in prison. Former state Rep. Ed Fallon (D) who supported the 1998 law, said, "It seems to me that since it is now 11, almost 12, years later, it wouldn"t be [a] bad time to take a look at it again," adding that "surely [there] are some tweaks or changes that the legislature could consider relevant to this law, especially with all the new knowledge we have of the disease" (Waddington, 7/1).
The Wellcome Trust on Thursday pledged 30 million pounds or about $50 million to support health research at more than 50 African institutions, Nature reports (Nayar, 7/1).
The Wall Street Journal examines how some U.S.-based health care programs are improving their treatment capabilities by learning from strategies used in developing countries. "When doctors running the AIDS clinic at the University of Alabama at Birmingham wanted to increase the number of patients who showed up for treatment, they turned to an unusual place for help: southern Africa," Wall Street Journal writes. By using an AIDS clinic in Zambia as a model, the Alabama clinic was able to decrease its no-show rate "from 31% in 2007 to 18% through June 2009."
The percentage of Americans with private health insurance is at its lowest level in 50 years, the Centers for Disease Control and Prevention said Wednesday, according to The Associated Press.
"The Food and Drug Administration announced (Wednesday) that it is requiring the smoking-cessation drugs Chantix and Zyban to carry the strongest type of safety warning possible to alert patients that the medications can cause serious mental health problems, including depression and suicide," the Washington Post reports (Stein, 7/1).
Skin from a factory - this has long been the dream of pharmacologists, chemists and doctors. Research has an urgent need for large quantities of "skin models", which can be used to determine if products such as creams and soaps, cleaning agents, medicines and adhesive bandages are compatible with skin, or if they instead will lead to irritation or allergic reactions for the consumer. Such test results are seen as more meaningful than those from animal experiments, and can even make such experiments largely superfluous.