Mental Health
A radically different approach to choosing the best treatment options for early breast cancer has been proposed by an international panel of experts in a report from the 11th St Gallen conference.
New research from North Carolina State University and the National Institute of Environmental Health Sciences (NIEHS) shows significant reproductive health effects in rats that have been exposed to bisphenol-A (BPA) at levels equivalent to or below the dose that has been thought not to produce any adverse effects.
The U.S. Food and Drug Administration (FDA) has approved Ilaris(R) (canakinumab) for the treatment of children and adults with cryopyrin-associated periodic syndrome (CAPS), which includes a number of rare, but life-long, auto-inflammatory disorders with debilitating symptoms and limited treatment options. The FDA granted priority review to Ilaris based on its potential to meet an important clinical need for patients with CAPS.
According to a report issued, drug safety leaders in pharmaceutical and biotechnology companies recognise the need to increase res, either internally or through partnerships, to comply with the safety regulations recently issued by the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMEA). The report - Safety First: The Impact of New Regulations on Clinical Development - is based on a survey of 140 industry safety specialists, including heads of medical, drug safety, pharmacovigilance, and regulatory departments within large and mid-sized pharmaceutical companies and biotech firms. The survey found that more than three-quarters (77%) of respondents believe that new safety regulations have had a considerable impact on the industry as companies implement drug safety regulations throughout the clinical development process.
NEARLY two thirds of the British public are neglecting their eyesight, according to the results of a shock survey released today.
The American Cancer Society - the nation"s leading voluntary health organization and largest non-governmental funder of cancer research and discovery - will present its Corporate Impact Awards June 19 during the Society-hosted Corporate Impact Conference in Chicago. The awards will recognize companies" engagement in targeted efforts to significantly impact cancer"s effect on the workplace, where disease-related expenditures and lost productivity costs annually surpass $228 billion; in contributing funds to the American Cancer Society to fight the disease; and in addressing responsible community involvement.
In the face of growing numbers of uninsured and low-income patients due to the economy, some free clinics are having difficulty meeting the increased demand, the Cleveland Plain Dealer reports. Since March, the Parma Health Ministry, in Cleveland, "which has only two volunteer primary care physicians who see patients in the evenings, has had to turn people away." Nicole Lamoureux, executive director of the National Association of Free Clinics, said the number of people seeking care at free clinics had increased by 40 to 50 percent in recent months, and that many of the newcomers have recently lost insurance coverage.
The pharmaceutical company Tibotec said it will join with the non-profit Global Alliance for Tuberculosis Development (TB Alliance) to speed up the development of the experimental TB drug TMC207, Health-e/IOL reports (Thom, Health-e/IOL, 6/18). Tibotec, which is a subsidiary of Johnson & Johnson, announced the news on Wednesday at the Pacific Health Summit in Seattle (Doughton, Seattle Times, 6/18).
CNN examines the success of an HIV testing campaign in Swaziland that urges couples to get tested together. "The nationwide initiative - funded by the United States government and implemented by global charity "Population Services International" (PSI) - is aimed at couples because tests can be useless if partners are not aware of the others" HIV status," CNN writes.
Health Secretary Andy Burnham has congratulated NHS staff for their success in meeting the Government"s target to reduce Clostridium. difficile (C. difficile) infections by 30 per cent two years ahead of schedule.
The NHS is taking a step closer to ending regional variation in the provision of IVF to couples who are unable to conceive naturally, Public Health Minister Gillian Merron announced today.
The National Infertility Awareness Campaign (NIAC) welcomed the document "Standardising Access Criteria to NHS Fertility Treatment"1 produced by Infertility Network UK (I N UK) and funded by the Department of Health.
Title:
- 3 confirmed cases in Wales.
A new survey completed by the British Association of Aesthetic Plastic Surgery (BAAPS) suggests that patients may experience higher complication rates with permanent cosmetic fillers than with other types of cosmetic injections. The survey reveals 38.5% of surgeons saw 1-3 patients over the past year experiencing complications with permanent facial fillers, and 23% of surgeons saw 1-3 patients in the past year with complications so severe surgery was needed to treat those complications. "Permanent fillers present challenges, particularly for inexperienced injectors," says Coalition leader Julius Few, MD, a plastic surgeon practicing in Chicago, IL. "In addition to potential complications that may develop years after injection, the challenge of a permanent, synthetic filler is the anticipation of aging changes and the need for outcomes that will not look unnatural over time. To date, fat continues to be the option closest to a permanent filler with a proven safety record."
The U.S. healthcare system is in critical need of basic change to enable more equitable, effective, efficient care. Experts in various fields of medicine, public health, and industry propose that telemedicine, or information technology enhanced healthcare, must be a core component of a viable healthcare reform strategy, a view they forcefully present in a white paper published online ahead of print in Telemedicine and e-Health, a peer-reviewed journal published by Mary Ann Liebert, Inc., the official journal of the American Telemedicine Association. The white paper is available free online
Researchers at the Max Planck Institute for Chemical Ecology in Jena and their colleagues from the Czech Academy of Sciences in Prague have developed a new method to quickly and reliably detect metabolites, such as sugars, fatty acids, amino acids and other organic substances from plant or animal tissue samples. One drop of blood -- less than one micro liter -- is sufficient to identify certain blood related metabolites.
A study by Oregon State University researchers suggests that school-based prevention programs begun in elementary school can significantly reduce problem behaviors in students.
The Juvenile Diabetes Research Foundation said recently that for the fourth time in 18 months, one of its biotech partners has signed a collaboration agreement with a large pharmaceutical company to move research on type 1 diabetes into the final phases of trials.
Cephalon, Inc. (Nasdaq: CEPH) announced results from a pivotal clinical trial of lestaurtinib (CEP-701) in patients with relapsed acute myelogenous leukemia (AML) expressing FLT3 activating mutations. The study was designed to show the benefit of lestaurtinib in this patient population when given in sequence with standard induction chemotherapy compared to those treated with standard induction chemotherapy alone. An analysis of the study showed that patients who were treated with lestaurtinib showed similar rates of complete response but no increased benefit in overall survival, compared to those who received induction chemotherapy alone.
According to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research, men with prostate cancer who consumed the active compounds in green tea demonstrated a significant reduction in serum markers predictive of prostate cancer progression.
Researchers have identified a genetic glitch that could lead to development of neuroblastoma, a deadly form of cancer that typically strikes children under 2.
A blueprint for a much-needed new generation of tuberculosis (TB) treatment has been developed by a team of scientists led at the University of Strathclyde in Glasgow.
Using virtual reality simulators to train surgeons improves performance and reduces operating time, finds a study published on bmj.com today.
The Dairy Council said on Friday that regulators need to raise their game and take a "common sense" approach to health and nutrition messages to the public. The plea comes in a week that has seen the European Food Safety Authority promise greater clarity in its procedures for assessing the science used to evaluate health claims and for better communications with applicants.
Indiana University School of Medicine researchers have developed a new breast cancer diagnostic marker that could enable physicians to more easily determine which patients have a less aggressive form of the disease that may not require chemotherapy treatment.
WHAT
School Nutrition Association president Dr. Katie Wilson, SNS announced new data today on the widespread availability of vegetarian school lunch options. Almost two thirds of school nutrition programs now offer a vegetarian school lunch on a consistent basis, up from 22% in 2003, according to the Association"s soon to be released 2009 School Nutrition Operations Report. The availability of vegetarian school lunches in a majority of districts is consistent with the overall trend in the past five years towards more nutritious school lunches emphasizing whole grains, fruits and vegetables, and low-fat dairy. The vegetarian choices also come in spite of federal school lunch reimbursements that have not kept pace with increased food and labor costs. Dr. Wilson presented the research findings at the National Conference on Childhood Obesity in Washington, DC today.
"Don"t expect the private insurance industry to go away under any kind of health-care reform initiative. That"s because most key health-reform measures gaining momentum in Washington not only leave private health plans intact but also may give them a greater role," The Chicago Tribune reports. Insurers also "got to ride the coattails" of the America Medical Association"s support for the private insurance system as President Barack Obama "sought the physicians" support" of his public insurance option. Health plans were "happy that the AMA stripped the words "public option" from a resolution."
What
The winner of the Medical Journal of Australia"s Dr Ross Ingram Memorial Essay
Due to overriding concern for the health and safety of Jerry"s Kids, the Muscular Dystrophy Association (MDA) announced today that it is immediately canceling the remainder of its annual summer camp program because of the H1N1 virus.
Clinical Data, Inc. (NASDAQ: CLDA) announced today that the United States Adopted Name Council (USAN) has approved the generic name vilazodone hydrochloride. Vilazodone, if approved, would represent a first-in-class drug for the treatment of depression, due to its novel dual mechanism of action as both a potent and selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the 5-hydroxytryptamine 1a (5-HT1A) receptor. Thus, vilazodone combines first-line therapy for depression with 5-HT1A partial agonism, an accepted adjunctive treatment for depression and a first-line therapy for anxiety disorders. Clinical Data has recently completed the second of two positive Phase III registration studies. Results of these studies will form the basis of a new drug application (NDA) that the Company intends to submit with the U.S. Food and Drug Administration (FDA) by the end of 2009.
AIDS Community Services of Western New York (ACS), a Buffalo-based agency that provides medical treatment and social services for individuals and families affected by HIV/AIDS, has lost a $288,500 grant from the Junior League of Buffalo that was to be used to expand a primary care center, the Charlotte Business Journal reports. The Junior League of Buffalo cited a contract agreement that said construction was to be completed by Dec. 31, 2008 as the reason for the decision; construction has yet to begin. ACS President Ronald Silverio said the agency will move forward with its expansion plans, although they will be further delayed, and anticipates that they will receive other funding to replace the loss. Since the ACS began planning this project, they have also experienced cuts in state funding, according to the Journal (Drury, Charlotte Business Journal, 6/19).
More pre-cancerous polyps were found in colonoscopies performed with deep sedation primarily using Propofol than with milder sedation in which patients remained conscious, according to a recent study conducted by Katherine Hoda, M.D. of Oregon Health and Science University. This improvement in cancer detection will save lives and reduce the number of patients requiring surgery and chemotherapy.
"Global health funding boosted by private donors has quadrupled since 1990, but the extra money has not always gone to the right countries and diseases, according to a pair of studies released Friday," in the journal Lancet, AFP/Google.com reports (Hood, AFP/Google.com, 6/18).
The Economist examines schistosomiasis in China. The disease, which is also called snail-fever, is the "world"s second-most prevalent tropical disease after malaria, affecting 207 million people of whom 726,000 are Chinese, according to the most recent official figures, from 2004," the Economist reports.
After years of declining teenage pregnancy rates and improved teen contraception use during the 1990s and early 2000s, the trends appeared to have flattened or even reversed among some groups of teens in recent years, according to a study from Columbia University"s Mailman School of Public Health and the Guttmacher Institute, the Christian Science Monitor reports. Researchers found that from 2003 to 2007, teens" contraceptive use declined by 10%, while their level of sexual activity did not change. The decrease in contraceptive use was particularly prevalent among black teens. The figures take into account the rate of contraception use as well as the types of contraceptives used, as methods vary in effectiveness. Teen condom use leveled off and in some cases declined, according to the study. The study also reported that the teen birth rate increased by 5% from 2005 to 2007. According to the study"s authors, the findings suggest a link between declining teen contraception use and the rise in abstinence-only education during former President George W. Bush"s administration. President Obama"s fiscal year 2010 budget proposal calls for redirecting some abstinence-only funds toward increased comprehensive sex education, the Monitor reports. In addition to the effects of abstinence-only sex education, the decline in condom use also could be tied to lessening concern about sexually transmitted infections, including HIV/AIDS. A shift in the teen population to include a higher number of Hispanics -- who have the highest rates of teen pregnancy and birth -- also could contribute to the findings. Laura Lindberg, one of the study"s authors and a senior research associate at Guttmacher, said, "In the end, this story is really about the loss of momentum." She added that although the statistical changes are small, "they raise concern about what the next few years will bring in this country." Sarah Brown, director of the National Campaign To Prevent Teen and Unplanned Pregnancy, noted that the proportion of births to unmarried women, particularly among women ages 20 to 24, also is on the upswing (Feldmann, Christian Science Monitor, 6/18).
The following summarizes selected women"s health-related blog entries.~ "A Radical Notion: Women"s Health Care as Mainstream," Cecile Richards, Huffington Post blogs: "To hammer ... home" the message that "Planned Parenthood and other essential community providers are the affordable, local access to basic preventive care that saves lives," the Planned Parenthood Action Center has introduced advertisements "educating the policy folks involved in fixing our health care system" about "why women"s health care needs to be taken care of in this mega-reform effort," Richards writes. She writes, "From cancer screenings to contraception to immunizations, the majority of women who go to women"s health care centers consider them their primary health care provider," adding, "In fact, more than 90% of what Planned Parenthood health centers do is preventive and primary care." According to Richards, "Essential community providers, including those who provide women"s health care, need to be part of any newly established health care system." She adds that "the three million patients who came to Planned Parenthood health centers last year can testify to it." Richards writes that "[f]amily planning and reproductive health care are unfortunately still not fully part of mainstream health care, even though 98% of women use contraception at some point in their lives -- there"s nothing more universal!" The "fact that women reproduce and, therefore, have different types of health care needs makes some folks on Capitol Hill go pale and start to sweat," Richards writes. She concludes, "Maybe one day we won"t need a special campaign to support women"s health," but "until then, Planned Parenthood is here to make sure women aren"t worse off after health care reform than before" (Richards, Huffington Post blogs, 6/18).~ "The Role of Medical Education in Preserving Abortion Access," Our Bodies, Our Blog: In response to a recent Salon opinion piece that examined whether there will be a next generation of abortion providers, the blog post discusses a few organizations that are "working to increase access to (accurate) abortion-related training." The blog includes links to Medical Students for Choice -- a group that "does student organizing and advocacy to influence medical school curricula, workshops ... and lectures on abortion techniques" -- and The Ryan Program -- which offers "funding, technical expertise, curriculum, workshops and other res to support training opportunities in abortion and contraception for ob-gyn residents." The blog entry also highlights the work of Physicians for Reproductive Choice and Health, which partners with members of the American Medical Student Association "to provide "project in a box" materials for medical students wanting to access and influence their schools" curricula on sexual and reproductive health" (Our Bodies, Our Blog, 6/18). ~ "Regulating Abortion May Be OK But Not To Avoid Sex-Selection," Marianne Mollmann, Huffington Post blogs: "Sex-selective abortion raises a multitude of overlapping ethical concerns regarding eugenics, population control and provider privilege or knowledge," according to Mollmann, advocacy director for the Human Rights Watch"s Women"s Rights Division. Mollmann writes that recent media reports indicating that sex-selective abortion occurs among some ethnic communities in the U.S. "has generated new discussion about what to do -- indeed what to think -- about the practice here." She continues that the "effect of abortion regulations depends on the context and motivation," adding that "[f]rom a human rights perspective, the regulation of medical procedures and interventions is legitimate and indeed often necessary so long as they are based on full respect for the full range of human rights." It is "perhaps tempting to hope that banning sex-selective abortions would safeguard the gender balance of future generations," but the "criminalization of abortion for whatever reason has in the past led only to underground and unsafe prac
On the observation of President Obama"s first 150 days in office, AIDS Healthcare Foundation (AHF), the nation"s largest AIDS organization, is continuing its "Change AIDS Obama" campaign with the release of a new online advocacy video chastising the president for his ongoing-and baffling-silence on AIDS.
A new study shows that high levels of job strain during early pregnancy are associated with reduced birthweight and an increased risk of delivering a small-for-gestational-age (SGA) infant.
It is unethical to stop healthy people from taking methylphenidate (Ritalin) to enhance their mental performance, says John Harris, Professor of Bioethics at the University of Manchester, in an article published on bmj.com today. He adds that society "ought to want [enhancement]" and that "it is not rational to be against human enhancement."
One in five people fall below the official poverty line following the death of their partner. "Hence the recent fall in the value of annuities, savings and investments means an even wider group of older people could face financial difficulties when their partner dies, whether these difficulties are short-lived or longer lasting," says researcher Anne Corden of the Social Policy Research Unit, University of York
Merck & Co., Inc. said it supports a proposal to provide additional assistance to Medicare Part D beneficiaries who have reached the coverage gap (donut hole) in their prescription benefit.
The Centers for Medicare & Medicaid Services (CMS) issued new guidance for nursing home surveyors, further defining and clarifying several important dimensions of care to help improve nursing home residents" quality of life and environment.
Immobilized microbes can break down potentially harmful phthalates, according to researchers in China, writing in the International Journal of Environment and Pollution. The microbes might be used to treat industrial waste water and so prevent these materials from entering the environment.
Eliminating the potential for catastrophic medical, energy and transportation disasters due to software failure is the aim of a new $21-million global research centre to be located at McMaster University. It will be one of the first such centres in the world.
The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting exceptional early career researchers and innovative cancer research, named 17 new Damon Runyon Fellows at its May 2009 Fellowship Award Committee review. The recipients of this prestigious, three-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country. The Fellowship is specifically intended to encourage the nation"s most promising young scientists to pursue careers in cancer research by providing them with independent funding ($140,000 each) to work on innovative projects.
The rapid development of modern neuroimaging has made a decisive improvement in the diagnosis of neurological illnesses. As Professor Filippi notes: "Neuroimaging makes new diagnostic tools available with the potential to quantify the extent of CNS injury, to define the nature of the different pathological substrates of the various CNS affections and to assess the functional changes following tissue damage with the ability to limit the clinical consequences of injury."
Epeius Biotechnologies stuns the medical and scientific communities with a dramatic demonstration of single-agent efficacy with its lead product, Rexin-G, for metastatic cancer. The landmark article (accessible online as of June 16, 2009 in Molecular Therapy, the Official Journal of The American Society of Gene Therapy, documents the results of two related studies using Rexin-G, a tumor-targeted anti-cancer agent designed to seek-out and destroy metastatic cancers that have spread throughout the body, while sparing normal cells and healthy tissues and organs. Following the FDA"s designation of Rexin-G as an Orphan Drug for the treatment of soft tissue sarcoma and osteosarcoma in 2008, the results of these two independent studies represent a major step toward gaining Accelerated Approval of Rexin-G for osteosarcoma in the United States.
Researchers at Children"s Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment. Their findings were published in the online Early Edition of the Proceedings of the National Academy of Sciences during the week of June 22.
Novexel, a speciality pharmaceutical company focused on the discovery and development of novel antibiotics designed to overcome the significant global problem of microbial resistance, announces that its two most advanced pipeline products NXL104 and NXL103 are the subject of four posters at the 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). The ECCMID conference is taking place in Helsinki between 16th and 19th May 2009.
It is no coincidence that the stroke theme is being given wide exposure at the ENS Congress. Stroke has become a major challenge for health policy and for medicine in general. It is now the second most common cause of death globally and the major cause of adult disability in the industrialized countries.
An important problem of patients with PD is not related to dopamine deficit. "PD patients suffer not only of motor but also of such non-motor disturbances as sleep disturbances, depression, psychosis, hallucinations or dementia. These disturbances require a precise diagnostic work up and specific, usually non dopaminergic medications." A whole series of studies being presented at the ENS meeting are devoted to this problem area.
There is also increasing knowledge about higher frequency of compulsive behavior in patients with PD compared to the general population. "These impulse control disorders such as pathological gambling, hyper-sexuality, compulsive shopping, compulsive eating or compulsive overuse of dopaminergic drugs can lead to monetary losses or worsen social handicap of PD patients," Professor Bassetti explains.
Scrubbing In: Good Health Care Doesn"t Come Cheap The Philadelphia Inquirer
Australia"s leading nutrition organisation, the Dietitians Association of Australia (DAA), has
Chronic asthma sufferers may find new relief in a simple, minimally invasive outpatient procedure known as bronchial thermoplasty, which uses controlled radiofrequency-generated heat to treat the muscles of the airways, preventing them from constricting and narrowing. The study, which was approved by the Food and Drug Administration (FDA), marks the most recent phase of investigational trials of the Alair System, the device used in the bronchial thermoplasty procedure. If approved, it would become the first non-pharmaceutical therapy to effectively treat severe asthma.
The UK"s life sciences companies have just two days remaining to tell the Government what it can do to help them succeed, as medical and healthcare industry specialist MedilinkWM brings its Voices of Industry Campaign to fruition.
Why the immune system of a pregnant woman does not attack her developing fetus is one of most remarkable features of pregnancy, and several underlying mechanisms have been described. However, Adrian Erlebacher and colleagues, at the New York University School of Medicine, New York, have now identified a new mechanism to explain why the mouse maternal immune system does not attack the fetuses.
The largest analysis of its kind has found that Caucasians are much more likely than people in other racial/ethnic groups to develop a rare bone and soft tissue cancer called Ewing"s sarcoma. In addition, among Caucasians with this cancer, men are more likely to die than women. Published in the August 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that examining the gender and racial differences related to Ewing"s sarcoma could provide a better understanding of the disease and could lead to improved treatments for patients.
-- 5 confirmed cases in Wales including two new cases:
When a dad changes diapers and makes pediatrician"s appointments, he"s more likely to stay interested and involved when his child makes the transition to school, said a new University of Illinois study that explores the role of parent involvement on student achievement.
The Department of Health"s Specialist Advisor for Autism, Elaine Hill,
A new study shows that older people who are thinner or are losing weight quickly are at a higher risk of developing dementia, especially if they started out overweight or obese. The research is published in the May 19, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Ceragenix Pharmaceuticals, Inc.("Ceragenix") (OTCBB:CGXP), a medical device company focused on infectious disease and dermatology, announced that researchers at National Jewish Health, led by Dr. Donald Y. Leung and Dr. Michael Howell, in collaboration with Dr. Paul B. Savage of Brigham Young University, have demonstrated in a series of in vitro experiments and preclinical animal testing that an investigational drug compound known as CSA-13 shows promise as a potential therapy to treat viral infections from the vaccinia virus. The research appears ahead of print in an advanced online publication of the Journal of Investigate Dermatology, the official journal of the Society for Investigative Dermatology. This work was funded by the National Institute of Allergy and Infectious Diseases Atopic Dermatitis Vaccinia Network.
Implicit stereotypes - thoughts that people may be unwilling to express or may not even know that they have - may have a powerful effect on gender equity in science and mathematics engagement and performance, according to a new study published this week in the Proceedings of the National Academy of Sciences.
Physiological and biochemical changes that occur during fasting in Ramadan are not a risk factor for stroke and do not affect the short-term survival of patients. This is the result of a study by a team of researchers from the Isfahan University of Medical Sicences (Iran). The data are being presented at the annual meeting of the European Neurological Society in Milan (Italy).
Telecoms, healthcare and display technology will be the major beneficiaries of a new generation of semiconductor lasers developed in a massive European research effort. Better cancer treatment, wider bandwidth and smaller, better displays could be on their way.
New technology to hear vibrations through the skull bone has been developed at Chalmers University of Technology. Besides investigating the function of a new implantable bone conduction hearing aid, Sabine Reinfeldt has studied the sensitivity for bone conducted sound and also examined the possibilities for a two-way communication system that is utilizing bone conduction in noisy environments.
Judicial Watch, the public interest group that investigates and prosecutes government corruption, announced today that it has obtained records from the Food and Drug Administration (FDA) documenting 28 deaths in 2008 associated with Gardasil, the vaccination for human papillomavirus (HPV), up from the 19 deaths in 2007. The total number of Gardasil-related deaths is 47 since the vaccine was approved in 2006. Overall, the FDA documented 6,723 "adverse events" related to Gardasil in 2008, of which 1,061 were considered "serious," and 142 considered "life threatening."
Poorer countries in Africa, Asia and Latin America are far from ready to deal with an H1N1 pandemic, and will need help to develop stockpiles
What are the costs of caring? A new project in the School of Psychology explores nurses" experience of distress and aims to determine if empathy with patients is associated with traumatic experience in nurses.
Medical scientists at the University of Leicester are investigating how a species of fish from the Pacific Ocean could help provide answers to tackling chronic conditions such as hereditary high blood pressure and kidney disease.
In this trial, a sample of alcohol-dependent patients received naltrexone, acamprosate or placebo for 12 weeks. While there were no differences in outcomes between treatment groups, those who believed they had been taking active medication consumed fewer alcoholic drinks and reported less alcohol dependence and cravings. That is, irrespective of actual treatment, perceived medication allocation predicted health outcomes.
Pediatric researchers have identified hundreds of gene variations that occur more frequently in children with attention-deficit hyperactivity disorder (ADHD) than in children without ADHD. Many of those genes were already known to be important for learning, behavior, brain function and neurodevelopment, but had not been previously associated with ADHD.
HealthLeaders-InterStudy, a leading provider of managed care market intelligence, reports that while health systems and physician groups in the Phoenix market seem to be ahead of the curve in adopting electronic medical records (EMR), there is a high rate of "deinstallation" wherein physician groups cancel their EMR contracts as a result of training, functionality or affordability issues. According to the recent Phoenix Market Overview, this trend is especially prevalent among smaller physician groups and points to the need for a simplified, affordable solution.
Doctors leaders called for an end to the ridiculous pricing of alcohol for off sales in light of findings from the Scottish Schools Adolescent Lifestyle and Substance Use Survey (SALSUS).
New research from scientists in the US and Greece suggests that the health and longevity effects of the Mediterranean Diet are more strongly
Critics are saying that Sen. Chris Dodd, D-Conn., cannot handle his role in financial regulatory reform while he sits in for ailing Sen. Edward Kennedy on the House"s health committee, Politico reports.
Major population centers such as those in New York and California have the highest numbers of HIV cases, however, many of the areas that have the highest rates of people with HIV are in the South, according to data from an online mapping tool launched by the National Minority Quality Forum yesterday, the AP/Minneapolis Star Tribune reports. The map, which is the first tool of its kind to look at HIV and AIDS cases on a county level, is based on 2006 data collected from states and cross-checked with CDC data. According to the mapping tool, of the 48 counties with the highest HIV prevalence rates, 25 are in Georgia. In addition, Florida, Georgia, South Carolina and Virginia have the highest prevalence rates for HIV cases that have progressed to AIDS (Stobbe, AP/Minneapolis Star Tribune, 6/22). In Virginia, Richmond, Petersburg and Norfolk were among the nation"s urban areas hardest hit by HIV/AIDS (Smith, Richmond Times-Dispatch, 6/23). Three metro counties in Kansas City, Mo., have HIV and AIDS rates that are higher than about 80 percent of counties nationwide, according to the data, NBC Action News reports (Ptacek, NBC Action News, 6/22).
The Latino HIV Task Force in Houston will offer free HIV testing as part of National HIV Testing Day on June 27, the Houston Chronicle reports. According to the Houston Department of Health and Human Services (HDHHS), Hispanics comprise 21 percent of the more than 16,000 HIV cases reported to the agency over the last 10 years and 17 percent of the nearly 26,000 AIDS cases since 1981. Porfirio Villarreal, HDHHS"s public information officer and media chair for the Task Force, said that HIV prevention is challenging among Hispanic communities because of stigma and difficulties in talking openly about sex. He added, "People who are undocumented in this country do not go test because they fear they may be deported, which is wrong." The task force was established in 2002 and has brought together several local health agencies and community-based organizations that offer medical treatment or programs focused on HIV/AIDS, according to the Chronicle (Lamkahouan, Houston Chronicle, 6/22).
Supreme Court nominee Judge Sonia Sotomayor has not become the "political lightning rod" Republican senators hoped for, leaving doubt among some members of the GOP that the nomination process will be controversial enough to help them or hurt Democrats in the 2010 elections, Politico reports. Sen. John Thune (R-S.D.) said that "at least so far" Sotomayor "doesn"t have the punch put there in terms of fundraising and recruiting." Thune said that one reason the GOP response to Sotomayor has been relatively quiet is that she is nominated to replace retiring Justice David Souter, rather than a more conservative justice. "When one of the conservatives leaves the court, then I think you"ll have a huge fight, and I think that will be very galvanizing," Thune said. Similarly, Sen. John Cornyn (R-Texas), a member of the Senate Judiciary Committee and chair of the National Republican Senatorial Committee, said he does not foresee Sotomayor"s nomination becoming a major issue in the 2010 campaigns. Sen. Jeff Sessions (R-Ala.), the ranking Republican on the Judiciary Committee, said that the GOP would use witnesses at Sotomayor"s confirmation hearing to present some opposition arguments (Raju, Politico, 6/22). Sessions and other Senate Republicans are preparing a series of speeches to highlight their concerns about Sotomayor, the Wall Street Journal reports. According to a Senate Republican aide, the focus of Sessions" speech will be Sotomayor"s role in the group LatinoJustice PRLDEF, for which she served as a board member from 1980 to 1992. Unless new information surfaces, there are few doubts that Sotomayor will be confirmed, the Journal reports (Bravin, Wall Street Journal, 6/22).
RNs Protest Cuts to Public Health, Pediatrics, TB Clinic, and Other Outpatient Services at San Joaquin County
Researchers at the University of Texas Medical Branch at Galveston have discovered two biochemical pathways that the Ebola virus relies on to infect cells. Using substances that block the activation of those pathways, they"ve prevented Ebola infection in cell culture experiments - potentially providing a critical early step in developing the first successful therapy for the deadly virus.
While Ontario women live longer than men, a majority are more likely to suffer from disability and chronic conditions, according to a new women"s health study by St. Michael"s Hospital researcher Dr. Arlene Bierman. What"s more, low-income women have more chronic conditions, greater disability and a shorter life expectancy than women in high-income groups.
Two young people, former child soldiers, who have transformed their brutal life experiences toward helping the more than one billion children whose lives are currently touched by war today told the international community, including Franco Frattini, the Italian Minister of Foreign Affairs, and Giovanni Alemanno, Mayor of Rome, what must be done to ensure that children are fully protected even in the heat of war.
Middle-aged women who had migraine headaches with aura (sensory disturbances, such as with vision, balance or speech) had a higher prevalence of brain lesions when they were older, compared to individuals without similar types of headaches, according to a study in the June 24 issue of JAMA.
The National Institutes of Health (NIH) has awarded scientists at Washington University School of Medicine in St. Louis four grants totaling $19 million to explore the trillions of microbes that inhabit the human body and determine how they contribute to good health and disease.
Approximately 5 million adults age 19 to 23 in the United States had no health insurance in 2006 for the entire year and 30 percent of them said they didn"t think it was worth the cost, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.
Narcolepsy - from the French narcolepsie, which was derived from the Greek narke meaning numbness and lepsis meaning attack or seizure - is a chronic sleep disorder where the brain is unable to regulate the body"s sleep-wake cycles. People with narcolepsy may feel an overwhelming urge to sleep at various points in the day, and they will often fall asleep spontaneously for a few seconds to a few minutes. In extreme cases, narcoleptics (people with narcolepsy) will remain asleep for over an hour.
Spherix Incorporated (Nasdaq CM: SPEX), an innovator in biotechnology for diabetes therapy, and a provider of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, announced positive preliminary results from a Phase 2 clinical trial of its novel compound, Naturlose(R) (D-tagatose), in the treatment and management of Type 2 diabetes. The Phase 2 trial is expected to be completed in early 2010.
Living Cell Technologies Limited (ASX: LCT; OTCQX: LVCLY) announced that the New Zealand Minister of Health, the Honourable Tony Ryall, has authorized LCT"s New Zealand Phase I/IIa clinical trial of DIABECELL(R) for insulin dependent diabetes.
According to the American Diabetes Association, nearly 24 million people have diabetes. Of that number, unfortunately, 5.7 million people are unaware that they have the disease. Diabetes can affect multiple parts of the body, including the kidneys, nerves, heart and even the mouth.
In a study published on bmj.com, experts report that prescription of antibiotics for respiratory illnesses should be standardized across Europe in order to reduce unsuitable prescribing and resistance.
On the heels of a successful partnership between MDVIP and Project Access in Palm Beach County, Florida, MDVIP will now roll out their second initiative to support the uninsured community in Northern Virginia. In collaboration with The INOVA Health Systems and Project Access of Northern Virginia (PANV), four of the local MDVIP-affiliated physicians will participate in a pilot program to provide services to uninsured patients who have diabetes, cardiovascular disease or may be considered a high-risk patient for either chronic condition.
Compugen Ltd. (NASDAQ:CGEN) announced that CGEN-25007, a novel peptide antagonist of gp96 with potent anti-inflammatory activity, has shown positive therapeutic effects in an animal model of inflammatory bowel disease (IBD), a commonly used term covering ulcerative colitis and Crohn"s disease.
Seventy-six percent of U.S. residents believe that abortion should be legal, a finding in keeping with public opinion over the past three decades, according to a Gallup poll released on Saturday, the AP/Boston Globe reports (AP/Boston Globe, 5/16). However, 51% of respondents identified themselves as "pro-life," while 42% said they are "pro-choice" (Gallup poll, 5/16). The finding marks the first time since Gallup began asking about abortion rights in 1995 that a majority of respondents said they consider themselves "pro-life" (Nadeau, Boston Herald, 5/16). Last year"s poll showed that 50% of respondents consider themselves "pro-choice," compared with 44% who said they are "pro-life" (Abcarian, Los Angeles Times, 5/16).The new poll found that 53% of respondents believe abortion should be legal under some circumstances, 23% believe it should be legal under any circumstances and 22% believe it should be illegal under any circumstances (Boston Herald, 5/16). The percentage of respondents who oppose abortion rights in all cases rose slightly from last year, while those who support abortion rights in all cases decreased slightly. The Los Angeles Times reports that the percentage of respondents who oppose abortion rights in all circumstances and those who support abortion rights in all circumstances is "a virtual tie." The results have a margin of sampling error of plus or minus three percentage points.Respondents who labeled themselves as moderates and Republicans accounted for most of the change in views compared with past polls, as Democrats" views remained consistent with previous years, according to the Los Angeles Times. Gallup in its analysis wrote that it is "possible" that President Obama "has pushed the public"s understanding of what it means to be "pro-choice" slightly to the left, politically" (Los Angeles Times, 5/16). The survey was conducted between May 7 and May 10 (AP/Boston Globe, 5/16).Nancy Keenan, president of NARAL Pro-Choice America, said, "I am pretty confident that Americans really don"t want Roe v. Wade overturned." She added that the increase in respondents identifying as "pro-life" does not "square with what has happened in the last several elections," noting that voters have rejected several antiabortion-rights ballot measures in South Dakota, California, Oregon and Colorado since 2005. However, Charmaine Yoest, president of Americans United for Life, said, "It tracks pretty much with what we"ve always known: People generally are pro-life depending on how you ask the question" (Los Angeles Times, 5/16).
Shire plc has launched a new UK adherence programme, called "Be Active", to support patients who have been prescribed Calcichew D3 Forte (1250mg calcium carbonate and 400IU colecalciferol). Current guidance highlights the importance of calcium and vitamin D supplementation in the elderly at risk of falls and fractures.1 2, 3 However, adherence to calcium and vitamin D supplementation in the UK is low, with 30% of UK patients regularly reporting missing a dose of calcium/vitamin D supplementation.4 This may contribute to more falls and fractures among the elderly 5, 6 and increase the burden on the healthcare system. 7, 8, 9
House Democrats readying a health reform bill without a price tag or a budget analysis will hear from business interests today that their plan is irrevocably broken and that they need to start from scratch, CongressDaily reports.
The American Recovery and Reinvestment Act (a.k.a. The Stimulus) set aside billions of dollars for hospitals to acquire electronic medical record systems, but one requirement for hospitals hoping to receive the money will be to share patient records with other facilities, the Dallas Morning News reports. "North Texas hospitals have talked for years about ways to share these records but have been unable to agree. Some participants in the discussions have said that"s because of concerns they might lose patients to competing hospitals" (Landers, 6/24).
IRIN Examines Hardships Facing Parents, Guardians Of Children Living With HIV/AIDS
Although it is "important for other young people to hear" Bristol Palin"s message "about how hard it is to be a teenage mother," her "lesson falls short by suggesting that any teen can successfully avoid premarital sex," a Philadelphia Inquirer editorial says. Palin, who gave birth in December 2008 after an unintended pregnancy and is the daughter of Alaska Gov. Sarah Palin (R), has "changed her tune" since she said in a February interview that teen abstinence is ""not realistic at all,"" the editorial states. It adds that Bristol Palin -- now an "abstinence ambassador" for the Candie"s Foundation -- recently said that abstinence is "realistic" and that it is the "harder choice, but it"s the safer choice."The editorial continues that Palin is correct that "[a]bstinence is the only foolproof way to avoid pregnancy" and sexually transmitted infections. However, "any viable lesson about avoiding teen pregnancy should include methods besides avoiding sex, including the use of condoms," the editorial says. Recent studies have shown that abstinence-only sex education programs have had "no measurable impact on delaying teens from having sex for the first time," according to the editorial, which adds that teen pregnancy rates rose 5% between 2005 and 2007 after years of declines. Additionally, three out of 10 U.S. girls will get pregnant by age 20, a figure that increases to more than 50% for Hispanics and blacks. The editorial concludes that teens "need frank talk about premarital sex that includes all of the viable options to avoid pregnancy" (Philadelphia Inquirer, 5/15).
The National Association of Chain Drug Stores (NACDS) today announced that the 2009 NACDS Pharmacy & Technology Conference will provide a forum at which to provide further recognition to Leonard J. DeMino, RPh., a chain pharmacy icon whose resume already includes some of the industry"s highest honors and achievements. This news comes as DeMino announces his retirement as senior pharmacy consultant to NACDS, effective in June 2009.
In his weekly radio and Internet address, President Obama discussed efforts by congressional leaders and health care industry groups on health care reform legislation, The Hill reports. He said that "while there remains a great deal of difficult work ahead, I am heartened by what we have seen these past few days: a willingness of those with different points of view and disparate interests to come together around common goals -- to embrace a shared sense of responsibility and make historic progress" (Youngman, The Hill, 5/16). He said, "I have always believed that it is better to talk than not to talk, that it is far more productive to reach over a divide than to shake your fist across it," which has "been an alien notion in Washington for far too long, but we are seeing that the ways of Washington are beginning to change."In the Republican radio and Internet address. Rep. Charles Boustany (R-La.), a cardiovascular surgeon, said that a "government takeover of health care will put bureaucrats in charge of health care decisions that should be made by families and doctors." He added, "It will limit treatment options and lead to rationed care," and "to pay for government health care, your taxes will be raised." Boustany, a member of the House Republican Health Care Solutions Group, said, "That is something we cannot support, and frankly, it would clearly violate some of the principles the president himself has endorsed" (Superville, AP/Washington Post, 5/16). In related news, Office of Management and Budget Director Peter Orszag on Sunday said on CNN"s "State of the Union" that the administration might support taxing health care benefits to health pay for health care reform (Barr, Politico, 5/17). Timeline
The NPA has launched an exciting new service enabling members to offer seasonal flu vaccinations to customers under a private Patient Group Direction (PGD) that the NPA is facilitating for its members, in line with our objective to provide additional business opportunities. Currently regulators require registration with the Health Care Commission and the involvement of a medical agency before a private PGD service can be set up. Members can now set up new services under private PGD without having to undertake this bureaucratic burden themselves.
As many as 15,000 people over 75 could be dying prematurely from cancer each year in the UK, according to research presented today at the National Cancer Intelligience Network (NCIN) conference.
The six industry groups that pledged to reduce health care spending growth by $2 trillion over 10 years on Friday issued a statement reaffirming their commitment to work toward the goal, Roll Call reports (Murray, Roll Call, 5/15). The industry groups in a letter sent to President Obama on May 10 wrote, "We will do our part to achieve your administration"s goal of decreasing by 1.5 percentage points the annual health care spending growth rate. ... This represents more than a 20% reduction in the projected rate of growth." The letter -- which was signed by the American Medical Association, the American Hospital Association, Pharmaceutical Research and Manufacturers of America, the Advanced Medical Technology Association, America"s Health Insurance Plans and the Service Employees International Union -- did not elaborate on what specific measures the groups would take to achieve such reductions (Kaiser Daily Health Policy Report, 5/12). Obama in a May 11 public announcement of the groups" pledge said the coalition"s goal was to cut the growth rate by 1.5 percentage points "each year," which would total $2 trillion over 10 years (Norman, CQ HealthBeat, 5/15).However, industry leaders who attended the meeting with Obama said that they did not promise specific year-by-year savings, but instead agreed to a more incremental approach (Kaiser Daily Health Policy Report, 5/15). Richard Umbdenstock, president of AHA, said, "There"s been a lot of misunderstanding that has caused a lot of consternation among our members." AHA sent its members a bulletin stating that "the groups did not support reducing the rate of health spending by 1.5 percentage points annually," and that the pledge was to eventually reduce the growth rate by 1.5 percentage points (CQ HealthBeat, 5/15).In response to media reports that said they were backing away from their pledge, the groups on Friday in a joint statement reiterated their vow. They wrote, "Our organizations are currently engaged in an intensive process to develop proposals to reduce the rate of increase in future health care costs" (Young, The Hill, 5/15). The statement also said, "We are committed to working together to bend the health care cost curve" and "to doing our part to make reform sustainable and to make the system more affordable and effective for patients and purchasers" (Budoff Brown, Politico, 5/18). It continued that "to be successful, we must take action in public-private partnership. We look forward to offering cost-savings recommendations in the weeks ahead." The Obama administration has requested specifics on the coalition"s cost-cutting plans by June 1. White House Office of Management and Budget Director Peter Orszag on Friday in a blog post wrote that it is "understandable" that the groups need to "ramp up" to the 1.5 percentage point reduction in spending. According to Orszag, "The groups have committed to significant reductions in the growth rate, thereby recognizing that substantial efficiencies can be captured in the health system. Some ramp-up time also does not materially affect the long-term impact from reducing the growth rate, on either national health expenditures or the federal budget" (CQ HealthBeat, 5/15). Orszag"s blog posting is available online.
Tobacco acts as a precipitating factor for headaches, specifically migraines. This is indicated in a study which shows that smokers have more migraine attacks and that smoking more than five cigarettes a day triggers this headache. The work has appeared in the Journal of Headache and Pain.
Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular behavior.
Advances in weight-loss surgery have made it as safe as any routine surgical procedure, according to a Duke University Medical Center researcher who reviewed data from nearly 60,000 patients and found it resulted in low complication and mortality rates.
Dr. Arne Ostman and colleagues at the Karolinska Institutet in Stockholm have identified a stromal marker for breast cancer progression. They present these findings in the July 2009 issue of the American Journal of Pathology.
Kirsten de Beurs, an assistant geography professor in Virginia Tech"s College of Natural Res, has received a NASA grant to direct a large international land abandonment study in Russia with Grigory Ioffe of Radford University, Geoffrey Henebry of South Dakota State University, and in-country collaborator Tatyana Nefedova.
US and UK scientists are developing a test for prostate cancer that uses samples of prostate fluid taken through a needle inserted under local
Like many diseases, causes for age-related macular degeneration (AMD) can be categorized as either "nature" or "nurture". Researchers think these factors, when used in the proper model, can be strong predictors of the disease.
Higher selenium levels in the blood may worsen prostate cancer in some men who already have the disease, according to a study by researchers at Dana-Farber Cancer Institute and the University of California, San Francisco.
A new study by scientists in California concluded that exposure to local traffic-generated air pollution is linked to an increased